| 2024 Version
The only nutrient deficiency that is also prevalent in Industrialized counties - ✔✔Iron
Iron deficiency's effect on Transferrin - ✔✔increases transferrin synthesis and total iron binding capacity
Physical symptoms in severe IDA - ✔✔Reduced work capacity and breathlessness on exertion
What exacerbates anemia - ✔✔Infectious diseases such as malaria and worm infections
What interferes with iron absorption? - ✔✔Phytates, this is an issue in lower income countries as most
of the iron consumed is plant based that also has phytates
Why do women absorb more iron? - ✔✔Because they have lower stores
Sources of nonheme iron - ✔✔Dark leafy greens
What enhances iron absorption? - ✔✔Protein and ascorbic acid
Primary use of stored iron? - ✔✔Production of hemoglobin
Full-term infants are iron stores - ✔✔Born with substantial iron stores that will last about 6 months
(preterm or LBW, only 2-3 months). This is when iron rich complementary foods should be introduced
Why is more iron required during periods of growth? - ✔✔As the blood volume expands, the iron
requirement grows. It can be difficult to maintain this positive balance.
, Iron absorption, cows milk v. breast milk - ✔✔Although cows milk has more iron only 10% of it can be
absorbed while 50% of iron in breast milk can be
Hookworm and Iron - ✔✔In tropical counties hookworm is a major cause of gastrointestinal blood loss,
contributing to deficiency in older children and adults
Serum Iron Concentration - ✔✔Not a great way to determine anemia, measures serum iron and is
reduced by inflammation, malignancy, and during menstruation.
Total Iron Binding Capacity - ✔✔Test for iron deficiency, TIBC is raised in iron deficiency.
Transferrin Saturation - ✔✔Test for iron deficiency, ratio of serum iron and TIBC, decreased in iron
deficiency
Serum Ferritin - ✔✔Test for iron deficiency, reflects the status of total body iron stores. Low value
indicates anemia. Test of choice!
Problem with Serum Ferritin test - ✔✔Inflammation and infection rise levels and can hide deficiency
Universal supplimentation of Iron - ✔✔Great where iron deficiencies are very common. Give out
supplements to all!
Ferrous Sulphate - ✔✔Highly soluble form of iron used to fortify infant formula and bread
Regions with iodine deficiency - ✔✔Mountainous and river deltas
What industrial country was discovered to be mildly iodine deficient in the 2000's - ✔✔Australia
Goitrogens - ✔✔Substances that compete with iodine uptake, found in maize, sweet potatoes, lima
beans