MSP Test 1 Prep | Actual Exam Questions |
100% Correct Answers | Verified
2024 Version
most versatile type of connective tissue - ✔✔fibroblasts
what can fibroblast differentiate into? - ✔✔
-bone
-fat
-smooth muscle
-cartilage
when do fibroblast become cartilage? - ✔✔when in an enviornment without oxygen and cartilage is
avascular
when does cartilage become fibroblast - ✔✔when oxygen is introduced to the cartilage is morphs back
what cells produce type I collagen? - ✔✔
bone
fat
smooth muscle
what cells produce type II collagen? - ✔✔cartilage
least specialized cell in body - ✔✔fibroblasts
-allows it to morph easily
,what embryonic derivative are fibroblast - ✔✔mesodermal derivative
what do fibroblasts secrete? - ✔✔extracellular matrix
-collagen
-prosteoglycans
-elastin
-fibronectin and other structural proteins
what is collagen - ✔✔-present in almost all organs
-holds cells together
-gives tissue structural integrity
mammalian protein - ✔✔25% of all mammalian protein is collagen
signs and symptoms a patient with collagen synthesis disorder may present with - ✔✔-excessive
bleeding
-hypermobility
-joint laxity
-bone fragility
-slower healing time
sign vs. symptom - ✔✔sign- what doctor observes
symptom- what patient complains of
collagen synthesis stages - ✔✔1. intracellular stage
2. extracellular stage
, intracellular stage of collagen synthesis - ✔✔from amino acid synthesis to procollagen
extracellular stage of collagen synthesis - ✔✔from procollagen to mature collagen
what occurs in the rough ER - ✔✔mRNA transcription and translation
amino acid arrangement - ✔✔arranged into alpha-chains
sequence of amino acids - ✔✔genetically predetermined
critical in determining the collagen end product
amino acid chain composition - ✔✔repeating Gly - X - Y
-X and Y can be any other animo acid, but gylcine appears every 3rd
most common AA foun on X position of chain - ✔✔proline
common AA found in Y position of chain - ✔✔Hydroxyproline and Hydroxylysine
what do Imino acids do - ✔✔creates rigid cyclic structure that will limit the rotation of the chain
what two amino acids are Imino acids - ✔✔proline and hydroxyproline
smallest amino acid - ✔✔glycine
what gives the chain a helical structure - ✔✔glycine
100% Correct Answers | Verified
2024 Version
most versatile type of connective tissue - ✔✔fibroblasts
what can fibroblast differentiate into? - ✔✔
-bone
-fat
-smooth muscle
-cartilage
when do fibroblast become cartilage? - ✔✔when in an enviornment without oxygen and cartilage is
avascular
when does cartilage become fibroblast - ✔✔when oxygen is introduced to the cartilage is morphs back
what cells produce type I collagen? - ✔✔
bone
fat
smooth muscle
what cells produce type II collagen? - ✔✔cartilage
least specialized cell in body - ✔✔fibroblasts
-allows it to morph easily
,what embryonic derivative are fibroblast - ✔✔mesodermal derivative
what do fibroblasts secrete? - ✔✔extracellular matrix
-collagen
-prosteoglycans
-elastin
-fibronectin and other structural proteins
what is collagen - ✔✔-present in almost all organs
-holds cells together
-gives tissue structural integrity
mammalian protein - ✔✔25% of all mammalian protein is collagen
signs and symptoms a patient with collagen synthesis disorder may present with - ✔✔-excessive
bleeding
-hypermobility
-joint laxity
-bone fragility
-slower healing time
sign vs. symptom - ✔✔sign- what doctor observes
symptom- what patient complains of
collagen synthesis stages - ✔✔1. intracellular stage
2. extracellular stage
, intracellular stage of collagen synthesis - ✔✔from amino acid synthesis to procollagen
extracellular stage of collagen synthesis - ✔✔from procollagen to mature collagen
what occurs in the rough ER - ✔✔mRNA transcription and translation
amino acid arrangement - ✔✔arranged into alpha-chains
sequence of amino acids - ✔✔genetically predetermined
critical in determining the collagen end product
amino acid chain composition - ✔✔repeating Gly - X - Y
-X and Y can be any other animo acid, but gylcine appears every 3rd
most common AA foun on X position of chain - ✔✔proline
common AA found in Y position of chain - ✔✔Hydroxyproline and Hydroxylysine
what do Imino acids do - ✔✔creates rigid cyclic structure that will limit the rotation of the chain
what two amino acids are Imino acids - ✔✔proline and hydroxyproline
smallest amino acid - ✔✔glycine
what gives the chain a helical structure - ✔✔glycine
