Doxy and PrEP for the condomless sex: Pharm III Exam I Complete Questions And Answers A+

Which of the following is NOT an AIDS-defining condition per the CDC?
A. Pneumocystis pneumonia
B. Kaposi Sarcoma
C. Oral Hairy Leukoplakia
D. HIV-related encephalopathy
C. Oral Hairy Leukoplakia


T/F HIV-2 is more widespread, whereas HIV-1 is most commonly seen in West
Africa
False, HIV-1 is more widespread, whereas HIV-2 is most commonly seen in
West Africa




Which of the following patients who is HIV positive meets diagnostic criteria
for Acquired-Immunodeficiency Syndrome?
A. A patient with a CD4 count of 320 cells/mm3
B. A patient with a CD4 cell as 13% of their total lymphocytes
C. A patient with oral hairy leukoplakia
D. A patient with a CD4 count of 300, with CD4 T-cells composing 15% of their
total lymphocytes
B. A patient with a CD4 cell as 13% of their total lymphocytes


'
T/F HIV viral load is measured by HIV RNA Quantification
True


What is the most common mechanism of HIV transmission?
A. Vertical transmission (mother to child)
B. IV drug use
C. Receptive anal or vaginal intercourse
D. Iatrogenic (blood products, transfusions, organ transplant)
C. Receptive anal or vaginal intercourse


HIV life cycle consists of 7 stages: binding, fusion, reverse transcription,
integration, replication, assembly, and budding. Protease inhibitors act on
which stage of the viral life cycle?
A. Binding
B. Reverse Transcription
C. Integration

,D. Budding
D. Budding


HIV life cycle consists of 7 stages: binding, fusion, reverse transcription,
integration, replication, assembly, and budding. Integrase inhibitors act on
which stage of the viral life cycle?
A. Binding
B. Reverse Transcription
C. Integration
D. Budding
C. Integration


HIV life cycle consists of 7 stages: binding, fusion, reverse transcription,
integration, replication, assembly, and budding. NRTIs act on which stage of
the viral life cycle?
A. Binding
B. Reverse Transcription
C. Integration
D. Budding
B. Reverse Transcription - NNRTI (non-nucleoside reverse transcriptase
inhibitor) NRTI (nucleoside reverse transcriptase inhibitor) both act on this
step


HIV life cycle consists of 7 stages: binding, fusion, reverse transcription,
integration, replication, assembly, and budding. CCR5 antagonists act on
which stage of the viral life cycle?
A. Binding
B. Reverse Transcription
C. Integration
D. Budding
A. Binding


Which of the following therapeutics is a fusion inhibitor?
A. Enfuvirtide
B. Ibalizumab
C. Ritonavir
D. Cobicistat
A. Enfuvirtide - one of two therapeutics that are the ONLY options approved for
use in treatment-experienced patients with drug resistance

,Which of the following therapeutics is a CD4 post attachment inhibitor?
A. Enfuvirtide
B. Ibalizumab
C. Ritonavir
D. Cobicistat
B. Ibalizumab - one of two therapeutics that are the ONLY options approved for
use in treatment-experienced patients with drug resistance


Which of the following therapeutics is a regimen booster, acting as a protease
inhibitor with antiviral activity?
A. Enfuvirtide
B. Ibalizumab
C. Ritonavir
D. Cobicistat
C. Ritonavir


Which of the following therapeutics is a regimen booster, acting as a CYP3A4
inhibitor without antiviral activity?
A. Enfuvirtide
B. Ibalizumab
C. Ritonavir
D. Cobicistat
D. Cobicistat - structural analogue of ritonavir


Which of the following combination therapies for the treatment of HIV is
inappropriate?
A. Two NRTIs + INSTI
B. INSTI monotherapy
C. Two NRTIs + PI + enhancer
D. Two NRTIs + NNRTI
B. INSTI monotherapy monotherapy is never recommended. Two-drug regimes
may be supported for initial therapy in special circumstances


Abacavir, Emtricitabine, Lamivudine, Tenofovir disoproxil fumarate, Tenofovir
alafenamide, and Zidovudine all belong to which class of antiviral
medications?
A. Nucleoside reverse transcriptase inhibitors
B. Non-nucleoside reverse transcriptase inhibitors
C. Protease inhibitors

, D. Fusion inhibitors
A. Nucleoside reverse transcriptase inhibitors (NTRI)


Doravine, efavirenz, etravirine, nevirapine, and rilpivirine all belong to which
class of antiviral medications?
A. Nucleoside reverse transcriptase inhibitors
B. Non-nucleoside reverse transcriptase inhibitors
C. Protease inhibitors
D. Fusion inhibitors
B.Non-nucleoside reverse transcriptase inhibitors


Atazanavir, darunavir, and ritonavir all belong to which class of antiviral
medications?
A. Nucleoside reverse transcriptase inhibitors
B. Non-nucleoside reverse transcriptase inhibitors
C. Protease inhibitors
D. Fusion inhibitors
C. Protease inhibitors


Ibalizumab and fostemsavir belong to which class of antiviral medications?
A. CD4 post attachment inhibitors
B. CCR5 antagonist
C. Integrase inhibitors
D. Fusion inhibitors
A. CD4 post attachment inhibitors


Maraviroc belongs to which class of antiviral medications?
A. CD4 post attachment inhibitors
B. CCR5 antagonist
C. Integrase inhibitors
D. Fusion inhibitors
B. CCR5 antagonist


Dolutegravir belongs to which class of antiviral medications?
A. CD4 post attachment inhibitors
B. CCR5 antagonist
C. Integrase inhibitors
D. Fusion inhibitors
C. Integrase inhibitors