NKU Pharmacology Midterm MSN 611exam 2024

NKU Pharmacology Midterm MSN 611 exam 2024 5-7 days after the first dose - ✔✔ANSWER✔✔Interval for therapeutic effect of initial warfarin therapy Ace inhibitors ARBs Potassium sparing diuretics Renin inhibitors - ✔✔ANSWER✔✔Know renin -angiotensin -aldosterone inhibitors Adequate IV hydration, allopurinol if hyperuricemia is anticipated. - ✔✔ANSWER✔✔Tumor lysis syndrome management in leukemia patients Anagrelide and Oprelvekin - ✔✔ANSWER✔✔FDA-approved drug use in thrombocytopenia As a neurotransmitter in the brain - ✔✔ANSWER✔✔Histamine that is not found within mast cells functions Ascariasis: Round worm; Albendazole or pyrantel pamoate Symptoms: abd pain, abd obstruction, vomiting, appendicitis if in lungs: PNE, fever, cough, eosinophilia, pulm infiltrates Trichuriasis: Whipworm; Albendaxol or Ivermectin Symptoms: GI symptoms, malnourishment, rectal prolapse - ✔✔ANSWER✔✔Differentiate symptoms of ascariasis and trichuriasis. Behavioral changes, GI symptoms, gingival hyperplasia, osteomalacia, megaloblastic anemia, hirsutism Steven -Johnson syndrome, toxic epidermal necrolysis, systemic lupus erythematosus, neutropenia, leukopenia, hepatic necrosis - ✔✔ANSWER✔✔Adverse effects of chronic phenytoin Block destruction of levodopa > maximizing availability and benefits of dopamine precursor - ✔✔ANSWER✔✔Mechanism of action and side -effect profile of catechol -O-methyltransferase inhibitors. Brain stem - ✔✔ANSWER✔✔The "triptans" exert their serotonin 1B and serotonin 1D agonist effects in the: Calcium -channel blockers and thiazide -type diuretics - ✔✔ANSWER✔✔Type of hypertensive medication should preferentially be considered for African Americans Convulsions, postural hypotension, cardiac arrhythmias - ✔✔ANSWER✔✔Toxic effect of first -generation antihistamines Derived from human sources - ✔✔ANSWER✔✔Derivation of antihemorrhagic agents Directly activate the release of NE while also indirectly causing a release of NE. (ephedrine) - ✔✔ANSWER✔✔Mechanism of action of "mixed acting" sympathomimetic drugs drug regimen typically 3.6 months. Active TB Initial treatment phase: 2 months daily - isonizid, rifampin, pyrazinaminde, ethambutol. Continuation phase: 4 or 7 months Isonizid with rifampin. Total of 6 or 9 months Latent TB infection (LTBI) Isoniazid: daily or twice weekly for 6 -9 months. Rifampin: daily for 4 months Isonizid + rifampentine: weekly for 3 months Multidrug -resistant TB (MDR -TB) Susceptible fluoroquinolone and injectable second -line agent (capreomycin or amikacin) Regimens of at least five drugs recommended Extensively drug -resistant TB (XDR -TB) MDR -TB + additional resistance to fluoroquinolone and at least one of the second -line agents. Treatment individualized - ✔✔ANSWER✔✔Know multiple drug combination treatment for tuberculosis Endothelium - promote vasodilation - ✔✔ANSWER✔✔Nitrates cause nitric oxide to be released from where Epinephrine is mainstay medication. Antihistamines will not be able to treat it alone