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USABO Open Exam 2010.

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USABO Open Exam 2010
Both amino acids and nucleotides form complex chains. Select all the answers below that
are accurate.

A. The chains formed by both have polar phosphate groups.
B. Both contain peptide bonds.
C. Both contain nitrogen.
D. The chains formed by both can be lysed by trypsin.
E. The sequence of chains both form from preexisting templates. - correct answer-C. Both
contain nitrogen.
E. The sequence of chains both form from preexisting templates.

When a population is in Hardy-Weinberg equilibrium, which of the following is true?

A. All of its recessive lethal genes are wiped out, leaving only healthy dominant genes.
B. dN/dt = 0, N = population size.
C. Mutations occur at five times the normal rate to balance the loss of genes by way of
natural selection.
D. The frequencies of the alleles in the population change over time.
E. The frequencies of genotypes in the population are stable over time. - correct answer-E.
The frequencies of genotypes in the population are stable over time.

Which of the following is NOT an accurate description of protein synthesis and folding?

A. All protein synthesis is initiated in the cytoplasm.
B. Many copies of a protein can be synthesized simultaneously from the same mRNA.
C. The 3D shape of a protein is determined largely by its amino acid sequence.
D. The entire chain of amino acids exits the ribosome before it begins folding into its 3D
shape.
E. The first encoded amino acid in every protein is methionine. - correct answer-C. The 3D
shape of a protein is determined largely by its amino acid sequence.

Neurotransmitter released at the synapse binds to two classes of receptors. Select the
correct response(s).

A. Metabotropic receptors that do not form an ion pore are linked with signal transduction
mechanisms and can alter neuron function for seconds to minutes.
B. Receptor tyrosine kinases that activate signal transduction mechanisms and change gene
transcription that can last for hours to days.
C. Ionotropic receptors that do not form an ion pore are linked with signal transduction
mechanisms and can alter neuron function for seconds to minutes.
D. Ionotropic receptors that are directly linked to an ion pore and are opened within
milliseconds in response to neurotransmitter.
E. Steroid hormone receptors that can activate changes in gene transcription that can last
for hours to days. - correct answer-A. Metabotropic receptors that do not form an ion pore

, are linked with signal transduction mechanisms and can alter neuron function for seconds to
minutes.
D. Ionotropic receptors that are directly linked to an ion pore and are opened within
milliseconds in response to neurotransmitter.

Many proteins are transported around cells in vesicles. Which of the following determines
the specificity or directionality of vesicle transport?

A. Clathrin coat proteins.
B. v-SNARES and t-SNARES.
C. Flippase.
D. Myristoylation.
E. Hydrophobic domains. - correct answer-B. v-SNARES and t-SNARES.

The primary energy source of the brain is

A. Arabinose.
B. Creatine.
C. Fructose.
D. Glucose.
E. L-serine. - correct answer-D. Glucose.

Which set of the following statements are correct?
1. Osmosis can be used to measure the molecular weight of macromolecules.
2. Aquaporins affect the rate of water transport across membranes.
3. Antidiuretic hormone (ADH) controls aquaporins and the reabsorption of water in the
kidney.
4. Reverse osmosis is a process that uses a pressure greater than the osmotic pressure to
force the solvent through a semi-permeable membrane from the side with a high solute
concentration.
5. Passive proton pumps in plant cell membranes establish proton gradients.

A. Only statements 2, 3 & 4 are correct.
B. Only statements 5, 2 & 3 are correct.
C. Only statements 1, 2 & 3 are correct.
D. Only statements 1, 2, 3, & 4 are correct.
E. All statements are correct. - correct answer-D. Only statements 1, 2, 3, & 4 are correct.

If two animals with the genotype AaBb X AaBb are mated, what is the probability of
generating an offspring with the genotype AABb? Assume there is no linkage between the
two genes.

A. 1/8
B. 1/4
C. 3/8
D. 1/2
E. 5/8 - correct answer-A. 1/8

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