Neonatologist: FPT and Septicemia
(McKenzie)
What causes clinical signs of infection
Host inflammatory response to the presence of pathogenic organisms
Localized inflammation progresses to __ which __
Localized inflammation progresses to systemic inflammation which causes clinical
changes
Neonatal routes of infection
Prepartum (Transplacental)
Postpartum (via outside environment)
Transplacental routes of neonatal infection
Maternal systemic circulation
Placentitis
Most common way to Diagnose Septicemia
Clinical signs of systemic inflammation (shock, tachycardia, tachypnea, fever,
hypothermia)
Additional PE signs (petechiae, jaundice, joint swelling, respiratory distress, diarrhea,
etc)
How to definitively dx septicemia
Blood culture to identify infectious agents (strongly indicated in severely ill foals)
+/- clin path (serum IgG, CBC, serum chem, blood gas)
CBC signs of septicemia
Leukopenia
Neutropenia
L shift (immature/band neutrophils)
Monocytosis
Inc or dec fibrinogen
Chem signs of septicemia
(McKenzie)
What causes clinical signs of infection
Host inflammatory response to the presence of pathogenic organisms
Localized inflammation progresses to __ which __
Localized inflammation progresses to systemic inflammation which causes clinical
changes
Neonatal routes of infection
Prepartum (Transplacental)
Postpartum (via outside environment)
Transplacental routes of neonatal infection
Maternal systemic circulation
Placentitis
Most common way to Diagnose Septicemia
Clinical signs of systemic inflammation (shock, tachycardia, tachypnea, fever,
hypothermia)
Additional PE signs (petechiae, jaundice, joint swelling, respiratory distress, diarrhea,
etc)
How to definitively dx septicemia
Blood culture to identify infectious agents (strongly indicated in severely ill foals)
+/- clin path (serum IgG, CBC, serum chem, blood gas)
CBC signs of septicemia
Leukopenia
Neutropenia
L shift (immature/band neutrophils)
Monocytosis
Inc or dec fibrinogen
Chem signs of septicemia
