DH 75 Pharm midterm #2 Review Part 2
1. What are antieoplastic Malignancies/Cancer
drugs used to treat? Autoimmune disorders
2. What are the different Surgical intervention
modalities of cancer thera- radiation
py? chemotherapy
immunotherapy
hormone therapy
stem cell transplant
3. What is the most common Squamous cell carcinomas
cancer cell found in the
head and neck?
4. What are the 3 drug related opioide overdose
emergencies in a dental of- reaction to local anesthetic agents
fice? epinephrine
5. Mechanism of action of An- interfere with metabolism or the reproductive
tineoplastic agents? cycle of tumor cells
6. Are most antineoplastic Cell cycle specific
agents cell cycle specific or
nonspecific?
7. Antineoplastic drugs must a high kill rate of tumor cells to be effective
have what? -multiple doses are needed and varying treat-
ment types are needed to combat resistance
8. What is Tamoxifen used manage and prevent breast cancer
for?
9. What is the biggest prob- lack of selectivity between tumor tissue and
lem of antineoplastic drug normal tissue
effects? -kills the good cells too
10. Adverse drug effects of an- bone marrow suppression, osteonecrosis, oral
itineoplastic agents? effects
11.
1/7
, DH 75 Pharm midterm #2 Review Part 2
What is the adverse effect mostly seen in intravenous bisphosphonates
of bisphosphonates? (94%)
-high % of causing osteonecrosis of the jaw
12. Risk factors of taking bis- -higher incidence with IV over oral
phosphonates? -taken more than 2 years
-65+ is more susceptible
13. Nausea and vomiting can Prochlorperazine (Compazine)
be controlled by prescrip-
tion of what?
14. Oral effects of antineoplas- xerostomia
tic drugs? glossitis/mucositis
15. What are immunosuppres- organ transplants
sants used for?
16. Common Immunosuppre- Azathioprine (Imuran)
sants: Cyclosporine (Sandimmune)
Tacrolimus (Prograf)
17. Dental issues with Cyl- -monitor BP
cosporine (Sandimmune) -gingival enlargement
-good oral hygiene is important
18. Medical Emergencies asso- syncope
ciated with loss of con- hypoglycemia
sciousness diabetic coma
hyperglycemia
convulsions or seizures
19. Respiratory Emergencies Hyperventilation
asthma
anaphylactic shock
acute airway obstruction
20. Agonal breathing is what Cardiovascular System
kind of med emerg?
2/7
1. What are antieoplastic Malignancies/Cancer
drugs used to treat? Autoimmune disorders
2. What are the different Surgical intervention
modalities of cancer thera- radiation
py? chemotherapy
immunotherapy
hormone therapy
stem cell transplant
3. What is the most common Squamous cell carcinomas
cancer cell found in the
head and neck?
4. What are the 3 drug related opioide overdose
emergencies in a dental of- reaction to local anesthetic agents
fice? epinephrine
5. Mechanism of action of An- interfere with metabolism or the reproductive
tineoplastic agents? cycle of tumor cells
6. Are most antineoplastic Cell cycle specific
agents cell cycle specific or
nonspecific?
7. Antineoplastic drugs must a high kill rate of tumor cells to be effective
have what? -multiple doses are needed and varying treat-
ment types are needed to combat resistance
8. What is Tamoxifen used manage and prevent breast cancer
for?
9. What is the biggest prob- lack of selectivity between tumor tissue and
lem of antineoplastic drug normal tissue
effects? -kills the good cells too
10. Adverse drug effects of an- bone marrow suppression, osteonecrosis, oral
itineoplastic agents? effects
11.
1/7
, DH 75 Pharm midterm #2 Review Part 2
What is the adverse effect mostly seen in intravenous bisphosphonates
of bisphosphonates? (94%)
-high % of causing osteonecrosis of the jaw
12. Risk factors of taking bis- -higher incidence with IV over oral
phosphonates? -taken more than 2 years
-65+ is more susceptible
13. Nausea and vomiting can Prochlorperazine (Compazine)
be controlled by prescrip-
tion of what?
14. Oral effects of antineoplas- xerostomia
tic drugs? glossitis/mucositis
15. What are immunosuppres- organ transplants
sants used for?
16. Common Immunosuppre- Azathioprine (Imuran)
sants: Cyclosporine (Sandimmune)
Tacrolimus (Prograf)
17. Dental issues with Cyl- -monitor BP
cosporine (Sandimmune) -gingival enlargement
-good oral hygiene is important
18. Medical Emergencies asso- syncope
ciated with loss of con- hypoglycemia
sciousness diabetic coma
hyperglycemia
convulsions or seizures
19. Respiratory Emergencies Hyperventilation
asthma
anaphylactic shock
acute airway obstruction
20. Agonal breathing is what Cardiovascular System
kind of med emerg?
2/7
