AANPCB-FNP Exam Revision Question
and Answers.
Hegar's sign -
\Softening of lower uterine segment
Chadwick's sign -
\Bluish color of cervix and vagina at 6-8 weeks
Goodell's sign -
\Softening of cervix at 4+ weeks
Lipids in chronic inactivity -
\Low HDL
Lipids in under- or untreated hypothyroidism -
\Elevated total cholesterol, TG, and LDL
Lipids in chronic renal insufficiency -
\Elevated total cholesterol and TG
Lipids in alcohol abuse -
\Elevated TG, HDL, and LDL
Vaccines with live attenuated viruses -
\MMR, varicella, flu-mist(intranasal), Zostavax
Drugs of choice for abdominal infection -
\Beta lactams + metronidazole (most common); fluoroquinolones
Drugs of choice for urinary tract infection -
\Fluoroquinolones (except moxi), TMP-SMX, fluconazole, b-lactams, nitrofurantoin,
fosfomycin if pt has many allergies
Drugs of choice for pulmonary infections -
\Macrolides, resp fluoroquinolones, b-lactams, doxycycline (MRSA, atypical coverage)
Drugs of choice for skin and soft tissue infections -
\MRSA: TMP-SMZ, doxycycline, clindamycin; b-lactams
Drugs of choice for MRSA -
\Vancomycin, daptomycin , linezolid, TMP-SMZ, doxycycline, ceftaroline
Macrolide drugs -
, \Erythromycin, clarithromycin, azithromycin
Macrolide AEs -
\GI, QT prolongation
Tetracycline uses -
\MRSA, rocky mtn spotted fever, atypicals (mycoplasma pneumonia, chlamydia),
spirochetes (Lyme), h.pylori
Tetracycline AEs -
\GI, teeth, hepatic dysfunction, photosensitivity
Fluoroquinolone drugs -
\Ciprofloxacin, levofloxacin, moxifloxacin
Fluoroquinolone uses -
\UTI (cipro or levo), atypicals (mycoplasma, legionella)
Fluoroquinolones and dairy or vitamins -
\Take 2 hrs before or 4 hours after (decrease concentrations)
Metronidazole (Flagyl) uses -
\C. Diff, vaginitis
Metronidazole AEs -
\GI, peripheral neuropathy, disulfiram reaction
Nitrofurantoin uses -
\UTI -not pyelonephritis due to no systemic absorption
Nitrofurantoin AEs, contraindications -
\Pulmonary fibrosis, contraindicated in CrCl <60 (excludes many elderly)
Aminoglycoside drugs -
\Gentamycin, tobramycin
Aminoglycoside uses -
\Atypical coverage, resistant infections, tobramycin for CF only
Aminoglycoside AEs -
\Ototoxicity (irreversible), nephrotoxicity (reversible)
Aminoglycoside monitoring -
\Renal dose adjust, hearing test, drug level monitoring
Antifungals (azoles) -
and Answers.
Hegar's sign -
\Softening of lower uterine segment
Chadwick's sign -
\Bluish color of cervix and vagina at 6-8 weeks
Goodell's sign -
\Softening of cervix at 4+ weeks
Lipids in chronic inactivity -
\Low HDL
Lipids in under- or untreated hypothyroidism -
\Elevated total cholesterol, TG, and LDL
Lipids in chronic renal insufficiency -
\Elevated total cholesterol and TG
Lipids in alcohol abuse -
\Elevated TG, HDL, and LDL
Vaccines with live attenuated viruses -
\MMR, varicella, flu-mist(intranasal), Zostavax
Drugs of choice for abdominal infection -
\Beta lactams + metronidazole (most common); fluoroquinolones
Drugs of choice for urinary tract infection -
\Fluoroquinolones (except moxi), TMP-SMX, fluconazole, b-lactams, nitrofurantoin,
fosfomycin if pt has many allergies
Drugs of choice for pulmonary infections -
\Macrolides, resp fluoroquinolones, b-lactams, doxycycline (MRSA, atypical coverage)
Drugs of choice for skin and soft tissue infections -
\MRSA: TMP-SMZ, doxycycline, clindamycin; b-lactams
Drugs of choice for MRSA -
\Vancomycin, daptomycin , linezolid, TMP-SMZ, doxycycline, ceftaroline
Macrolide drugs -
, \Erythromycin, clarithromycin, azithromycin
Macrolide AEs -
\GI, QT prolongation
Tetracycline uses -
\MRSA, rocky mtn spotted fever, atypicals (mycoplasma pneumonia, chlamydia),
spirochetes (Lyme), h.pylori
Tetracycline AEs -
\GI, teeth, hepatic dysfunction, photosensitivity
Fluoroquinolone drugs -
\Ciprofloxacin, levofloxacin, moxifloxacin
Fluoroquinolone uses -
\UTI (cipro or levo), atypicals (mycoplasma, legionella)
Fluoroquinolones and dairy or vitamins -
\Take 2 hrs before or 4 hours after (decrease concentrations)
Metronidazole (Flagyl) uses -
\C. Diff, vaginitis
Metronidazole AEs -
\GI, peripheral neuropathy, disulfiram reaction
Nitrofurantoin uses -
\UTI -not pyelonephritis due to no systemic absorption
Nitrofurantoin AEs, contraindications -
\Pulmonary fibrosis, contraindicated in CrCl <60 (excludes many elderly)
Aminoglycoside drugs -
\Gentamycin, tobramycin
Aminoglycoside uses -
\Atypical coverage, resistant infections, tobramycin for CF only
Aminoglycoside AEs -
\Ototoxicity (irreversible), nephrotoxicity (reversible)
Aminoglycoside monitoring -
\Renal dose adjust, hearing test, drug level monitoring
Antifungals (azoles) -
