2024
What is holocrine? **** whole cell is secreted (except sebaceous gland)
What is apocrine? **** Apex of cell is secreted
What is merocrine? **** cell is maintained - exocytosis
What is paracrine? **** Works on it's neighbor (except sweat gland)
What is autocrine? **** Works on itself (except T-cell activation)
what does exocrine mean? **** secreted into a duct
what does endocrine mean? **** secreted into the blood
what are the 5 steroid hormones? **** testosterone
estrodiol (E2)
progesterone
aldosterone
cortisol
What receptors do steroid hormones use? **** Nuclear membrane receptors (except
cortisol -cytoplasmic receptor)
What receptors do protein hormones use? **** cell membrane receptors
what is a lactotrope **** Prolactin (PRL)
What is a corticotrope? **** ACTH
what is a thyrotrope? **** TSH
What is a gonadoptrope? **** LH & FSH
What is a somatotrope? **** growth hormone (GH)
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,what is karyolysis? **** nucleus dissolves
what is karyorrhexis? **** nuclear fragmentation
what is pyknosis? **** Nucleus turns into blobs "shrinkage"
what is apoptosis **** programmed cell death
no inflammation
cell membrane dissolved first
nucleus guides death & destroyed last
what is necrosis? **** non-programmed cell death
nucleus destroyed first
what organs do not require insulin to absorb glucose? **** "BRICKLE"
Brain
RBCs
Intestines
Cardiac/cornea
kidneys
liver
exercising muscle
what is the function of GnRH? **** Release gonadotropes - LH and FSH
what is the function of GRH? **** Stimulates GH release
What is the function of CRH? **** STimulates ACTH release
what is the function of TRH? **** stimulates TSH release
what is the function of PRH? **** Stimulates prolactin (PRL) release
What does somatostatin do? **** Inhibits GH release
What does anti-diuretic hormone do? **** Conserves water via V2 aquaporin
receptors & vasoconstriction
What does oxytocin do? **** milk letdown & uterine contractions (baby letdown)
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, What does growth hormone do? **** 1. stimulates insulin like growth factor (IGF-1)
release from the liver
2. stimulates growth
3. sends somatomedin to growth plates
4. Gluconeogenesis by proteolysis
What is the function of TSH? **** Stimulates release of T3 and T4 from the thyroid
What are the full names for T3 and T4? **** T3= triiodothyronine
T4= thyroxin
What is the function of LH on testes? **** stimulates testosterone release from
testes
what is the function of LH on the ovaries? **** stimulates the release of androgens
and progesterone from the ovary
what is the function of FSH in a male? **** sperm, MIF, inhibin B
what is the function of FSH in a female? **** stimulates estardiol (E2)
what is the function of prolactin? **** milk production
what is the function of ACTH? **** stimulates adrenal cortex to release cortisol &
androgen
what is the function of MSH? **** provides skin pigmentation
what are the stress hormones and when do they appear? **** Epinephrine-
immediately
Glucagon- 20 minutes
Insulin- 30 minutes
ADH- 30 minutes
Cortisol- 2-4 hours
GH- 24 hours
WHat is primary diabetes insipidus (DI)? **** Too much water (urinate a lot)
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