BIS 010 Final Exam Review|Qustions and
Answers
1. From the DNA sequence 5' TACCGG 3', what is expected to be its comple- mentary DNA
sequence?: 5' ATGGCC 3'
2. An accidental mutation in a gene generated a nonsense mutation in the middle of the gene.
What happens?: Translation will stop at the mutation site.
3. Using the genetic code provided below, which polypeptide could be made from the following piece
of an mRNA: 5'-...CAUGUUGAGCAAA...-3' ? (first three amino acids are indicated in the followings):
Met-Leu-Ser, because AUG is universal start
4. Brain cells and skin cells in my body have same DNA genomes. But they turn on/off different
sets of genes for their different functions. (T/F): true
5. Which of the following statements is TRUE about DNA replication?: base pairing is critical for
DNA replication.
6. The enzyme that carries out transcription is: DNA dependent RNA poly- merase
7. Which of the following is INCORRECT about a difference and a similarity between plants and
animals?: The DNA sequence in plants and animals are identical. But they turn on different
sets of genes.
8. The drug Remdesivir was originally developed to treat Ebola virus. It is now being used to treat
some COVID-19 patients. While it is not a cure, it does appear to help some patients. Why might this
drug have some activity against COVID-19, even though it was developed to treat a different virus?:
The drug might target the RNA-dependent RNA polymerase enzyme which is found in the
genome of both viruses
9. During transcription, what happens when RNA polymerase encounters A nucleotide in the
DNA?: U is added to the RNA
10.Which of the following is NOT a potential consequence of a point muta- tion?: generation of a
frameshift mutation
11.Which of the following statement is INCORRECT about mutations?: Muta- tions can occur
during protein translation.
12.In 2020, two women scientists (Drs. Emmanuelle Charpentier and Jennifer Doudna) received the
shared Nobel Prize in Chemistry for their discovery of CRISPR/Cas9 system. Which of the following is
a CORRECT description for
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, BIS 010 Final Exam Review|Qustions and
Answers
their discovery?: We can use CRISPR/Cas9 to mutate any gene-of-interest for treating patients
such as HIV patients
13.When I analyzed the composition of DNA in a wild bear, I found that A nu- cleotide comprises
about 30%. Which of the following statements is CORRECT
?: there should be an equal amount of T, 30%.
14.Translation occurs in the cytoplasm: true
15.Which type of mutation would have no effect on the protein encoded by a gene?: Silent
mutation
16.The Moderna and Pfizer vaccines against COVID-19 approved for use in United States contain
mRNA molecules. These mRNA molecules encode the information for:: a piece of viral protein
17.Which of the following is a CORRECT description on antiviral therapeutic strategies?: To avoid
the emergence of resistant viruses, a strategy to combine multiple antiviral drugs would be
ideal.
18.Gene regulation means how cells copy DNA molecules.: false
19.translation ends at the: stop codon
20.All proteins begin with an amino acid, methionine.: true
21.The reason why different viruses infect different cell types is because different viruses
utilize different receptors of host cells: true
22.Use the following figure to help answer this question. Which o ing statements is a f the
CORRECT explanation for this figure?: Hydr between the nitrogen-containing bases follow- ogen
are critical for the double-stra structure bonds nded
23.Which of the following statements about the central dogma is FALSE:: -
Replication is carried out by the RNA Polymerase enzyme.
24.Which of the following is a relevant interaction for the base paring that allows DNA to be
copied accurately during replication?: Hydrogen bonds
25.Which of the following is CORRECT about the description about valence electrons of atoms?:
One carbon atom has four valence electrons
26.Which of the following is a testable statement?: Red birthday candles burn longer than green
birthday candles.
27.Which of the following is INCORRECT for a property of water?: Water's hydrogen and
oxygen atoms are connected with hydrogen bonds
28.Evolutionary relationships among species are deduced from shared char- acteristics, including
DNA.: true
29.Which of the following is CORRECT?: Human and other primates share a common
ancestor
30.Dr. Blehert took healthy bats into his laboratory. He exposed some of them to fungus suspected
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Answers
1. From the DNA sequence 5' TACCGG 3', what is expected to be its comple- mentary DNA
sequence?: 5' ATGGCC 3'
2. An accidental mutation in a gene generated a nonsense mutation in the middle of the gene.
What happens?: Translation will stop at the mutation site.
3. Using the genetic code provided below, which polypeptide could be made from the following piece
of an mRNA: 5'-...CAUGUUGAGCAAA...-3' ? (first three amino acids are indicated in the followings):
Met-Leu-Ser, because AUG is universal start
4. Brain cells and skin cells in my body have same DNA genomes. But they turn on/off different
sets of genes for their different functions. (T/F): true
5. Which of the following statements is TRUE about DNA replication?: base pairing is critical for
DNA replication.
6. The enzyme that carries out transcription is: DNA dependent RNA poly- merase
7. Which of the following is INCORRECT about a difference and a similarity between plants and
animals?: The DNA sequence in plants and animals are identical. But they turn on different
sets of genes.
8. The drug Remdesivir was originally developed to treat Ebola virus. It is now being used to treat
some COVID-19 patients. While it is not a cure, it does appear to help some patients. Why might this
drug have some activity against COVID-19, even though it was developed to treat a different virus?:
The drug might target the RNA-dependent RNA polymerase enzyme which is found in the
genome of both viruses
9. During transcription, what happens when RNA polymerase encounters A nucleotide in the
DNA?: U is added to the RNA
10.Which of the following is NOT a potential consequence of a point muta- tion?: generation of a
frameshift mutation
11.Which of the following statement is INCORRECT about mutations?: Muta- tions can occur
during protein translation.
12.In 2020, two women scientists (Drs. Emmanuelle Charpentier and Jennifer Doudna) received the
shared Nobel Prize in Chemistry for their discovery of CRISPR/Cas9 system. Which of the following is
a CORRECT description for
Contact for help with assignments .
, BIS 010 Final Exam Review|Qustions and
Answers
their discovery?: We can use CRISPR/Cas9 to mutate any gene-of-interest for treating patients
such as HIV patients
13.When I analyzed the composition of DNA in a wild bear, I found that A nu- cleotide comprises
about 30%. Which of the following statements is CORRECT
?: there should be an equal amount of T, 30%.
14.Translation occurs in the cytoplasm: true
15.Which type of mutation would have no effect on the protein encoded by a gene?: Silent
mutation
16.The Moderna and Pfizer vaccines against COVID-19 approved for use in United States contain
mRNA molecules. These mRNA molecules encode the information for:: a piece of viral protein
17.Which of the following is a CORRECT description on antiviral therapeutic strategies?: To avoid
the emergence of resistant viruses, a strategy to combine multiple antiviral drugs would be
ideal.
18.Gene regulation means how cells copy DNA molecules.: false
19.translation ends at the: stop codon
20.All proteins begin with an amino acid, methionine.: true
21.The reason why different viruses infect different cell types is because different viruses
utilize different receptors of host cells: true
22.Use the following figure to help answer this question. Which o ing statements is a f the
CORRECT explanation for this figure?: Hydr between the nitrogen-containing bases follow- ogen
are critical for the double-stra structure bonds nded
23.Which of the following statements about the central dogma is FALSE:: -
Replication is carried out by the RNA Polymerase enzyme.
24.Which of the following is a relevant interaction for the base paring that allows DNA to be
copied accurately during replication?: Hydrogen bonds
25.Which of the following is CORRECT about the description about valence electrons of atoms?:
One carbon atom has four valence electrons
26.Which of the following is a testable statement?: Red birthday candles burn longer than green
birthday candles.
27.Which of the following is INCORRECT for a property of water?: Water's hydrogen and
oxygen atoms are connected with hydrogen bonds
28.Evolutionary relationships among species are deduced from shared char- acteristics, including
DNA.: true
29.Which of the following is CORRECT?: Human and other primates share a common
ancestor
30.Dr. Blehert took healthy bats into his laboratory. He exposed some of them to fungus suspected
Contact for help with assignments .
