~
The apex of the renal pyramid contains zo or so
papillary ducts ducts of Bellini & this is
region
called Area Cribrosa
.
Microscopically ; 3 structures
might be observed
~
in the cortex
.
1 Red , dot-like the Renal Corpuscles
granules , .
2
Convoluted tubules ; the Cortical Labyrinth.
3 .
Longitudinal Strictions ; Medulla
rays
.
Other
filtering
~
than excretion ,
a balance , the
Kidney also help to
regulate blood pressure &
hemodynamics .
~
Kidneys also have an endocrine function; they produce
renin &
erythropoietin A medullary forms the axis of the renal lobule
prostaglanding
~
,
.
ray .
~
They also convert a
precursor of vitamin D into
the active vitamin :
Uriniferous Tubules
~
Kidney lie retro ~
The functional unit of the kidney Fluid passes
peritoneally & the is lower than
right
~
,
.
modified before
the left due to the liver .
through itI
gets becoming urine
.
It contains hilum where the renal A & Consists of 2 parts ; the Nephron O
medially
~
a concave
,
.
vein, lymph vessels & the wreter enter & exit
. the
collecting tubule
~
The Kidneys contain a fibrous capsule that ~
Separated from the connective tissue by the
consists of dense,
irregular collagenous connective tissue .
basal Lamina .
Nephrons
-
~
Made up of Renal Corpuscle + Tubular Section -
2 types :
~
Shorter cortical nephrons
is divided into
Kidney outer cortical & inner medulla
Longer juxtamedullary nephrons.
~
an an
Columns called the columns of Bertin separate
region .
the
Medulla into 6-12 pieces
Medulla is also known
·
as
Renal Pyramid
.
, Renal Corpuscle
Extraglomerular mesangial cells
.
1 .
-
Renalis located at vascular pole
Also called the corpusculum
Malpighi
~
~
the
Found in & consists of
Intraglomerular mesangial cells
~ 2
the cortex : .
·
Glomerulus ~
located within the renal corpuscle
.
& contain receptors for vasconstrictors
Glomerular
phagocytic
~
Bowman's capsule
·
visceral & parietal layers .
such as
angiotensin
Vascular pole : &
the where the vessels
supplying draining
~
region
the
glomerulus enter & exit ·
Supply Blood in
through the afferent arteriole
·
comes
Draining leaves the efferent arteriole
·
Blood
through .
The efferent arteriole has to blood
greater resistance
·
a
flow .
Urinary
~
pole : the of continuation between the renal
region
Corpuscle & proximal tubule Basal Lamina
~
Filtrate Z
layers
~
out of the
Leaking glomerulus
~
enter the :
Bowman's space filtration barrierr. Lamina densa : middle dense layer & consists
through
·
a
The barrier is composed of : of type
collagen composed of 23 , 24 , da chains
~
·
Basal Lamina
. Endothelial wall of the capillary. ·
Lamina rarae : 2 less electron dense layers .
Visceral Contains Laminin, fibronectin &
highly
·
Layer of Bowman's capsule.
hydrated polyanionic proteoglycans·
Laminin & fibronectin help the pedicels
& endothelial cells to stay attached to basallamina
.
The 2 layers : Lamina vara interna o
externa on either sides of the Lamina densa
.
Glomerulus
num
·
Perlacan &
agrin both rich in heparan
Several tuft fenestrated capillaries that
of
merged sulfate found both layers
~
are on rarae ·
arise from branches of the afferent Mutations in
glomerular arteriole & zy chain of type IV
collagen result
~
· 23
~
It contains a special type of cells; the
mesangial in Alpert's syndrome
cells There.
are 2
groups mesangial cells .
The apex of the renal pyramid contains zo or so
papillary ducts ducts of Bellini & this is
region
called Area Cribrosa
.
Microscopically ; 3 structures
might be observed
~
in the cortex
.
1 Red , dot-like the Renal Corpuscles
granules , .
2
Convoluted tubules ; the Cortical Labyrinth.
3 .
Longitudinal Strictions ; Medulla
rays
.
Other
filtering
~
than excretion ,
a balance , the
Kidney also help to
regulate blood pressure &
hemodynamics .
~
Kidneys also have an endocrine function; they produce
renin &
erythropoietin A medullary forms the axis of the renal lobule
prostaglanding
~
,
.
ray .
~
They also convert a
precursor of vitamin D into
the active vitamin :
Uriniferous Tubules
~
Kidney lie retro ~
The functional unit of the kidney Fluid passes
peritoneally & the is lower than
right
~
,
.
modified before
the left due to the liver .
through itI
gets becoming urine
.
It contains hilum where the renal A & Consists of 2 parts ; the Nephron O
medially
~
a concave
,
.
vein, lymph vessels & the wreter enter & exit
. the
collecting tubule
~
The Kidneys contain a fibrous capsule that ~
Separated from the connective tissue by the
consists of dense,
irregular collagenous connective tissue .
basal Lamina .
Nephrons
-
~
Made up of Renal Corpuscle + Tubular Section -
2 types :
~
Shorter cortical nephrons
is divided into
Kidney outer cortical & inner medulla
Longer juxtamedullary nephrons.
~
an an
Columns called the columns of Bertin separate
region .
the
Medulla into 6-12 pieces
Medulla is also known
·
as
Renal Pyramid
.
, Renal Corpuscle
Extraglomerular mesangial cells
.
1 .
-
Renalis located at vascular pole
Also called the corpusculum
Malpighi
~
~
the
Found in & consists of
Intraglomerular mesangial cells
~ 2
the cortex : .
·
Glomerulus ~
located within the renal corpuscle
.
& contain receptors for vasconstrictors
Glomerular
phagocytic
~
Bowman's capsule
·
visceral & parietal layers .
such as
angiotensin
Vascular pole : &
the where the vessels
supplying draining
~
region
the
glomerulus enter & exit ·
Supply Blood in
through the afferent arteriole
·
comes
Draining leaves the efferent arteriole
·
Blood
through .
The efferent arteriole has to blood
greater resistance
·
a
flow .
Urinary
~
pole : the of continuation between the renal
region
Corpuscle & proximal tubule Basal Lamina
~
Filtrate Z
layers
~
out of the
Leaking glomerulus
~
enter the :
Bowman's space filtration barrierr. Lamina densa : middle dense layer & consists
through
·
a
The barrier is composed of : of type
collagen composed of 23 , 24 , da chains
~
·
Basal Lamina
. Endothelial wall of the capillary. ·
Lamina rarae : 2 less electron dense layers .
Visceral Contains Laminin, fibronectin &
highly
·
Layer of Bowman's capsule.
hydrated polyanionic proteoglycans·
Laminin & fibronectin help the pedicels
& endothelial cells to stay attached to basallamina
.
The 2 layers : Lamina vara interna o
externa on either sides of the Lamina densa
.
Glomerulus
num
·
Perlacan &
agrin both rich in heparan
Several tuft fenestrated capillaries that
of
merged sulfate found both layers
~
are on rarae ·
arise from branches of the afferent Mutations in
glomerular arteriole & zy chain of type IV
collagen result
~
· 23
~
It contains a special type of cells; the
mesangial in Alpert's syndrome
cells There.
are 2
groups mesangial cells .
