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Which definition best describes a lead compound? - Correct Answer The first compound discovered
to have the desired activity
Which method of discovering a drug is generally the least expensive? - Correct Answer molecular
docking
What is the name of the process that involves step-wise alteration of a drug to improve its
properties? - Correct Answer structure activity relationship
What was the estimated research and development expenses of pharma in 2016? - Correct Answer
60 billion
Which branch of pharmacology studies the effect of the body on drugs? - Correct Answer
Pharmacokinetics
Which branch of pharmacology studies how patients respond differently to drugs? - Correct Answer
pharmacogenetics
Which branch of pharmacology studies the desired effect of drugs on the body, usually at the
molecular level? - Correct Answer Pharmacodynamics
Which branch of pharmacology studies adverse effects of drugs on the body? - Correct Answer
Toxicology
Which branch of pharmacology does excretion fall under? - Correct Answer Pharmacokinetics
Which is the chemical name for a popular OTC painkiller? - Correct Answer N-acetyl-para-
aminophenol
Which is the proprietary name for a popular OTC painkiller? - Correct Answer Tylenol
Which is the non-proprietary name for a popular OTC painkiller? - Correct Answer acetaminophen
, Which of the following are OTC drugs in the U.S.? Select all that apply. - Correct Answer
Diphenhydramine
Loperamide
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride
Which of the following are only available as prescription drugs in the U.S.? Select all that apply -
Correct Answer Codeine
Levothyroxine
Tadalafil
Sally receives a year-long prescription from her physician for low-dose codeine that allows for 11
refills. Her pharmacist will refuse to honor the full prescription because this is a schedule ___
controlled substance. - Correct Answer III
Which stage of translational research is the first to utilize a FDA approved drug? - Correct Answer T3
For which of the following parts of translational research is patient involvement critical? Choose all
that apply - Correct Answer Public health
Basic research
Pre-clinical research
Clinical research
Clinical implementation
The transition between which two phases of translational research involves switching from
controlled settings to real-world settings? - Correct Answer T2-T3
Which type of drug is most likely to be given orally? - Correct Answer small molecule
Overnight contact lenses are considered class ___ medical devices. - Correct Answer Class III
What term describes the process of taking a piece of human tumor from a patient and placing it
under the skin of a mouse in order to do pre-clinical testing? - Correct Answer Patient-derived
xenograft