BICH 411 Final Exam
Which of the following statements about eukaryotes is not true - ANS-They are also
called archaea
The bulk of aerobic metabolism in eukaryotic cells takes place in - ANS-the
mitochondrai
Whic of the following atoms commonly found in biological molecules are often
hydrogen-bond acceptors - ANS-oxygen and nitrogen
What functional groups are present on this molecule - ANS-hydroxyl and aldehyde
Which of the following statements regarding ATP is true - ANS-both b and c are correct
The pH of a solution of 0.1 M NaOH is - ANS-13
The Henderson-Hasselbalch equation - ANS-relates the pH of a solution to the pKa and
the concentrations of acid and conjugate base
The conversion of glucose-6-phosphate to glucose-1-phosphate has a deltaGnot of 8.4
kJ/mol. What can be said about the value of Keq - ANS-Keq < 1
A reaction with a ____ deltaH and a ____ deltaS will never be spontaneous -
ANS-positive, negative
The delta G for the conversion of G6P to F6P is +1.7 kJ/mol. In a particular human cell
the concentration G6P is 8.0 microM and the concentrationF6P is 1.0 microM. Calculate
the deltaGprime of the reaction as it occurs in this cell at 37 degrees C - ANS--3.7
kJ/mol
For the reaction of ATP + H2O --> ADP + Pi + H+, the biochemical standard state
conditions would include all of the following EXCEPT - ANS-concentration of ATP would
be 5 mM
Entropy, S, is exactly zero at - ANS-0 K
Which of the choices correctly ranks the following compounds from lowest level of
oxidation to highest level of oxidation - ANS-2 < 1 < 3
, Consider the following metabolic reaction:
Succinyl CoA + Acetoacetate --> Acetoacetyl-CoA + Succinate deltaG0prime = -1.25
kJ/mol
What is the Keq for the reaction at 25 degrees C - ANS-1.66
Which of the numbered arrows in the figure points toward a high-energy
phosphoanhydride bond - ANS-5
Given that the standard reduction potential of oxaloacetate is -0.166 V and the standard
reduction potential of NAD+ is -0.315 V. What is the deltaE0' for the oxidation of malate
by NAD+ - ANS--0.147 V
Which of the following is one factor that contributes to the large negative standard free
energy change for the reaction shown below
ATP --> ADP + Pi - ANS-The decrease in nagative charge repulsion in the products
compared to reactants
In eukaryotes, glycolysis typically occurs in the - ANS-cytosol
Acetyl-CoA contains a ___ bond which often provides the energy required for
substrate-level phosphorylation - ANS-thioester
What are teh correct coenzyme forms that correspond to X and Y in the following
reaction as catalyzed by lactate dehydrogenase? Pyruvate + X -> Lactate + Y - ANS-X
= NADH, Y = NAD+
The pH of a sample of blood is 7.4, while gastric juice is pH 1.4. The blood sample has -
ANS-one million times lower [H+] than the gastric juice
Which of the following is the best explanation for the hydrophobic effect - ANS-It is an
entropic effect, caused by the desire of water molecules to increase thier entropy by
excluding hydrophobic groups, which they must otherwise surround with highly ordered
structures
Osmotic pressure is a function of - ANS-solute concentration
Which of the following statements about eukaryotes is not true - ANS-They are also
called archaea
The bulk of aerobic metabolism in eukaryotic cells takes place in - ANS-the
mitochondrai
Whic of the following atoms commonly found in biological molecules are often
hydrogen-bond acceptors - ANS-oxygen and nitrogen
What functional groups are present on this molecule - ANS-hydroxyl and aldehyde
Which of the following statements regarding ATP is true - ANS-both b and c are correct
The pH of a solution of 0.1 M NaOH is - ANS-13
The Henderson-Hasselbalch equation - ANS-relates the pH of a solution to the pKa and
the concentrations of acid and conjugate base
The conversion of glucose-6-phosphate to glucose-1-phosphate has a deltaGnot of 8.4
kJ/mol. What can be said about the value of Keq - ANS-Keq < 1
A reaction with a ____ deltaH and a ____ deltaS will never be spontaneous -
ANS-positive, negative
The delta G for the conversion of G6P to F6P is +1.7 kJ/mol. In a particular human cell
the concentration G6P is 8.0 microM and the concentrationF6P is 1.0 microM. Calculate
the deltaGprime of the reaction as it occurs in this cell at 37 degrees C - ANS--3.7
kJ/mol
For the reaction of ATP + H2O --> ADP + Pi + H+, the biochemical standard state
conditions would include all of the following EXCEPT - ANS-concentration of ATP would
be 5 mM
Entropy, S, is exactly zero at - ANS-0 K
Which of the choices correctly ranks the following compounds from lowest level of
oxidation to highest level of oxidation - ANS-2 < 1 < 3
, Consider the following metabolic reaction:
Succinyl CoA + Acetoacetate --> Acetoacetyl-CoA + Succinate deltaG0prime = -1.25
kJ/mol
What is the Keq for the reaction at 25 degrees C - ANS-1.66
Which of the numbered arrows in the figure points toward a high-energy
phosphoanhydride bond - ANS-5
Given that the standard reduction potential of oxaloacetate is -0.166 V and the standard
reduction potential of NAD+ is -0.315 V. What is the deltaE0' for the oxidation of malate
by NAD+ - ANS--0.147 V
Which of the following is one factor that contributes to the large negative standard free
energy change for the reaction shown below
ATP --> ADP + Pi - ANS-The decrease in nagative charge repulsion in the products
compared to reactants
In eukaryotes, glycolysis typically occurs in the - ANS-cytosol
Acetyl-CoA contains a ___ bond which often provides the energy required for
substrate-level phosphorylation - ANS-thioester
What are teh correct coenzyme forms that correspond to X and Y in the following
reaction as catalyzed by lactate dehydrogenase? Pyruvate + X -> Lactate + Y - ANS-X
= NADH, Y = NAD+
The pH of a sample of blood is 7.4, while gastric juice is pH 1.4. The blood sample has -
ANS-one million times lower [H+] than the gastric juice
Which of the following is the best explanation for the hydrophobic effect - ANS-It is an
entropic effect, caused by the desire of water molecules to increase thier entropy by
excluding hydrophobic groups, which they must otherwise surround with highly ordered
structures
Osmotic pressure is a function of - ANS-solute concentration
