NSG 533 ADV PHARM: MODULE 1: GI:
CHP 17 EXAM WITH COMPLETE
QUESTIONS AND ANSWERS { GRADED
A+}
Which drug class is most effective in treating erosive lesions:? - ✔✔PPIs
Name 4 H2RAs: - ✔✔Cimetidine (Tagamet)
Famotidine (Pepcid)
Ranitidine (Zantac)
Nizatidine (Axid)
What is the action of H2RAs? - ✔✔Decrease acid secretion by blocking
histamine 2-receptors in gastric parietal cells
Name 4 benefits of H2RAs - ✔✔1. Relieve GERD symptoms
, 2. Can be administered prophylactically
3. More effective at controlling chronic GERD symptoms than ANTACIDS
4. Intermittent & routine dosing possible based on degree of symptom control
needed.
Name 2 drawbacks of H2RAs - ✔✔1. Less effective in controlling chronic GERD
symptoms than PPIs
2. Renal elimination may require dose adjustment in kidney dysfunction patients
What are the side effects associated with H2RAs? - ✔✔H/A, nausea (Cimetidine),
weak inhibitor, common drug interactions, gynecomastia, & Vit B-12 deficiency
which affects patients' tolerance
Name the benefits of Antacids - ✔✔1. Useful for intermittent treatment of GERD
symptoms
2. Immediate symptom relief
3. Usually well-tolerated
What are the drawbacks of Antacids? - ✔✔1. Requires frequent dosing
2. Aluminum or Magnesium containing antacids may result in electrolyte
imbalances esp. in pts. w/renal impairment
CHP 17 EXAM WITH COMPLETE
QUESTIONS AND ANSWERS { GRADED
A+}
Which drug class is most effective in treating erosive lesions:? - ✔✔PPIs
Name 4 H2RAs: - ✔✔Cimetidine (Tagamet)
Famotidine (Pepcid)
Ranitidine (Zantac)
Nizatidine (Axid)
What is the action of H2RAs? - ✔✔Decrease acid secretion by blocking
histamine 2-receptors in gastric parietal cells
Name 4 benefits of H2RAs - ✔✔1. Relieve GERD symptoms
, 2. Can be administered prophylactically
3. More effective at controlling chronic GERD symptoms than ANTACIDS
4. Intermittent & routine dosing possible based on degree of symptom control
needed.
Name 2 drawbacks of H2RAs - ✔✔1. Less effective in controlling chronic GERD
symptoms than PPIs
2. Renal elimination may require dose adjustment in kidney dysfunction patients
What are the side effects associated with H2RAs? - ✔✔H/A, nausea (Cimetidine),
weak inhibitor, common drug interactions, gynecomastia, & Vit B-12 deficiency
which affects patients' tolerance
Name the benefits of Antacids - ✔✔1. Useful for intermittent treatment of GERD
symptoms
2. Immediate symptom relief
3. Usually well-tolerated
What are the drawbacks of Antacids? - ✔✔1. Requires frequent dosing
2. Aluminum or Magnesium containing antacids may result in electrolyte
imbalances esp. in pts. w/renal impairment
