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FNDH 400 Exam 3 100% Correct Verified 2024 Version

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Where does the name Vitamin come from? - Vital amines -- Vitamines, but when it was discovered they weren't amines, the E was dropped Fat soluble vitamins - A, D, E, K Water Soluble Vitamins - C, B What B vitamin numbers are missing? Why? - B4, B8, B10, B11 Were discovered and then removed due to redudancy EV McCollum and vitamins - Theorized fat-soluble factor A that deficiency led to ophthalmia (inflammation of the eye) and water-soluble factor B resulted in beriberi Factor A -- Vitamin A Factor B -- B1 and B2 (realized there were multiple B2s) Thiamin cofactor - Thiamin Pyrophosphate (TPP) Riboflavin cofactor - Flavin Adenine Dinucleotide (FAD) Flavin Mononucleotide (FMN) Niacin cofactor - Nicotine Adenine Dinucleotide (NAD) Nicotine Adenine Dinucleotide Phosphate (NADP) Pantothenic Acid cofactor - Coenzyme AVitamin B6 cofactor - Pyridoxal Phosphate (PLP) Folate cofactor - Tetrahydrofolate (THF) Vitamin B12 cofactor - Adensosylcobalamin Methylcobalamin Most cofactors come from ___ vitamins - B Why must we consume B vitamins? - Cofactors Mineral amount classifcation - Amount required Macromineral Trace Minerals Ultratrace Minerals DRIs - EAR RDA AI UL Dietary guideliens - Qualitative advice to the public about diet and chronic disease prevention and health maintenance DRI definition - Quantitative advice to professionals about amounts of nutrients or food components to be of benefit Dietary guidelines vs DRI - Qualitative for public vs. Quantitative for professionals RDA (Definition, Needs met, Set) - Recommended Dietary AllowanceAsses quality of people's diets Meets needs of 97.5% of the population Calculated using EAR (EAR + 2 standard deviations) EAR (Definition, Needs met, Set) - Estimated Average Requirement Estimated quality of 50% of the population Requires applicable research Risk for inadequacy for EAR vs RDA - .5 (50%) EAR .025 (25%) RDA Formula for setting RDA - EAR + 2 standard deviations AI (Definition, Needs Met, Set) - Adequate Intake Level that appears to be adequate in a defined population or subgroup Not research based Used for groups researchers are hesitant to test on (Infants, Pregnant Women, etc.) UL (Definition, Needs Met, Set) - Tolerable Upper Intake Level Highest level of daily nutrient intake that is unlikely to pose risk of adverse health effects to almost all individuals of a population First sets a NOAEL and LOEAL and then UL set lower based on uncertainty factors NOAEL and LOAEL - No observed adverse effect level Lowest observed adverse effect level *Note: Not DRI components, just measures needed for UL

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FNDH 400 Exam 3 | 100% Correct | Verified |
2024 Version
Where does the name Vitamin come from? - ✔✔Vital amines --> Vitamines, but when it was discovered
they weren't amines, the E was dropped



Fat soluble vitamins - ✔✔A, D, E, K



Water Soluble Vitamins - ✔✔C, B



What B vitamin numbers are missing? Why? - ✔✔B4, B8, B10, B11

Were discovered and then removed due to redudancy



EV McCollum and vitamins - ✔✔Theorized fat-soluble factor A that deficiency led to ophthalmia
(inflammation of the eye) and water-soluble factor B resulted in beriberi



Factor A --> Vitamin A

Factor B --> B1 and B2 (realized there were multiple B2s)



Thiamin cofactor - ✔✔Thiamin Pyrophosphate (TPP)



Riboflavin cofactor - ✔✔Flavin Adenine Dinucleotide (FAD)

Flavin Mononucleotide (FMN)



Niacin cofactor - ✔✔Nicotine Adenine Dinucleotide (NAD)

Nicotine Adenine Dinucleotide Phosphate (NADP)



Pantothenic Acid cofactor - ✔✔Coenzyme A

,Vitamin B6 cofactor - ✔✔Pyridoxal Phosphate (PLP)



Folate cofactor - ✔✔Tetrahydrofolate (THF)



Vitamin B12 cofactor - ✔✔Adensosylcobalamin

Methylcobalamin



Most cofactors come from ___ vitamins - ✔✔B



Why must we consume B vitamins? - ✔✔Cofactors



Mineral amount classifcation - ✔✔Amount required

Macromineral > Trace Minerals > Ultratrace Minerals



DRIs - ✔✔EAR

RDA

AI

UL



Dietary guideliens - ✔✔Qualitative advice to the public about diet and chronic disease prevention and
health maintenance



DRI definition - ✔✔Quantitative advice to professionals about amounts of nutrients or food components
to be of benefit



Dietary guidelines vs DRI - ✔✔Qualitative for public vs. Quantitative for professionals



RDA

(Definition, Needs met, Set) - ✔✔Recommended Dietary Allowance

, Asses quality of people's diets

Meets needs of 97.5% of the population

Calculated using EAR (EAR + 2 standard deviations)



EAR

(Definition, Needs met, Set) - ✔✔Estimated Average Requirement

Estimated quality of 50% of the population

Requires applicable research



Risk for inadequacy for EAR vs RDA - ✔✔.5 (50%) EAR

.025 (25%) RDA



Formula for setting RDA - ✔✔EAR + 2 standard deviations



AI

(Definition, Needs Met, Set) - ✔✔Adequate Intake

Level that appears to be adequate in a defined population or subgroup

Not research based

Used for groups researchers are hesitant to test on (Infants, Pregnant Women, etc.)



UL

(Definition, Needs Met, Set) - ✔✔Tolerable Upper Intake Level

Highest level of daily nutrient intake that is unlikely to pose risk of adverse health effects to almost all
individuals of a population

First sets a NOAEL and LOEAL and then UL set lower based on uncertainty factors



NOAEL and LOAEL - ✔✔No observed adverse effect level

Lowest observed adverse effect level

*Note: Not DRI components, just measures needed for UL

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