PHARM DRUGS CHAPTER 4 QUESTIONS WITH 100% CORRECT ANSWERS { GRADED A+}

PHARM DRUGS CHAPTER 4

QUESTIONS WITH 100% CORRECT

ANSWERS { GRADED A+}




what two drugs interact with the cholinergic terminals? - ✔✔botulinum

toxins and hemicholiniums


what does hemicholinium do - ✔✔Inhibit *choline* transport by

inhibiting Na+/Choline co-transporter so NO ACH release


what does botulinium toxin do - ✔✔breaks down SNAPS and VAMPS on

cholinergic channels so no ACH produced (which is what tells muscles

to contract- so no wrinkles)


what do cholinergic drugs do? - ✔✔Mimic parasympathetic nervous

system

, Will increase acetylcholine


what are the two types of cholinergic drugs - ✔✔direct acting and

indirect acting

cholinergic drugs effects are predictable based on what characteristics -

✔✔DUMBELLS


name a cholinergic direct drug - ✔✔varenicline


what does varenicline do - ✔✔partial agonist of a4B2 receptor

(nueronal nicotinic subunit)

decreases stimulation from parasympathetic nervous system; smoking

cessation aid


what receptor is typically binded to for addiction - ✔✔a4b2


what is the risk of varenicline - ✔✔mania and suicidal ideation


name the indirect cholinergic drugs - ✔✔neostigmine and

pyridostigmine and malathion