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Menopause - Correct Answer is the permanent cessation of menses occurring as a
result of loss of ovarian hormone production. It is retrospectively defined as the absence
of menses for 1 year due to hyper gonadotropic hypoestrogenism.
*Menopause*
The median age of naturally occurring menopause is 51.4 years. Ninety percent of
women experience menopause between the ages of 45 to 55 years. - Correct Answer
-Although the average age at which menopause
occurs is stable worldwide, it is influenced in individuals by genetic predisposition and
any events that reduce the ovarian follicle pool.
-Premature menopause or premature ovarian failure is defined as the permanent
cessation of menses occurring before 40 years of age as a result of loss of ovarian
function.
-Menopause can be spontaneous or induced by surgery, chemotherapy, radiation, or
other exogenous
influences.
*Per menopause*
1. The per menopause is the time prior to menopause which is marked by hormonal
changes in the hypothalamic-pituitary-ovarian axis. Clinically, a woman may notice
menstrual cycle changes and *symptoms such as hot flushes and night sweats.*
Physiologically, there are wide fluctuations in follicle-stimulating hormone (FSH)
secretion and estradiol production. - Correct Answer 2. On average, the per
menopause occurs for 4 years prior to menopause. Although hormonal
changes occur, not all women will experience changes in their menstrual pattern. In
fact, approximately 10% of women maintain regular menses up to the point of
menopause.
Post menopause - Correct Answer begins with the final menstrual period (FMP) and
continues for the duration of the woman's life.
PHYSIOLOGY OF PERIMENOPAUSE - Correct Answer Ovulatory cycles diminish
and, although fertility is reduced, pregnancy can occur. The percentage of normal eggs
released is extremely low, explaining the decline in fecundity and increases in
miscarriage and aneuploidy in the premenopausal age group.
Endocrinology of per menopause - Correct Answer 1. Inhibit is produced by the ovary
and exerts a negative feedback on secretion of FSH from the pituitary.
, Levels of inhibit B are reduced with ovarian aging leading to an overall increase in FSH
levels.
Menstrual cycles of per menopause - Correct Answer
Endocrinology of Menopause - Correct Answer
Endocrinology of Menopause Part 2 - Correct Answer
Premature menopause or premature ovarian failure - Correct Answer
Menopause is characterized by amenorrhea - Correct Answer Women may also
experience hot flushes, night
sweats, mood disturbances, headaches, and sexual dysfunction
*Menopause*
Cessation of menses for a minimum of 12 months as a result of cessation of follicular
development. Average age of onset is 51. "Premature menopause" is defined as
ovarian failure and menstrual cessation before age 40. - Correct Answer
Menopause Hex/ PE - Correct Answer HISTORY/PE
■ The mnemonic HAVOC lists prominent features of menopause.
■ Other symptoms include insomnia, anxiety/irritability, vaginal bleeding, poor
concentration, mood changes, dyspareunia, and loss of libido.
Menopause Ds - Correct Answer DIAGNOSIS
■ Labs first show ↑ FSH and then show ↑ LH.
■ DEXA scan to follow bone density for osteoporosis.
■ Lipid profile (↑ total cholesterol, ↓ HDL).
Once a woman is postmenopausal, she should
be routinely screened for - Correct Answer osteoporosis
Menopause Tx - Correct Answer
Effect of estrogen deficiency - Correct Answer
Symptoms of Menopause - Correct Answer
Symptoms of Estrogen Def. - Correct Answer
Estrogen in the body - Correct Answer
Estrogen def. - Correct Answer
Bone mineral density (BMD) - Correct Answer