NSG5003 Week 2 Exam Questions
And Answers. Verified And Updated.
Hypersensitivity is best defined as a(an) - answer✔✔c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - answer✔✔Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins? - answer✔✔IgE
Which type of antibody is involved in type I hypersensitivity reaction? - answer✔✔IgE
Blood transfusion reactions are an example of: - answer✔✔Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? - answer✔✔c.
Eosinophils
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a result of
which receptor action? - answer✔✔Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed to
develop allergies? - answer✔✔c.
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions? - answer✔✔d.
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the erythrocytes are
destroyed by - answer✔✔a.
Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood cells are
destroyed by: - answer✔✔Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a result of: -
answer✔✔d.
EXAM STUDY MATERIALS July 25, 2024 1:06 PM
,Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction? - answer✔✔d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity reaction? -
answer✔✔Modulation
Type III hypersensitivity reactions are a result of which of the following? - answer✔✔b.
Antibodies binding to soluble antigens that were released into body fluids and the immune
complexes being deposited in the tissues
A type IV hypersensitivity reaction causes which result? - answer✔✔.
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes that are
deposited in tissues are a result of: - answer✔✔Complement activation
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to: -
answer✔✔a.
Immune complexes that are deposited in capillary beds, blocking circulation
Deficiencies in which element can produce depression of both B- and T-cell function? -
answer✔✔Zinc
When the maternal immune system becomes sensitized against antigens expressed by the fetus,
what reaction occurs? - answer✔✔Alloimmunity
Tissue damage caused by the deposition of circulating immune complexes containing an
antibody against the host DNA is the cause of which disease? - answer✔✔Systemic lupus
erythematosus
Why does tissue damage occurs in acute rejection after organ transplantation? - answer✔✔a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly
attack the endothelial cells of the transplanted tissue.
Which blood cell carries the carbohydrate antigens for blood type? - answer✔✔Erythrocytes
A person with type O blood is likely to have high titers of which anti-antibodies? - answer✔✔A
and B
Which class of immunoglobulins forms isohemagglutinins? - answer✔✔IgM
EXAM STUDY MATERIALS July 25, 2024 1:06 PM
, Which component of the immune system is deficient in individuals with infections caused by
viruses, fungi, or yeast? - answer✔✔T cells
In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity? -
answer✔✔DiGeorge syndrome
How many months does it take for the newborn to be sufficiently protected by antibodies
produced by its own B cells? - answer✔✔6 to 8
Considering the effects of nutritional deficiencies on the immune system, severe deficits in
calories and protein lead to deficiencies in the formation of which immune cells? - answer✔✔T
cells
Urticaria are a manifestation of a which type of hypersensitivity reaction? - answer✔✔Type I
Graves disease is a result of: - answer✔✔c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites
Raynaud phenomenon is an example of which type of hypersensitivity? - answer✔✔Type III
Which statement is true concerning an atopic individual? - answer✔✔They tend to produce more
Fc receptors.
Which statement is true regarding immunodeficiency? - answer✔✔a.
Immunodeficiency is generally not present in other family members
A person with type O blood is considered to be the universal blood donor because type O blood
contains which of the following? - answer✔✔No antigens
Immunoglobulin E (IgE) is associated with which type of hypersensitivity reaction? -
answer✔✔Type I
Graves disease is an autoimmune disease that results in which maternal antibody? - answer✔✔b.
Affecting the receptor for TSH, causing neonatal hyperthyroidism
When a tuberculin skin test is positive, the hard center and erythema surrounding the induration
are a result of which of the following? (Select all that apply.) - answer✔✔T lymphocytes and
Macrophages
Exposure to which of the following could result in a type IV hypersensitivity reaction? (Select all
that apply.) - answer✔✔Poison Ivy, Neomycin, Nickel, Detergents
Which disorders are considered autoimmune? (Select all that apply - answer✔✔Crohns,
Addisons, Rheumatoid arthritis, systemic lupus erythematosus
EXAM STUDY MATERIALS July 25, 2024 1:06 PM
And Answers. Verified And Updated.
Hypersensitivity is best defined as a(an) - answer✔✔c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - answer✔✔Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins? - answer✔✔IgE
Which type of antibody is involved in type I hypersensitivity reaction? - answer✔✔IgE
Blood transfusion reactions are an example of: - answer✔✔Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? - answer✔✔c.
Eosinophils
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a result of
which receptor action? - answer✔✔Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed to
develop allergies? - answer✔✔c.
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions? - answer✔✔d.
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the erythrocytes are
destroyed by - answer✔✔a.
Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood cells are
destroyed by: - answer✔✔Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a result of: -
answer✔✔d.
EXAM STUDY MATERIALS July 25, 2024 1:06 PM
,Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction? - answer✔✔d.
Natural killer cells
Graves disease (hyperthyroidism) is an example of which type II hypersensitivity reaction? -
answer✔✔Modulation
Type III hypersensitivity reactions are a result of which of the following? - answer✔✔b.
Antibodies binding to soluble antigens that were released into body fluids and the immune
complexes being deposited in the tissues
A type IV hypersensitivity reaction causes which result? - answer✔✔.
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes that are
deposited in tissues are a result of: - answer✔✔Complement activation
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to: -
answer✔✔a.
Immune complexes that are deposited in capillary beds, blocking circulation
Deficiencies in which element can produce depression of both B- and T-cell function? -
answer✔✔Zinc
When the maternal immune system becomes sensitized against antigens expressed by the fetus,
what reaction occurs? - answer✔✔Alloimmunity
Tissue damage caused by the deposition of circulating immune complexes containing an
antibody against the host DNA is the cause of which disease? - answer✔✔Systemic lupus
erythematosus
Why does tissue damage occurs in acute rejection after organ transplantation? - answer✔✔a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly
attack the endothelial cells of the transplanted tissue.
Which blood cell carries the carbohydrate antigens for blood type? - answer✔✔Erythrocytes
A person with type O blood is likely to have high titers of which anti-antibodies? - answer✔✔A
and B
Which class of immunoglobulins forms isohemagglutinins? - answer✔✔IgM
EXAM STUDY MATERIALS July 25, 2024 1:06 PM
, Which component of the immune system is deficient in individuals with infections caused by
viruses, fungi, or yeast? - answer✔✔T cells
In which primary immune deficiency is there a partial-to-complete absence of T-cell immunity? -
answer✔✔DiGeorge syndrome
How many months does it take for the newborn to be sufficiently protected by antibodies
produced by its own B cells? - answer✔✔6 to 8
Considering the effects of nutritional deficiencies on the immune system, severe deficits in
calories and protein lead to deficiencies in the formation of which immune cells? - answer✔✔T
cells
Urticaria are a manifestation of a which type of hypersensitivity reaction? - answer✔✔Type I
Graves disease is a result of: - answer✔✔c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites
Raynaud phenomenon is an example of which type of hypersensitivity? - answer✔✔Type III
Which statement is true concerning an atopic individual? - answer✔✔They tend to produce more
Fc receptors.
Which statement is true regarding immunodeficiency? - answer✔✔a.
Immunodeficiency is generally not present in other family members
A person with type O blood is considered to be the universal blood donor because type O blood
contains which of the following? - answer✔✔No antigens
Immunoglobulin E (IgE) is associated with which type of hypersensitivity reaction? -
answer✔✔Type I
Graves disease is an autoimmune disease that results in which maternal antibody? - answer✔✔b.
Affecting the receptor for TSH, causing neonatal hyperthyroidism
When a tuberculin skin test is positive, the hard center and erythema surrounding the induration
are a result of which of the following? (Select all that apply.) - answer✔✔T lymphocytes and
Macrophages
Exposure to which of the following could result in a type IV hypersensitivity reaction? (Select all
that apply.) - answer✔✔Poison Ivy, Neomycin, Nickel, Detergents
Which disorders are considered autoimmune? (Select all that apply - answer✔✔Crohns,
Addisons, Rheumatoid arthritis, systemic lupus erythematosus
EXAM STUDY MATERIALS July 25, 2024 1:06 PM
