Bio Core II Exam 1 | Actual Exam
Questions | 100% Correct Answers |
Verified 2024 Version
which of the following statements regarding a DNA double helix is always true? - ✔✔the amount of
adenine is equal to the amount of thymine, and the amount of guanine is equal to the amount of
cytosine
working in a coroner's office, you are investigating the mysterious death of a person found in the
wooded area in the spring of the year. during a cellular analysis of this body, you learn that the levels of
mRNA that can be obtained from critical tissues are very low, and you find mushrooms in the contents of
the stomach. after examination of the mushrooms, you learn that they are a species of Aminita, and a
search of the Internet reveals that a toxin in this fungus inhibits RNA polymerase. However this isn't very
specific information. to be more certain of the cause of death in this case, you would need to verify that
the alpha-aminitin inhibits which eukaryotic RNA polymerase? - ✔✔RNA polymerase II
a prokaryotic mRNA transcript is - ✔✔translated as it is being transcribed
in eukaryotes, transcription is initiated by the formation of a pre initiation complex of transcription
factors and RNA polymerase at the TATA box of the promoter. give the correct order of the steps below: -
✔✔A: the TFIID complex containing the TATA box binding proteins binds to the TATA box
B: TFIIA and TFIIB bind to the initiation complex
E: TFIIF binds to RNA polymerase and this complex adds to the complex assembling at the TATA box
D: TFIIE and TFIIH bind to the complex, and the helicase function of TRIIH produces a small bubble in the
double-stranded DNA
C: RNA polymerase begins transcribing the sense strand of the DNA producing a complementary RNA
which form of DNA is a left-handed double helix - ✔✔Z-DNA
which of the following catalyzes the synthesis of ribosomal RNA in eukaryotes - ✔✔both RNA
polymerase I and III
, DNA strands are considered antiparallel because the strands are oriented in opposite directions. each
nucleotide strand has a 5'-3' or 3'-5' directionality. What is the basis of this DNA polynucleotide
directionality? - ✔✔the phosphodiester linkage points of the nucleotides: linking the 5' carbon and 3' -
OH group of each unit
bacterial mRNAs are polycistronic, whereas eukaryotic mRNAs are monocistronic. Polycistronic means
that - ✔✔bacterial mRNAs contain coding information for multiple genes
a cell biologist found that two different proteins with largely different structures were translated from
two different mRNAs. these mRNAs however were transcribed from the same gene in the cell nucleus.
which mechanism below could best account for this? - ✔✔exons from the same gene could be spliced in
different ways to make different mRNAs
different mRNA molecules can have poly(A) tails of different lengths and this affects the lifetime of the
mRNA molecule in the cell. Longer poly(A) tails means the mRNA is present for a greater time in the cell.
why do you think this is? - ✔✔the poly(A) tail protects the mRNA from being degraded by 3'
exonucleases
in humans, the cell that is fertilized by a sperm is the - ✔✔secondary oocyte
self-cleaving RNAs that function catalytically are called - ✔✔ribozymes
a rho-independent terminator - ✔✔forms a hairpin loop during termination
which of the following steps is responsible for the production of an active spliceosome during the
splicing of introns? - ✔✔dissociation of the U4 snRNP from the spliceosome complex is the activating
step leading to removal of the intron, the formation of a "lariat" and an mRNA with the intron spliced
out
the following figure shows the transcribed region of a typical eukaryotipicprotein coding gene. what is
the size in bases (bp) of the fully processed, mature mRNA? assume a poly(A) tail of 200 A's in
calculations - ✔✔376
(200 A's, + 100 + 50 + 25 exon bps)
Questions | 100% Correct Answers |
Verified 2024 Version
which of the following statements regarding a DNA double helix is always true? - ✔✔the amount of
adenine is equal to the amount of thymine, and the amount of guanine is equal to the amount of
cytosine
working in a coroner's office, you are investigating the mysterious death of a person found in the
wooded area in the spring of the year. during a cellular analysis of this body, you learn that the levels of
mRNA that can be obtained from critical tissues are very low, and you find mushrooms in the contents of
the stomach. after examination of the mushrooms, you learn that they are a species of Aminita, and a
search of the Internet reveals that a toxin in this fungus inhibits RNA polymerase. However this isn't very
specific information. to be more certain of the cause of death in this case, you would need to verify that
the alpha-aminitin inhibits which eukaryotic RNA polymerase? - ✔✔RNA polymerase II
a prokaryotic mRNA transcript is - ✔✔translated as it is being transcribed
in eukaryotes, transcription is initiated by the formation of a pre initiation complex of transcription
factors and RNA polymerase at the TATA box of the promoter. give the correct order of the steps below: -
✔✔A: the TFIID complex containing the TATA box binding proteins binds to the TATA box
B: TFIIA and TFIIB bind to the initiation complex
E: TFIIF binds to RNA polymerase and this complex adds to the complex assembling at the TATA box
D: TFIIE and TFIIH bind to the complex, and the helicase function of TRIIH produces a small bubble in the
double-stranded DNA
C: RNA polymerase begins transcribing the sense strand of the DNA producing a complementary RNA
which form of DNA is a left-handed double helix - ✔✔Z-DNA
which of the following catalyzes the synthesis of ribosomal RNA in eukaryotes - ✔✔both RNA
polymerase I and III
, DNA strands are considered antiparallel because the strands are oriented in opposite directions. each
nucleotide strand has a 5'-3' or 3'-5' directionality. What is the basis of this DNA polynucleotide
directionality? - ✔✔the phosphodiester linkage points of the nucleotides: linking the 5' carbon and 3' -
OH group of each unit
bacterial mRNAs are polycistronic, whereas eukaryotic mRNAs are monocistronic. Polycistronic means
that - ✔✔bacterial mRNAs contain coding information for multiple genes
a cell biologist found that two different proteins with largely different structures were translated from
two different mRNAs. these mRNAs however were transcribed from the same gene in the cell nucleus.
which mechanism below could best account for this? - ✔✔exons from the same gene could be spliced in
different ways to make different mRNAs
different mRNA molecules can have poly(A) tails of different lengths and this affects the lifetime of the
mRNA molecule in the cell. Longer poly(A) tails means the mRNA is present for a greater time in the cell.
why do you think this is? - ✔✔the poly(A) tail protects the mRNA from being degraded by 3'
exonucleases
in humans, the cell that is fertilized by a sperm is the - ✔✔secondary oocyte
self-cleaving RNAs that function catalytically are called - ✔✔ribozymes
a rho-independent terminator - ✔✔forms a hairpin loop during termination
which of the following steps is responsible for the production of an active spliceosome during the
splicing of introns? - ✔✔dissociation of the U4 snRNP from the spliceosome complex is the activating
step leading to removal of the intron, the formation of a "lariat" and an mRNA with the intron spliced
out
the following figure shows the transcribed region of a typical eukaryotipicprotein coding gene. what is
the size in bases (bp) of the fully processed, mature mRNA? assume a poly(A) tail of 200 A's in
calculations - ✔✔376
(200 A's, + 100 + 50 + 25 exon bps)
