Advanced Pharmacology Final Exam
3 antibiotics for Uncomplicated Cystitis (premenopausal, sexually active,
nonpregnant) - ANSWER Bactrim (TMP-SMZ) 3 days
Macrobid 5 days
Fosfomycin 3g x 1
2nd line antibiotics for uncomplicated cystitis if refractory to 1st line: - ANSWER
Ciprofloxacin
Levaquin
for 3 days
Antibiotics for complicated cystitis (symptoms > 7 days) - ANSWER Ciprofloxacin
Levaquin
for 7 days
Timeframe to begin antibiotic therapy for UTI - ANSWER within 72 hours of
symptoms
medications for UTI symptom relief of spasms - ANSWER Pyridium 200mg TID
Flavoxate 100-200mg TID-QID
genitourinary infection requiring 4-12 weeks of fluoroquinolones (broad spectrum) -
ANSWER prostatitis (usually gram negative)
E.coli & Pseudomonas are gram ( ) organisms - ANSWER gram negative
Staph & Strep are gram ( ) organisms - ANSWER gram positive
prostatitis with STI treated with - ANSWER Rocephin or
Cefixime + Doxycycline
prostatitis without presence of STI is treated with - ANSWER Ciprofloxacin or
Levaquin x 10-14 days (same as uncomplicated pyelonephritis)
1st line treatment for BPH (drug class) - ANSWER a-adrenergic blockers (relax
smooth prostate muscle)
a-adrenergic blockers may have this systemic effect - ANSWER hypotension
Two 1st generation a-adrenergic blockers - ANSWER Terazosin & Doxazosin
Two 2nd generation a-adrenergic blockers - ANSWER Flomax & Rapaflo
, What is the main difference between 1st and 2nd generation a-adrenergic blockers
that treat benign prostatic hyperplasia - ANSWER 1st generation has increased
risk of hypotension
Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery is an adverse
reaction of which medication - ANSWER 1st & 2nd generation a-adrenergic
blockers for BPH
2nd line treatment of BPH (drug class) - ANSWER 5A reductase inhibitors - block
testosterone conversion
Two 5a reductase inhibitors (slow/months to take affect): - ANSWER Proscar,
Avodart
which medications are recommendation are recommended if prostate > 40g? -
ANSWER Proscar, Avodart
which is an inflammatory marker of the prostate? - ANSWER PSA
Possible side effects of Proscar, Avodart: - ANSWER PSA level suppression
(reduces up to 50% after 6 months), risk of prostate CA
Score card for BPH treatment guidelines - ANSWER AUA/IPSS (American
Urological Association /International Prostate Symptom Score)
number ranges for mild, moderate, severe BPH (7 questions with 0-5 points each) -
ANSWER 0-7 mild (may not require tx)
8-19 moderate
20-35 severe
3rd line treatment for BPH - ANSWER combo of 1st and 2nd (most effective) such
as dutasteride (avodart) / tamsulosin OR
may treat with a PD5 inhibitor
1st line treatment for ED (drug class): PD5 inhibitors - ANSWER ED is usually
multi-factorial and patients should be counseled on life-style changes in addition to
Rx.
names of first line meds for ED - ANSWER viagra
levitra
cialis (longer half-life)
stendra (15-min onset)
Adverse reaction of PD5 inhibitors - ANSWER dyspepsia,
headache & flushing
due to the vasodilation
PD5 inhibitors are contraindicated with:
3 antibiotics for Uncomplicated Cystitis (premenopausal, sexually active,
nonpregnant) - ANSWER Bactrim (TMP-SMZ) 3 days
Macrobid 5 days
Fosfomycin 3g x 1
2nd line antibiotics for uncomplicated cystitis if refractory to 1st line: - ANSWER
Ciprofloxacin
Levaquin
for 3 days
Antibiotics for complicated cystitis (symptoms > 7 days) - ANSWER Ciprofloxacin
Levaquin
for 7 days
Timeframe to begin antibiotic therapy for UTI - ANSWER within 72 hours of
symptoms
medications for UTI symptom relief of spasms - ANSWER Pyridium 200mg TID
Flavoxate 100-200mg TID-QID
genitourinary infection requiring 4-12 weeks of fluoroquinolones (broad spectrum) -
ANSWER prostatitis (usually gram negative)
E.coli & Pseudomonas are gram ( ) organisms - ANSWER gram negative
Staph & Strep are gram ( ) organisms - ANSWER gram positive
prostatitis with STI treated with - ANSWER Rocephin or
Cefixime + Doxycycline
prostatitis without presence of STI is treated with - ANSWER Ciprofloxacin or
Levaquin x 10-14 days (same as uncomplicated pyelonephritis)
1st line treatment for BPH (drug class) - ANSWER a-adrenergic blockers (relax
smooth prostate muscle)
a-adrenergic blockers may have this systemic effect - ANSWER hypotension
Two 1st generation a-adrenergic blockers - ANSWER Terazosin & Doxazosin
Two 2nd generation a-adrenergic blockers - ANSWER Flomax & Rapaflo
, What is the main difference between 1st and 2nd generation a-adrenergic blockers
that treat benign prostatic hyperplasia - ANSWER 1st generation has increased
risk of hypotension
Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery is an adverse
reaction of which medication - ANSWER 1st & 2nd generation a-adrenergic
blockers for BPH
2nd line treatment of BPH (drug class) - ANSWER 5A reductase inhibitors - block
testosterone conversion
Two 5a reductase inhibitors (slow/months to take affect): - ANSWER Proscar,
Avodart
which medications are recommendation are recommended if prostate > 40g? -
ANSWER Proscar, Avodart
which is an inflammatory marker of the prostate? - ANSWER PSA
Possible side effects of Proscar, Avodart: - ANSWER PSA level suppression
(reduces up to 50% after 6 months), risk of prostate CA
Score card for BPH treatment guidelines - ANSWER AUA/IPSS (American
Urological Association /International Prostate Symptom Score)
number ranges for mild, moderate, severe BPH (7 questions with 0-5 points each) -
ANSWER 0-7 mild (may not require tx)
8-19 moderate
20-35 severe
3rd line treatment for BPH - ANSWER combo of 1st and 2nd (most effective) such
as dutasteride (avodart) / tamsulosin OR
may treat with a PD5 inhibitor
1st line treatment for ED (drug class): PD5 inhibitors - ANSWER ED is usually
multi-factorial and patients should be counseled on life-style changes in addition to
Rx.
names of first line meds for ED - ANSWER viagra
levitra
cialis (longer half-life)
stendra (15-min onset)
Adverse reaction of PD5 inhibitors - ANSWER dyspepsia,
headache & flushing
due to the vasodilation
PD5 inhibitors are contraindicated with:
