Dr.A.Velayutharaj BSc MBBS MD , Asso.Professor , Clinical Biochemistry ,TSRM MCH&RC
Name of Chemistry Absorption, Transport Metabolic functions Good sources Deficiency Ex
the Vitamin excretion manifestations
B-carotene-provitamin From Intestine –to liver by 11 cis retinal –for rhodopsin Cod liver oil Carrots Night blindness Hepato
chylomicrons cycle spinach mangoes Xerophthalmia tenderne
coenzymes Retinol & retinoic acid papaya Bitots spots bones ,
Retinol, Retinal, Blood Retinol binding protein regulate protein synthesis, cell Keratomalacia hair
Vitamin A Retinoic acid in pre albumin growth, differentiation prevent Dryness of skin
Carries retinol keratin synthesis
-carotene an antioxidant
7 dehydro cholesterol Intestine – lymphatics Increases the Intestinal Fish Rickets in children Most to
on UV exposure Alpha 2 globulin absorption of calcium fortified milk osteomalacia in adults deminer
25 hydroxylation in In blood Mineralization and of bones
liver and Stored in liver demineralization of bones renal st
1 hydroxylation in reabsorption of Calcium in
Vitamin D kidney renal tubules
Active form
1,25-DHCC
α Tocopherol is the Intestine –lymph VLDL and Antioxidant and antisterility Sunflower oil Sterility Least to
most active form LDL vitamin
carry in blood protects RBC from hemolysis anemia
Vitamin E stored in adipose tissue, liver, by oxidants
muscle
Phylloquinone (k1)- Intestinal bacteria produce. Post translational modification Cabbage cauliflower Rare Hemoly
plants Menaquinone- bile salts required for of clotting factors such as II, liver clotting time is anaemia
(k2) intestinal bacteria absorption VII, IX, X (formation, v- increased jaundice
Vitamin K Menadione (k3) - chylomicron transport to other carboxy glutamate) Dicumarol & warfarin
synthetic tissues via LDL stored in liver inhibit vit K action
Name of Chemistry Absorption, Transport Metabolic functions Good sources Deficiency Ex
the Vitamin excretion manifestations
B-carotene-provitamin From Intestine –to liver by 11 cis retinal –for rhodopsin Cod liver oil Carrots Night blindness Hepato
chylomicrons cycle spinach mangoes Xerophthalmia tenderne
coenzymes Retinol & retinoic acid papaya Bitots spots bones ,
Retinol, Retinal, Blood Retinol binding protein regulate protein synthesis, cell Keratomalacia hair
Vitamin A Retinoic acid in pre albumin growth, differentiation prevent Dryness of skin
Carries retinol keratin synthesis
-carotene an antioxidant
7 dehydro cholesterol Intestine – lymphatics Increases the Intestinal Fish Rickets in children Most to
on UV exposure Alpha 2 globulin absorption of calcium fortified milk osteomalacia in adults deminer
25 hydroxylation in In blood Mineralization and of bones
liver and Stored in liver demineralization of bones renal st
1 hydroxylation in reabsorption of Calcium in
Vitamin D kidney renal tubules
Active form
1,25-DHCC
α Tocopherol is the Intestine –lymph VLDL and Antioxidant and antisterility Sunflower oil Sterility Least to
most active form LDL vitamin
carry in blood protects RBC from hemolysis anemia
Vitamin E stored in adipose tissue, liver, by oxidants
muscle
Phylloquinone (k1)- Intestinal bacteria produce. Post translational modification Cabbage cauliflower Rare Hemoly
plants Menaquinone- bile salts required for of clotting factors such as II, liver clotting time is anaemia
(k2) intestinal bacteria absorption VII, IX, X (formation, v- increased jaundice
Vitamin K Menadione (k3) - chylomicron transport to other carboxy glutamate) Dicumarol & warfarin
synthetic tissues via LDL stored in liver inhibit vit K action
