Summary Answering Technique for OSPE Pathology Questions

Answering Techniques for OSPE Pathology
questions


Describe the pathology (lesion/mass/haemorrhage)

1. Gross morphology
- What organ is it
- Where is the lesion (exact location)
o Corpus callosum
o Putamen
o Lentiform nucleus
- Localized or generalised
o Blood clot localized in lenticulostriate artery
o Neurocysticercosis is generalized in the patient’s brain
- Any deformities from the primary lesion
o Brain herniation
o Bowel ischemia
- Any new growth
o Polyps in the distal colon
o Cartilage cap on the bone spur
- Any colour change
o Red and inflamed distal colon
- Any size or shape changes (Compare to other organ if there is)
o Left testicular atrophy
o Hepatomegaly



2. Histopathology
- Eosinophilic or Basophilic
- Inflammatory cells infiltrate (which type)
o Polymorphonuclear cells infiltrate in acute inflammation
o Macrophages infiltrate in chronic inflammation
- Cells changes (morphology: metaplasia, dysplasia, neoplasia)
- Foreign body
o Granuloma
- Nucleus changes (pyknosis, karyorrhexis, karyolitic, bilobed)
- Cytoplasm ratio (increase N:C ratio in neoplasia)