Pancreas
Difference between acute and chronic pancreatitis
Acute: limited damage to secretory function of gland
Causes of pancreatitis
GET SMASHED
- Gallstones (MC)
- EtOH (MC)
- Trauma
- Steroids
- Mumps
- Autoimmune
- Scorpion venom
- Hypercalcemia
- ERCP
- Drugs
Endocrine functions of pancreas
Endocrine: Secretes insulin and Glucagon
, Exocrine function of pancreas
produces digestive pancreatic enzymes
- Lipase
- Protease
- Amylase
Acute Pancreatitis Pathophysiology
premature intrapancreatic activation of enzymes -> autodigestion
Pancreatic inflammatory response leads to...
increased vascular permeability and fluid shifts
Acute Pancreatitis Presentation
Sudden onset severe epigastric pain
Radiates to back
N/V
RUQ Tenderness
Fever
Acute Pancreatitis PE
Epigastric tenderness
Cullen's sign
Difference between acute and chronic pancreatitis
Acute: limited damage to secretory function of gland
Causes of pancreatitis
GET SMASHED
- Gallstones (MC)
- EtOH (MC)
- Trauma
- Steroids
- Mumps
- Autoimmune
- Scorpion venom
- Hypercalcemia
- ERCP
- Drugs
Endocrine functions of pancreas
Endocrine: Secretes insulin and Glucagon
, Exocrine function of pancreas
produces digestive pancreatic enzymes
- Lipase
- Protease
- Amylase
Acute Pancreatitis Pathophysiology
premature intrapancreatic activation of enzymes -> autodigestion
Pancreatic inflammatory response leads to...
increased vascular permeability and fluid shifts
Acute Pancreatitis Presentation
Sudden onset severe epigastric pain
Radiates to back
N/V
RUQ Tenderness
Fever
Acute Pancreatitis PE
Epigastric tenderness
Cullen's sign