D027 -ANTIHYPERTENSIVE DRUGS
QUESTIONS AND ANSWERS WITH
VERIFIED SOLUTIONS 2024
Calcium Channel Blockers - ANSWER -dipine
Blocks calcium ions from entering smooth muscle therefore promoting vasodilation
Lower peripheral resistance
Side effects: flushed skin, HA, Constipation and ED, peripheral edema
ACE inhibitors - ANSWER -pril
Angiotensine Coverting Enzeyme Inhibitors
Reduce peripheral resistance by working with the RAAS system by block ACE which stops angiotensine I
from converting to angiotensine II. normally stimulates aldosterone production causing reabsorption of
Na and water causing increased blood volume.
Also stops bradykinin breakdown increasing vasodilation instead of constriction
ARBs - ANSWER -sartan
Angiotensine II receptor blockers
Blocks AT II from binding stopping the vasoconstriction therefore reducing peripheral resistance
Side effects - angiodemia, orthostatic hypotension, hyperkalemia
QUESTIONS AND ANSWERS WITH
VERIFIED SOLUTIONS 2024
Calcium Channel Blockers - ANSWER -dipine
Blocks calcium ions from entering smooth muscle therefore promoting vasodilation
Lower peripheral resistance
Side effects: flushed skin, HA, Constipation and ED, peripheral edema
ACE inhibitors - ANSWER -pril
Angiotensine Coverting Enzeyme Inhibitors
Reduce peripheral resistance by working with the RAAS system by block ACE which stops angiotensine I
from converting to angiotensine II. normally stimulates aldosterone production causing reabsorption of
Na and water causing increased blood volume.
Also stops bradykinin breakdown increasing vasodilation instead of constriction
ARBs - ANSWER -sartan
Angiotensine II receptor blockers
Blocks AT II from binding stopping the vasoconstriction therefore reducing peripheral resistance
Side effects - angiodemia, orthostatic hypotension, hyperkalemia
