Enzymology Exam 1 study guide
Which of these statements is correct?
A) A catalyst decreases the activation barrier by different amounts for the forward and
reverse reactions.
B) A catalyst decreases the activation barrier by the same amount for both the forward and
reverse reactions.
C) A catalyst increases the activation barrier by different amounts for the forward and
reverse reactions.
D) A catalyst increases the activation barrier by the same amount for both the forward and
reverse reactions.
E) A catalyst does not affect the activation barrier. - correct answer-B
Which of the following(s) are true about enzymes?
a. they alter free energy for the reaction
b. they decelerate the rate of the reaction
c. they decrease the activation energy of a reaction
d. they are all catalysts
e. they are complementary to substrates - correct answer-c
How many classes of an enzymes are there?
A. 3
B. 3
C.2
D. 6
E. A&B - correct answer-D
Enzymes can accelerate the rate of the reaction through ____:
1. Increasing Entropy
2. Decreasing Entropy
3. Decreasing Gibbs free energy of reaction
a. 1
b. 1 and 3
c. 2
d. 2 and 3 - correct answer-C
A catalyst lowers the activation barrier by:
A) different amounts for the forward and reverse reactions
B) the same amount for the forward and reverse reactions
C) only affecting the forward reaction
D) only affecting the reverse reaction - correct answer-B
The transition state of a catalyzed reaction is:
A) lower in energy than that of an uncatalyzed reaction
B) lower in energy than the reaction substrate
C) bound very weakly to the catalyst
,D) a highly-populated intermediate on the reaction pathway - correct answer-A
What gives an enzyme their distinctive shape?
A) Amino Acid Sequence
B)Coenzymes
C)Inhibitor formation
D)Competitive Inhibitor - correct answer-A
A legendary UoP professor wants to find out if enzyme workerase or lazierase is the most
efficient of the two, how should the legendary professor calculate the efficiency of the two
enzymes?
A) The difference between delta G for the uncatalyzed and catalyzed reactions
B) The difference between the reaction coordinates for the product and reactants
C) The difference between the free energy of the reaction from before adding the enzyme
and after
D) The difference between delta G of the substrate ground state and the product ground
state
E) Calculating the efficiency is impossible, you have to guess based on the name - correct
answer-A
What would happen to a chemical reaction when an enzyme is added?
A. The free energy of the reaction is lowered
B. The rate of the reaction is accelerated
C. The activation energy of the reaction increases
D. Delta G of the reaction is changed
E. The entropy of the reaction increases - correct answer-B
Which of the following statements is/are true?
A. Enzymes do not change the free energy
B. Enzymes affect free energy
C. Enzymes speed up the rate of a reaction
D. A & C
E. B & C - correct answer-D. A & C
When delta G‡ increases in the rate-determining step, what is the effect on the rate of
reaction?
A. Increases
B. Decreases
C. No change - correct answer-B
Free energy is most available at what point in the reaction?
A. Reactant ground state
B. Product ground state
C. After product is made
D. During the transition state
E. Free energy is always the same - correct answer-D
What do enzymes do?
, A. Change free energy
B. Change the equilibrium
C. Accelerate the rate of reaction
D. Alter delta G for the reaction - correct answer-C
How do enzymes differ from chemical catalysts?
A) Capacity for regulation
B) Slower reaction rates
C) Greater reaction specificity
D) Harsher reaction conditions
E) Both A and C - correct answer-E. A & C
Substrate binding allows?
A. Entropy reduction
B. Desolvation of substrate
C. Formation of strong interactions
D. A & B
E. B & C - correct answer-D. A & B
A negative delta G would mean what for the reaction?
A. The reaction is spontaneous
B. The reaction is not spontaneous
C. The reaction is at equilibrium
D. The reaction can always take place
E. The reaction can never take place - correct answer-A
enzymes ____the ____ of a reaction
A accelerate, rate
B increase, entropy
C stop, rate
D decrease, rate
E decrease, energy - correct answer-A
The point of _________ energy is called the transition state
A. highest free
B. lowest free
C. highest confined
D. lowest constant
E. highest constant - correct answer-A
Which of the following are true about enzymes?
A. Free energy predicts the spontaneity of a reaction.
B. Enzymes do not change free energy.
C. Enzymes accelerate the rate of the reaction.term-23
D. Enzymes decelerate the rate of the reaction.
E. More than one of the choices. - correct answer-E
Which of the following is not included in the EC number
Which of these statements is correct?
A) A catalyst decreases the activation barrier by different amounts for the forward and
reverse reactions.
B) A catalyst decreases the activation barrier by the same amount for both the forward and
reverse reactions.
C) A catalyst increases the activation barrier by different amounts for the forward and
reverse reactions.
D) A catalyst increases the activation barrier by the same amount for both the forward and
reverse reactions.
E) A catalyst does not affect the activation barrier. - correct answer-B
Which of the following(s) are true about enzymes?
a. they alter free energy for the reaction
b. they decelerate the rate of the reaction
c. they decrease the activation energy of a reaction
d. they are all catalysts
e. they are complementary to substrates - correct answer-c
How many classes of an enzymes are there?
A. 3
B. 3
C.2
D. 6
E. A&B - correct answer-D
Enzymes can accelerate the rate of the reaction through ____:
1. Increasing Entropy
2. Decreasing Entropy
3. Decreasing Gibbs free energy of reaction
a. 1
b. 1 and 3
c. 2
d. 2 and 3 - correct answer-C
A catalyst lowers the activation barrier by:
A) different amounts for the forward and reverse reactions
B) the same amount for the forward and reverse reactions
C) only affecting the forward reaction
D) only affecting the reverse reaction - correct answer-B
The transition state of a catalyzed reaction is:
A) lower in energy than that of an uncatalyzed reaction
B) lower in energy than the reaction substrate
C) bound very weakly to the catalyst
,D) a highly-populated intermediate on the reaction pathway - correct answer-A
What gives an enzyme their distinctive shape?
A) Amino Acid Sequence
B)Coenzymes
C)Inhibitor formation
D)Competitive Inhibitor - correct answer-A
A legendary UoP professor wants to find out if enzyme workerase or lazierase is the most
efficient of the two, how should the legendary professor calculate the efficiency of the two
enzymes?
A) The difference between delta G for the uncatalyzed and catalyzed reactions
B) The difference between the reaction coordinates for the product and reactants
C) The difference between the free energy of the reaction from before adding the enzyme
and after
D) The difference between delta G of the substrate ground state and the product ground
state
E) Calculating the efficiency is impossible, you have to guess based on the name - correct
answer-A
What would happen to a chemical reaction when an enzyme is added?
A. The free energy of the reaction is lowered
B. The rate of the reaction is accelerated
C. The activation energy of the reaction increases
D. Delta G of the reaction is changed
E. The entropy of the reaction increases - correct answer-B
Which of the following statements is/are true?
A. Enzymes do not change the free energy
B. Enzymes affect free energy
C. Enzymes speed up the rate of a reaction
D. A & C
E. B & C - correct answer-D. A & C
When delta G‡ increases in the rate-determining step, what is the effect on the rate of
reaction?
A. Increases
B. Decreases
C. No change - correct answer-B
Free energy is most available at what point in the reaction?
A. Reactant ground state
B. Product ground state
C. After product is made
D. During the transition state
E. Free energy is always the same - correct answer-D
What do enzymes do?
, A. Change free energy
B. Change the equilibrium
C. Accelerate the rate of reaction
D. Alter delta G for the reaction - correct answer-C
How do enzymes differ from chemical catalysts?
A) Capacity for regulation
B) Slower reaction rates
C) Greater reaction specificity
D) Harsher reaction conditions
E) Both A and C - correct answer-E. A & C
Substrate binding allows?
A. Entropy reduction
B. Desolvation of substrate
C. Formation of strong interactions
D. A & B
E. B & C - correct answer-D. A & B
A negative delta G would mean what for the reaction?
A. The reaction is spontaneous
B. The reaction is not spontaneous
C. The reaction is at equilibrium
D. The reaction can always take place
E. The reaction can never take place - correct answer-A
enzymes ____the ____ of a reaction
A accelerate, rate
B increase, entropy
C stop, rate
D decrease, rate
E decrease, energy - correct answer-A
The point of _________ energy is called the transition state
A. highest free
B. lowest free
C. highest confined
D. lowest constant
E. highest constant - correct answer-A
Which of the following are true about enzymes?
A. Free energy predicts the spontaneity of a reaction.
B. Enzymes do not change free energy.
C. Enzymes accelerate the rate of the reaction.term-23
D. Enzymes decelerate the rate of the reaction.
E. More than one of the choices. - correct answer-E
Which of the following is not included in the EC number
