CCTC CERTIFICATION REVIEW | 100% Correct
Answers | Verified | Latest 2024 Version
Absolute Contraindications for liver transplant - ✔✔Severe cardiopulmonary disease, uncontrolled HIV,
poorly controlled Psych illness, noncompliance, anatomical abnormalities precluding adequate surgical
reconstruction
Reason for not accepted for liver TX - ✔✔Hepatocellular Carcinoma (HCC) outside Milan Criteria
What is NAFLD? - ✔✔Nonalcoholic Fatty Liver Disease- caused by obesity, hyperglycemia, elevated
serum lipids, and high BP
What is NASH? - ✔✔Non-alcoholic steatohepatitis. Can lead to cirrhosis 3rd common indication for liver
TX.
What is the MELD score? - ✔✔MELD(Model for End Stage Liver Disease) is a predictive model of death
within a 3 month period. Ranks your degree of sickness, shows how much you need a liver transplant.
The higher the number, the more urgent case is. Score ranges from 6-40.
*Score for HCC capped at 34.
Calculated using:
-INR
-Bilirubin
-Creatinine
-Sodium
MELD > 14 needed for liver transplant
What can green drainage post liver TX indicate? - ✔✔Bile leakage
, What can a rise in ALP post liver tx indicate? - ✔✔Can be a sign of biliary complications or cholestasis
Lab changes are indicate of graft dysfunction. Which values will be elevated for liver tx? - ✔✔Elevated
AST and ALT
Target levels for immunosuppressants are based on a number of factors including: - ✔✔Indication for tx,
use of induction therapy, kidney function, overall condition of pt.
What can lead to metabolic encephalopathy post liver transplant? - ✔✔Renal failure or sepsis
What can lead to hypoxic ischemic encephalopathy post liver transplant? - ✔✔Significant peri-operative
hypotension
De Novo seizures can occur post liver transplant and can be caused by what? - ✔✔Electrolyte
imbalances, reaction to cyclosporine or tacrolimus, intracranial hemorrhage or cerebral infarction and
intracerebral abscesses
What can cause a post liver transplant patient whose initial postop neurological course is normal to
develop sudden deterioration in neurological status? - ✔✔Intracranial bleed
Risk of primary non-function after liver transplant is: - ✔✔4-6%
Factors related to primary nonfunction of new liver include: - ✔✔Donor age, prolonged cold ischemic
time, prolonged donor hospital stay with periods of hypotension, preservation injury during donor
surgery, and donor steatosis(fat in liver)
Early Indicators of non functioning liver: - ✔✔decrease in bile production
extreme edema of organ
Abnormal color of organ upon reperfusion(mottled, gray, pale)
lack of reperfusion in OR
urine output <30ml/hr
Answers | Verified | Latest 2024 Version
Absolute Contraindications for liver transplant - ✔✔Severe cardiopulmonary disease, uncontrolled HIV,
poorly controlled Psych illness, noncompliance, anatomical abnormalities precluding adequate surgical
reconstruction
Reason for not accepted for liver TX - ✔✔Hepatocellular Carcinoma (HCC) outside Milan Criteria
What is NAFLD? - ✔✔Nonalcoholic Fatty Liver Disease- caused by obesity, hyperglycemia, elevated
serum lipids, and high BP
What is NASH? - ✔✔Non-alcoholic steatohepatitis. Can lead to cirrhosis 3rd common indication for liver
TX.
What is the MELD score? - ✔✔MELD(Model for End Stage Liver Disease) is a predictive model of death
within a 3 month period. Ranks your degree of sickness, shows how much you need a liver transplant.
The higher the number, the more urgent case is. Score ranges from 6-40.
*Score for HCC capped at 34.
Calculated using:
-INR
-Bilirubin
-Creatinine
-Sodium
MELD > 14 needed for liver transplant
What can green drainage post liver TX indicate? - ✔✔Bile leakage
, What can a rise in ALP post liver tx indicate? - ✔✔Can be a sign of biliary complications or cholestasis
Lab changes are indicate of graft dysfunction. Which values will be elevated for liver tx? - ✔✔Elevated
AST and ALT
Target levels for immunosuppressants are based on a number of factors including: - ✔✔Indication for tx,
use of induction therapy, kidney function, overall condition of pt.
What can lead to metabolic encephalopathy post liver transplant? - ✔✔Renal failure or sepsis
What can lead to hypoxic ischemic encephalopathy post liver transplant? - ✔✔Significant peri-operative
hypotension
De Novo seizures can occur post liver transplant and can be caused by what? - ✔✔Electrolyte
imbalances, reaction to cyclosporine or tacrolimus, intracranial hemorrhage or cerebral infarction and
intracerebral abscesses
What can cause a post liver transplant patient whose initial postop neurological course is normal to
develop sudden deterioration in neurological status? - ✔✔Intracranial bleed
Risk of primary non-function after liver transplant is: - ✔✔4-6%
Factors related to primary nonfunction of new liver include: - ✔✔Donor age, prolonged cold ischemic
time, prolonged donor hospital stay with periods of hypotension, preservation injury during donor
surgery, and donor steatosis(fat in liver)
Early Indicators of non functioning liver: - ✔✔decrease in bile production
extreme edema of organ
Abnormal color of organ upon reperfusion(mottled, gray, pale)
lack of reperfusion in OR
urine output <30ml/hr
