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NR508- Advanced Pharmacology - Week 5, TD
Maria is a 46-year-old woman who presents for her yearly physical examination. Her medical
history is notable for borderline hypertension and moderate obesity. Six months ago her fasting
lipid profile was normal. Maria report that her mother and brother have diabetes and
hypertension. She reports that she knows she should be on a low calorie, low fat diet and
exercising but with her full time job and four children, she finds it difficult to exercise, and she
eats out most of the time. She is 66" tall and weighs 219lbs today, no current medication. She
does report taking a multivitamin, biotin Vit-C when she remembers. She is a nonsmoker, only
drinks sweet tea with each meal, 3-4 cups of coffee per day.
Today: BP 155/95mm Hg, TC 234 mg/dL (H - < 200), LDL 137 mg/dL (H- < 130), HDL 35
mg/dL,(L-55) triglycerides 241mg/dL (H- 35 -135), fasting plasma glucose is 179 mg/dL (H- 70
– 100); HgbA1C is 7.4mg/dL (H- < 5.9). Physical Exam reveals notable for acanthosis nigricans
at the neck but otherwise is normal.
• What are your treatment goals for Maria?
• What is your plan for drug therapy? What is the mechanism of action for each drug?
• Please give five teaching points for each drug prescribed.
• How would you change the plan if her initial HbgA1C was 10.2mg/dL and her fasting
blood glucose was 305mg/dL? Provide a detailed alternative plan with the rationale.
Hello Dr. McMahon and Class,
What are your treatment goals for Maria?
Maria presents to the clinic for her yearly physical examination. Noting that her history is
positive for borderline hypertension and moderate obesity with fasting lipid profile being normal
https://www.coursehero.com/file/31868635/NR508-Week-5J-
TDdocx/
, 2
NR508- Advanced Pharmacology - Week 5, TD
Maria is a 46-year-old woman who presents for her yearly physical examination. Her medical
history is notable for borderline hypertension and moderate obesity. Six months ago her fasting
lipid profile was normal. Maria report that her mother and brother have diabetes and
hypertension. She reports that she knows she should be on a low calorie, low fat diet and
exercising but with her full time job and four children, she finds it difficult to exercise, and she
eats out most of the time. She is 66" tall and weighs 219lbs today, no current medication. She
does report taking a multivitamin, biotin Vit-C when she remembers. She is a nonsmoker, only
drinks sweet tea with each meal, 3-4 cups of coffee per day.
Today: BP 155/95mm Hg, TC 234 mg/dL (H - < 200), LDL 137 mg/dL (H- < 130), HDL 35
mg/dL,(L-55) triglycerides 241mg/dL (H- 35 -135), fasting plasma glucose is 179 mg/dL (H- 70
– 100); HgbA1C is 7.4mg/dL (H- < 5.9). Physical Exam reveals notable for acanthosis nigricans
at the neck but otherwise is normal.
• What are your treatment goals for Maria?
• What is your plan for drug therapy? What is the mechanism of action for each drug?
• Please give five teaching points for each drug prescribed.
• How would you change the plan if her initial HbgA1C was 10.2mg/dL and her fasting
blood glucose was 305mg/dL? Provide a detailed alternative plan with the rationale.
Hello Dr. McMahon and Class,
What are your treatment goals for Maria?
Maria presents to the clinic for her yearly physical examination. Noting that her history is
positive for borderline hypertension and moderate obesity with fasting lipid profile being normal
https://www.coursehero.com/file/31868635/NR508-Week-5J-
TDdocx/
