GMS 6551 Drug Studies with Complete Solutions 100% Verified

GMS 6551 Drug Studies with Complete Solutions
100% Verified
Drug targets - Correct Answer - enzymes

- receptors

- proteins

- DNA

- RNA

- carbohydrates

- lipids



Bacterial enzymes - Correct Answer - easier to target than human proteins



In vitro - Correct Answer - fast

- cheap

- test tube



In vivo - Correct Answer - complex

- expensive

- may mask things seen in test tube

- harmful to animals



Lead compound - Correct Answer - first compound that has deisred activity



SAR - Correct Answer - structure activity relationships

- optimize lead compounds

- makes drug better

- elimation of unneeded effects



Pharmacokinetics - Correct Answer - dose given & how often

- absorption

, - distribution

- metabolism

- excretion

- determined in vitro or in vivo



Pharmacodynamics - Correct Answer - what drug does to the body

- MOA

- potentcy

- efficacy

- toxicity



Pharmacogenetics - Correct Answer - how genetic makup impacts drug function



Pharmacotherapeutics - Correct Answer - how drugs are clinically used



Main targets - Correct Answer - receptors

- enzymes



Drug classification - Correct Answer - chemical properties (benzos)

- MOA (ACEI)

- disease or condition used to treat (analgesics)

- abuse potential

1) OTC

2) Prescription

3) Orphan drugs



Orpan drugs - Correct Answer - used to treat rare diseases

- usually funded by government



Schedule I - Correct Answer - high abuse potential

- no medical use