week 1 Quiz With Questions And Correct Detailed
Answers 2024-2025 Updated
Pharmacokinetics - ANSWER---The study of drug absorption, distribution,
metabolism, and excretion in the body
"What the body does to the drug"
Factors that affect drug absorption (5) - ANSWER---Rate of dissolution
Surface area
Blood flow
Lipid solubility
PH partitioning
Factors that affect drug distribution (4) - ANSWER---Blood flow to tissues
Ability to exit vascular system
Blood-brain barrier
Protein-binding capacity
Pharmacodynamics - ANSWER---The study of biochemical and physiologic effects
of drugs on the body and the molecular mechanisms by which those effects are
produced
"What the body does to the drug"
Phamacodynamics: 3 mechanisms of action - ANSWER---Receptor
Enzyme
Non-selective interactions (i.e. chemo)
,Nr 565 / Nr565 advanced pharmacology fundamentals
week 1 Quiz With Questions And Correct Detailed
Answers 2024-2025 Updated
Types of drug therapy (7) - ANSWER---Acute
Maintenance (HTN/bc)
Supplemental (insulin)
Palliative
Supportive (IV fluid)
Prophylactic
Empirical (broad-spectrum abx)
Idiosyncratic Effect - ANSWER---Unexpected response to medication
Tolerance - ANSWER---Declining response to a drug
Dependence - ANSWER---Physiological/psychological need for a drug; needs
drug for normal function
Addiction - ANSWER---Compulsive use of a drug despite negative/dangerous
effects
Drug interactions: drug-drug - ANSWER---When 2 drugs compete for
metabolizing enzymes
Drug interactions: food-drug - ANSWER---Grapefruit juice or leafy greens
, Nr 565 / Nr565 advanced pharmacology fundamentals
week 1 Quiz With Questions And Correct Detailed
Answers 2024-2025 Updated
Drug interactions: additive - ANSWER---1+1 = 2; both provide intended effect
Drug interactions: antagonistic - ANSWER---1+1 = <2; less than desired effect of
one or both drugs
Drug interactions: synergistic - ANSWER---1+1 = >2; sum total effect is greater
than if given alone (i.e. lisinopril + HCTZ)
Drug interactions: incompatibility - ANSWER---1+1 does not equal 2; two IV
drugs given together causing decomposition of one or both drugs
8 rights of medication administration - ANSWER---Patient
Medication
Dose
Route
Time
Reason
Response
Documentation
Adverse reactions: pharmacologic - ANSWER---Extension of a drug's normal
effect