STRUCTURE OF ENZYME
Primary Structure
• The primary structure refers to the sequence of amino acids in
an enzyme.
• Amino acids are linked by peptide bonds.
• Peptide bond formed by the amino group of one amino acid and
COOH group of another amino acid.
Secondary structure
• Secondary structure refers to the interaction of amino acids
amino acids in a chain. It is of two types helical and beta pleated
sheets.
• It is a right-handed alpha helix.
• Intramolecular hydrogen bond is present between O atom of C=O
and N-H group.
• There are 3.6 amino acids per turn of the helix. The pitch of the
helix is 5.4 Å.
• Beta pleated sheet structure is formed by the intermolecular
hydrogen bond.
Tertiary structure
• It is a 3D structure.
• The protein molecules arrange itself in 3-D, so as to obtain
maximum stability and low energy.
• Various interactions involved like H-bonding, polar-polar
interaction, hydrophobic interaction, ionic interaction, formation
of disulphide bonds, Vander Waals forces.
Primary Structure
• The primary structure refers to the sequence of amino acids in
an enzyme.
• Amino acids are linked by peptide bonds.
• Peptide bond formed by the amino group of one amino acid and
COOH group of another amino acid.
Secondary structure
• Secondary structure refers to the interaction of amino acids
amino acids in a chain. It is of two types helical and beta pleated
sheets.
• It is a right-handed alpha helix.
• Intramolecular hydrogen bond is present between O atom of C=O
and N-H group.
• There are 3.6 amino acids per turn of the helix. The pitch of the
helix is 5.4 Å.
• Beta pleated sheet structure is formed by the intermolecular
hydrogen bond.
Tertiary structure
• It is a 3D structure.
• The protein molecules arrange itself in 3-D, so as to obtain
maximum stability and low energy.
• Various interactions involved like H-bonding, polar-polar
interaction, hydrophobic interaction, ionic interaction, formation
of disulphide bonds, Vander Waals forces.
