Blood Bank BOC Exam 1
If a mother is R1r and a father is R1R1, which of the following statements best
describes the most probable genotypes of their 4 children?
1.25% Ror, 25% R1r, 50% R1R1
2.50% R1r, 50% R1R1
✅✅
3.100% R1r
4.100% R1R1 - -B
OIn an emergency situation, Rh negative RBCs are transfused into an Rh positive
person of the genotype DCe/DCe. The first antibody most likely to develop is:
A.Anti-c
B.Anti-d
✅✅
C.Anti-e
D.Anti-E - -A
c is more immunogenic than E.
OA patient's RBCs give the following reactions:
+ = Anti D, Anti C, Anti E, Anti c, Anti e
0 = Anti - f
The MPG of this patient is:
A.R1R2
B.R2r"
✅✅
C.Rzr
D.RzRz - -A
Anti-D and Anti-C are identified in the serum of a pregnant woman, gravida 2, para
1*. Ten months previously, she received Rh IG at 28 weeks gestation. Child is D
negative but C positive, while Mom is c negaitve. The most likely explanation for the
presence of Anti-D is that this antibody is:
A.Actually Anti-Cw
B.From the RhIG dose
✅✅
C.Actually Anti-G
D.Naturally occurring - -C
The phenomenon of an Rh+ person whose serum contains Anti-D is best explained
by:
A.Gene deletion
B.Missing antigen epitopes
✅✅
C.Trans position effect
D.Gene inhibition - -B
The Rh negative phenotype results from the complete deletion of what gene(s)?
, A.RHD and RHce
B.RHCE
✅✅-C
C.RHD
D.RHD and RHCE -
A mother is Rh- and the father is Rh+. Their baby is Rh-. It may be concluded that:
A.The father is homozygous for D
B.The mother is heterozygous for D
✅✅
C.The father is heterozygous for D
D.At least one of the 3 typings must be incorrect - -C
Which of the following genes on Chromosome 1 encodes for the 4 common antigen
combinations ce, cE, Ce and CE?
A.RHD
B.RHCE
✅✅
C.RHD and RHCE
D.RHd and Rhce - -B
A group B Rh-negative patient has a positive DAT. Which of the following situations
would occur?
A.All major crossmatches would be incompatible
B.The Weak D test and control would be positive
✅✅
C.The antibody screening test would be positive
D.The forward and reverse ABO groupings would not agree - -B
Autoantibodies demonstrating blood group specificity in warm autoimmune hemolytic
anemia are associated more often with what blood group?
A.Rh
B.I
✅✅
C.P
D.Duffy - -A
In what patient population may the reverse type be very weak? - ✅✅-Very old or
very young, not fully developed ABO antibodies
A patient is a subgroup of A (Asub) Rh positive with Anti-A1 in their serum. How
many units would you have to screen to find one unit that is compatible with the
patient's Anti-A1?
A.5
B.10
✅✅
C.15
D.20 - -A
1/ 0.2 = 5
If a mother is R1r and a father is R1R1, which of the following statements best
describes the most probable genotypes of their 4 children?
1.25% Ror, 25% R1r, 50% R1R1
2.50% R1r, 50% R1R1
✅✅
3.100% R1r
4.100% R1R1 - -B
OIn an emergency situation, Rh negative RBCs are transfused into an Rh positive
person of the genotype DCe/DCe. The first antibody most likely to develop is:
A.Anti-c
B.Anti-d
✅✅
C.Anti-e
D.Anti-E - -A
c is more immunogenic than E.
OA patient's RBCs give the following reactions:
+ = Anti D, Anti C, Anti E, Anti c, Anti e
0 = Anti - f
The MPG of this patient is:
A.R1R2
B.R2r"
✅✅
C.Rzr
D.RzRz - -A
Anti-D and Anti-C are identified in the serum of a pregnant woman, gravida 2, para
1*. Ten months previously, she received Rh IG at 28 weeks gestation. Child is D
negative but C positive, while Mom is c negaitve. The most likely explanation for the
presence of Anti-D is that this antibody is:
A.Actually Anti-Cw
B.From the RhIG dose
✅✅
C.Actually Anti-G
D.Naturally occurring - -C
The phenomenon of an Rh+ person whose serum contains Anti-D is best explained
by:
A.Gene deletion
B.Missing antigen epitopes
✅✅
C.Trans position effect
D.Gene inhibition - -B
The Rh negative phenotype results from the complete deletion of what gene(s)?
, A.RHD and RHce
B.RHCE
✅✅-C
C.RHD
D.RHD and RHCE -
A mother is Rh- and the father is Rh+. Their baby is Rh-. It may be concluded that:
A.The father is homozygous for D
B.The mother is heterozygous for D
✅✅
C.The father is heterozygous for D
D.At least one of the 3 typings must be incorrect - -C
Which of the following genes on Chromosome 1 encodes for the 4 common antigen
combinations ce, cE, Ce and CE?
A.RHD
B.RHCE
✅✅
C.RHD and RHCE
D.RHd and Rhce - -B
A group B Rh-negative patient has a positive DAT. Which of the following situations
would occur?
A.All major crossmatches would be incompatible
B.The Weak D test and control would be positive
✅✅
C.The antibody screening test would be positive
D.The forward and reverse ABO groupings would not agree - -B
Autoantibodies demonstrating blood group specificity in warm autoimmune hemolytic
anemia are associated more often with what blood group?
A.Rh
B.I
✅✅
C.P
D.Duffy - -A
In what patient population may the reverse type be very weak? - ✅✅-Very old or
very young, not fully developed ABO antibodies
A patient is a subgroup of A (Asub) Rh positive with Anti-A1 in their serum. How
many units would you have to screen to find one unit that is compatible with the
patient's Anti-A1?
A.5
B.10
✅✅
C.15
D.20 - -A
1/ 0.2 = 5
