2024 NURS 676, ADVANCED PHARMACOLOGY
FINAL EXAM (SPRING QTR) WITH 100%
CORRECT ANSWERS WITH RATIONALE AND
GRADED A+ (SUCCESS GUARANTEE):WEST
COAST UNIVERSITY
What is extremely resistant TB resistant to?
a. ) One of the second line injectable second line drugs and all fluoroquinolones
b. ) All Fluoroquinolones ; Isoniazid [INH] and rifampin; and at least one of the
injectable second line drugs.
c.) One of the second line injectable second line drugs and rifampin and INH
d.) INH and rifampin, and all fluroroquinolones - ANSWER b. ) All Fluoroquinolones
; Isoniazid [INH] and rifampin; and at least one of the injectable second line drugs.
What is multidrug resistant TB?
a.) Resistant to both Isoniazid (INH) and fluoroquinolones
b.) Resistant to both rifampin and fluoroquinolones
c. ) Resistant to Pyrazinamide and ethambutol
d.) Resistant to both Isoniazid (INH) and Rifampin - ANSWER d.) Resistant to both
Isoniazid (INH) and Rifampin
Which medications create problematic interactions with other HIV antiviral drugs?
a.) Rifampin and Rifabutin
b.) Rifampin and Amantadine
c.) Rifampin and Isoniazid [INH]
d.) Rifampin and Pyrazinamide (PZA) - ANSWER a.) Rifampin and Rifabutin
Treating one infection interferes with treatment of the other in patients with both TB
and HIV.
a.) True
b.) False - ANSWER a.) True
John has HIV and has just been diagnosed with TB. What is the minimum amount of
time he will need therapy?
a.) 3 months
b.) 6 months
c.) 9 months
d.) 1 year - ANSWER b.) 6 months
Which information should the nurse include when teaching a patient about INH
therapy?
a.) Tubercle bacilli cannot develop resistance to isoniazid during treatment.
b.) Isoniazid is administered intravenously.
,c.) An adverse effect of isoniazid therapy is peripheral neuropathy, which can be
reversed with pyridoxine.
d.) The dose of INH should be lowered if the patient is also taking phenytoin -
ANSWER c.) An adverse effect of isoniazid therapy is peripheral neuropathy, which
can be reversed with pyridoxine.
A group of college students are traveling to a chloroquine-resistant malaria area for a
mission trip. Which of the following medications can be used for both prevention and
treatment of malaria in these students?
Malaria not covered in text. Will need to look this up.
a.) Pyrimethamine
b.) Artemisinin
c.) Atoraquone-proguanil
d.) Melarsoprol - ANSWER c.) Atoraquone-proguanil
Which information should be included when teaching about rifampin?
a.) Rifampin is safe to use in patients who have hepatic disease
b.) Rifampin can change the color of body fluids to reddish orange
c.) Rifampin cannot be given IV
d.) Oral contraceptives are safe to use with rifampin therapy - ANSWER b.)
Rifampin can change the color of body fluids to reddish orange
Which TB medication can cause decrease in vision?
a.) Ethambutol
b.) Rifampin
c.) Isoniazid (INH)
d.) Pyrazinamide - ANSWER a.) Ethambutol
Linda has onychomychosis of the toenail. Which of the following is the appropriate
treatment?
a.) Ketoconazole daily for 6 months
b.) Ketoconazole daily for 3months
c.) Terbinafine daily for 6 months
d.) Terbinafine daily for 3 months - ANSWER d.) Terbinafine daily for 3 months
Lisa is taking terbinafine daily for toenail fungus. Which of the following labs does the
NP need to monitor?
a.) Liver enzymes baseline and monthly
b.) Basic metabolic panel in 3 months
c.) BUN/Cr monthly
d.) CBC once only - ANSWER a.) Liver enzymes baseline and monthly
Jonathan has athlete's foot. Which of the following should be prescribed initially?
a.) Terbinafine topical
b.) Ketoconazole topical
c.) Griseofulvin orally
d.) Terbinafine orally - ANSWER a.) Terbinafine topical
Jade comes in with vaginal Candidiasis. What is the NP going to prescribe?
a.) Metronidazole 150 mg by mouth for 7 days
,b.) Metronidazole 150 mg by mouth once
c.) Fluconazole 150 mg by month once
d.) Fluconazole 150 mg by mouth daily for 5 days - ANSWER c.) Fluconazole 150
mg by month once
Sally comes in for the treatment of tinea capitis? What is the NP going to prescribe?
a.) Grisofulvin by mouth daily
b. )Terbinafine cream
c.) Ketoconazole by mouth daily
d.) Econazole cream - ANSWER a.) Grisofulvin by mouth daily
Brittany is a 23 year old female and culture is positive for bacterial vaginosis. Which
of the following would be the appropriate treatment?
a.) Clotrimazole 1% cream intravaginally daily for 7-14 days
b.) Metronidazole gel 0.75% , one full applicator intravaginally once daily for 5 days
c.) Fluconazole 150 mg by mouth once
d.) Metronidazole 1000 mg twice daily by mouth for 7 days - ANSWER b.)
Metronidazole gel 0.75% , one full applicator intravaginally once daily for 5 days
Randy is a 19 year old male and has been diagnosed with chlamydia. Which of the
following is the appropriate treatment?
a.) Nitrofurantoin 100 mg by mouth twice daily for 7 days
b.) Doxycycline 100 mg po twice daily for 7 days
c.) Amoxicillin 250 mg by mouth daily for 5 days
d.) Azithromycin 2 g by mouth in a single dose - ANSWER b.) Doxycycline 100 mg
po twice daily for 7 days
Madeline is a 29 year old with genital herpes and would like suppressive therapy.
Which of the following is the appropriate treatment?
a.) Valacyclovir 500 mg by mouth daily for 1 year
b.) Acyclovir 200 mg daily for 6 months
c.) Famciclovir 250mg daily for 6 months
d.) There are no medications for suppressive therapy - ANSWER a.) Valacyclovir
500 mg by mouth daily for 1 year
Treatment for an 18 year old non pregnant female with uncomplicated cervix
infection with gonorrhea and chlamydial infection has not been excluded is:
a.) Ceftriaxone 500 mg IM once
b.) Ceftriaxone 500 mg IM plus Doxycycline 100 mg po twice daily for 7 days
c.) Ceftriaxone 250 mg IM plus Azithromycin 1 gm PO orally
d.) Azithromycin 1 gram by mouth once - ANSWER b.) Ceftriaxone 500 mg IM plus
Doxycycline 100 mg po twice daily for 7 days
Jake a 34 year old male has primary syphilis. What is appropriate treatment?
a.) Doxycycline 100 mg by mouth daily for 7 days
b.) Azithromycin 1 gram by mouth once
c.) Bicillin C-R IM
d.) Benzathine penicillin G (Bicillin LA) IM - ANSWER d.) Benzathine penicillin G
(Bicillin LA) IM
, Lauren a 22 year old female comes into the clinic and is diagnosed with
Trichomoniasis. The NP can prescribe: Check all that apply.
a. ) Metronidazole 500 by mouth twice daily for 7 days
b.) Metronidazole 3 gram by mouth in a single dose
c.) Metronidazole gel 0.75% one full applicator invravaginally once daily for 5 days
d.) Tinidazole 2 gram by mouth in a single dose
e.) Metronidazole 2 gram by mouth in a single dose - ANSWER a. ) Metronidazole
500 by mouth twice daily for 7 days
d.) Tinidazole 2 gram by mouth in a single dose
What do you tell the patient taking metronidazole about drinking alcohol? Check all
that apply.
a.) One glass of wine daily is ok while taking metronidazole
b.) Metronidazole can cause a disulferam-like reaction if taken with alcohol
c.) Alcohol must be avoided completely during treatment and for 72 hours after
treatment
d.) Alcohol can be consumed in moderate amounts - ANSWER b.) Metronidazole
can cause a disulferam-like reaction if taken with alcohol
c.) Alcohol must be avoided completely during treatment and for 72 hours after
treatment
Max is a 70 year old diabetic with shingles. What lab test would you want to order
prior to starting an antivral?
a.) CBC
b.) BUN/Cr
c.) ALT
d.) AST - ANSWER b.) BUN/Cr
Which of the following medications is used for herpes labialis?
a.) Benzocaine gel
b.)Valganciclovir
c.) Penciclovir
d.) Ganciclovir - ANSWER c.) Penciclovir
Which of the following can be given if started within 48 hours of onset of flu
symptoms. Check all that apply.
a. ) Oseltamavir
b.) Zanamivir
c.) Ribavirin
d.) Telbivudine - ANSWER a. ) Oseltamavir
b.) Zanamivir
Which of the following antivirals does the CDC no longer recommend for flu due to
resistance?
a. ) Zanamivir
b.) Amantadine
c.) Oseltamivir
d.) peramivir - ANSWER b.) Amantadine
What is the first drug given for HIV prophylaxis?
FINAL EXAM (SPRING QTR) WITH 100%
CORRECT ANSWERS WITH RATIONALE AND
GRADED A+ (SUCCESS GUARANTEE):WEST
COAST UNIVERSITY
What is extremely resistant TB resistant to?
a. ) One of the second line injectable second line drugs and all fluoroquinolones
b. ) All Fluoroquinolones ; Isoniazid [INH] and rifampin; and at least one of the
injectable second line drugs.
c.) One of the second line injectable second line drugs and rifampin and INH
d.) INH and rifampin, and all fluroroquinolones - ANSWER b. ) All Fluoroquinolones
; Isoniazid [INH] and rifampin; and at least one of the injectable second line drugs.
What is multidrug resistant TB?
a.) Resistant to both Isoniazid (INH) and fluoroquinolones
b.) Resistant to both rifampin and fluoroquinolones
c. ) Resistant to Pyrazinamide and ethambutol
d.) Resistant to both Isoniazid (INH) and Rifampin - ANSWER d.) Resistant to both
Isoniazid (INH) and Rifampin
Which medications create problematic interactions with other HIV antiviral drugs?
a.) Rifampin and Rifabutin
b.) Rifampin and Amantadine
c.) Rifampin and Isoniazid [INH]
d.) Rifampin and Pyrazinamide (PZA) - ANSWER a.) Rifampin and Rifabutin
Treating one infection interferes with treatment of the other in patients with both TB
and HIV.
a.) True
b.) False - ANSWER a.) True
John has HIV and has just been diagnosed with TB. What is the minimum amount of
time he will need therapy?
a.) 3 months
b.) 6 months
c.) 9 months
d.) 1 year - ANSWER b.) 6 months
Which information should the nurse include when teaching a patient about INH
therapy?
a.) Tubercle bacilli cannot develop resistance to isoniazid during treatment.
b.) Isoniazid is administered intravenously.
,c.) An adverse effect of isoniazid therapy is peripheral neuropathy, which can be
reversed with pyridoxine.
d.) The dose of INH should be lowered if the patient is also taking phenytoin -
ANSWER c.) An adverse effect of isoniazid therapy is peripheral neuropathy, which
can be reversed with pyridoxine.
A group of college students are traveling to a chloroquine-resistant malaria area for a
mission trip. Which of the following medications can be used for both prevention and
treatment of malaria in these students?
Malaria not covered in text. Will need to look this up.
a.) Pyrimethamine
b.) Artemisinin
c.) Atoraquone-proguanil
d.) Melarsoprol - ANSWER c.) Atoraquone-proguanil
Which information should be included when teaching about rifampin?
a.) Rifampin is safe to use in patients who have hepatic disease
b.) Rifampin can change the color of body fluids to reddish orange
c.) Rifampin cannot be given IV
d.) Oral contraceptives are safe to use with rifampin therapy - ANSWER b.)
Rifampin can change the color of body fluids to reddish orange
Which TB medication can cause decrease in vision?
a.) Ethambutol
b.) Rifampin
c.) Isoniazid (INH)
d.) Pyrazinamide - ANSWER a.) Ethambutol
Linda has onychomychosis of the toenail. Which of the following is the appropriate
treatment?
a.) Ketoconazole daily for 6 months
b.) Ketoconazole daily for 3months
c.) Terbinafine daily for 6 months
d.) Terbinafine daily for 3 months - ANSWER d.) Terbinafine daily for 3 months
Lisa is taking terbinafine daily for toenail fungus. Which of the following labs does the
NP need to monitor?
a.) Liver enzymes baseline and monthly
b.) Basic metabolic panel in 3 months
c.) BUN/Cr monthly
d.) CBC once only - ANSWER a.) Liver enzymes baseline and monthly
Jonathan has athlete's foot. Which of the following should be prescribed initially?
a.) Terbinafine topical
b.) Ketoconazole topical
c.) Griseofulvin orally
d.) Terbinafine orally - ANSWER a.) Terbinafine topical
Jade comes in with vaginal Candidiasis. What is the NP going to prescribe?
a.) Metronidazole 150 mg by mouth for 7 days
,b.) Metronidazole 150 mg by mouth once
c.) Fluconazole 150 mg by month once
d.) Fluconazole 150 mg by mouth daily for 5 days - ANSWER c.) Fluconazole 150
mg by month once
Sally comes in for the treatment of tinea capitis? What is the NP going to prescribe?
a.) Grisofulvin by mouth daily
b. )Terbinafine cream
c.) Ketoconazole by mouth daily
d.) Econazole cream - ANSWER a.) Grisofulvin by mouth daily
Brittany is a 23 year old female and culture is positive for bacterial vaginosis. Which
of the following would be the appropriate treatment?
a.) Clotrimazole 1% cream intravaginally daily for 7-14 days
b.) Metronidazole gel 0.75% , one full applicator intravaginally once daily for 5 days
c.) Fluconazole 150 mg by mouth once
d.) Metronidazole 1000 mg twice daily by mouth for 7 days - ANSWER b.)
Metronidazole gel 0.75% , one full applicator intravaginally once daily for 5 days
Randy is a 19 year old male and has been diagnosed with chlamydia. Which of the
following is the appropriate treatment?
a.) Nitrofurantoin 100 mg by mouth twice daily for 7 days
b.) Doxycycline 100 mg po twice daily for 7 days
c.) Amoxicillin 250 mg by mouth daily for 5 days
d.) Azithromycin 2 g by mouth in a single dose - ANSWER b.) Doxycycline 100 mg
po twice daily for 7 days
Madeline is a 29 year old with genital herpes and would like suppressive therapy.
Which of the following is the appropriate treatment?
a.) Valacyclovir 500 mg by mouth daily for 1 year
b.) Acyclovir 200 mg daily for 6 months
c.) Famciclovir 250mg daily for 6 months
d.) There are no medications for suppressive therapy - ANSWER a.) Valacyclovir
500 mg by mouth daily for 1 year
Treatment for an 18 year old non pregnant female with uncomplicated cervix
infection with gonorrhea and chlamydial infection has not been excluded is:
a.) Ceftriaxone 500 mg IM once
b.) Ceftriaxone 500 mg IM plus Doxycycline 100 mg po twice daily for 7 days
c.) Ceftriaxone 250 mg IM plus Azithromycin 1 gm PO orally
d.) Azithromycin 1 gram by mouth once - ANSWER b.) Ceftriaxone 500 mg IM plus
Doxycycline 100 mg po twice daily for 7 days
Jake a 34 year old male has primary syphilis. What is appropriate treatment?
a.) Doxycycline 100 mg by mouth daily for 7 days
b.) Azithromycin 1 gram by mouth once
c.) Bicillin C-R IM
d.) Benzathine penicillin G (Bicillin LA) IM - ANSWER d.) Benzathine penicillin G
(Bicillin LA) IM
, Lauren a 22 year old female comes into the clinic and is diagnosed with
Trichomoniasis. The NP can prescribe: Check all that apply.
a. ) Metronidazole 500 by mouth twice daily for 7 days
b.) Metronidazole 3 gram by mouth in a single dose
c.) Metronidazole gel 0.75% one full applicator invravaginally once daily for 5 days
d.) Tinidazole 2 gram by mouth in a single dose
e.) Metronidazole 2 gram by mouth in a single dose - ANSWER a. ) Metronidazole
500 by mouth twice daily for 7 days
d.) Tinidazole 2 gram by mouth in a single dose
What do you tell the patient taking metronidazole about drinking alcohol? Check all
that apply.
a.) One glass of wine daily is ok while taking metronidazole
b.) Metronidazole can cause a disulferam-like reaction if taken with alcohol
c.) Alcohol must be avoided completely during treatment and for 72 hours after
treatment
d.) Alcohol can be consumed in moderate amounts - ANSWER b.) Metronidazole
can cause a disulferam-like reaction if taken with alcohol
c.) Alcohol must be avoided completely during treatment and for 72 hours after
treatment
Max is a 70 year old diabetic with shingles. What lab test would you want to order
prior to starting an antivral?
a.) CBC
b.) BUN/Cr
c.) ALT
d.) AST - ANSWER b.) BUN/Cr
Which of the following medications is used for herpes labialis?
a.) Benzocaine gel
b.)Valganciclovir
c.) Penciclovir
d.) Ganciclovir - ANSWER c.) Penciclovir
Which of the following can be given if started within 48 hours of onset of flu
symptoms. Check all that apply.
a. ) Oseltamavir
b.) Zanamivir
c.) Ribavirin
d.) Telbivudine - ANSWER a. ) Oseltamavir
b.) Zanamivir
Which of the following antivirals does the CDC no longer recommend for flu due to
resistance?
a. ) Zanamivir
b.) Amantadine
c.) Oseltamivir
d.) peramivir - ANSWER b.) Amantadine
What is the first drug given for HIV prophylaxis?
