ANSWERS AND CORRECT QUESTIONS
GRADED A+ 2024-2025 (LATEST)
Cholinesterase inhibitors - ANS-Donepezil
Rivastigmine
Galantamine
neostigmine
Cholinesterase inhibitors side effects - ANS-dizziness, GI upset, fatigue, headache
cholinesterase inhibitors adverse affects - ANS-bradycardia bronchoconstriction
cholinesterase inhibitors interactions - ANS-Anticholinergics, first generation anithistamines, TCA's,
conventional antipsychotics
Donzepil side effects - ANS-nausea vomitting diarrhea urinary urgency bronchoconstriction bradycardia
orthostatic hypotension
rivastigmine - ANS-side effects likely and more intense. caution with PUD bradycardia sick sinus
syndrome urinary obstruction, lung disease. transdermal route lowers intensity of side effects.
, neostigmine - ANS-prevents acetylcholine degradation. myasthenia gravis, parkinsons dementia,
alzheimers
Galantamine - ANS-caution use in asthma or copd . avoid anticholinergics 1st gen antihistamines, TCAs,
conventional antipsychotics because they reduce effects.
nmda blocker - ANS-antagonist.
Memantime - ANS-NMDA blocker
Memantime adverse reactions - ANS-skin reactions. steven johnsons syndrome. erythema multiforme.
bradycardia, hypertensions, angina.
Memantime side effects - ANS-dizziness headache confusion diarrhea or constipation
Immunomodulators - ANS-interferon beta
interferon beta - ANS-FLu like symptoms, hepatotoxicity, myelosuppression (decreases all blood cells
monistor cbc frequently) injection site reaction. depressions
interferon beta drug interactions - ANS-other immunosuppressive drugs
immunosuppressants - ANS-Mitoxantrone
mitoxantrone - ANS-decreases autoimmune destruction of myelin.
Mitoxantrone side effects - ANS-myelosuppression(montior cbc) increased risk for infections. no live
virus immunizations. cardiotoxicity (irreverisble damage to ejection fraction) fetal harm (growth delay
and prematurity)