GMS 6551 Homework Questions with Correct
Answers
Which definition best describes a lead compound? - Correct Answer The first compound discovered
to have the desired activity
Which method of discovering a drug is generally the least expensive? - Correct Answer Molecular
docking
What is the name of the process that involves step-wise alteration of a drug to improve its
properties? - Correct Answer Structure activity relationship
What was the estimated research and development expenses of pharma in 2016? - Correct Answer
60 billion
Which branch of pharmacology studies the effect of the body on drugs? - Correct Answer
Pharmacokinetics
Which branch of pharmacology studies how patients respond differently to drugs? - Correct Answer
Pharmacogenetics
Which branch of pharmacology studies the desired effect of drugs on the body, usually at the
molecular level? - Correct Answer Pharmacodynamics
Which branch of pharmacology studies adverse effects of drugs on the body? - Correct Answer
Toxicology
Which branch of pharmacology does excretion fall under? - Correct Answer Pharmacokinetics
Which is the chemical name for a popular OTC painkiller? - Correct Answer N-acetyl-para-
aminophenol
Which is the proprietary name for a popular OTC painkiller? - Correct Answer Tylenol
Which is the non-proprietary name for a popular OTC painkiller? - Correct Answer Acetaminophen
, Which of the following are OTC drugs in the U.S.? Select all that apply. - Correct Answer
Diphenhydramine, Loperamide, and 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-
dimethylphenol;hydrochloride
Which of the following are prescription drugs in the U.S.? Select all that apply. - Correct Answer
Codeine, levothyroxine, and Tadalafil
Sally receives a year-long prescription from her physician for low-dose codeine that allows for 11
refills. Her pharmacist will refuse to honor the full prescription because this is a schedule ___
controlled substance. - Correct Answer III
Which stage of translational research is the first to utilize a FDA approved drug? - Correct Answer T3
For which of the following parts of translational research is patient involvement critical? Choose all
that apply. - Correct Answer Public Health, Basic Research, Pre-Clinical Research, Clinical Research,
and Clinical Implementation
The transition between which two phases of translational research involves switching from
controlled settings to real-world settings? - Correct Answer T2-T3
Which type of drug is most likely to be given orally? - Correct Answer Small molecule
Overnight contact lenses are considered class ___ medical devices. - Correct Answer Class III
What term describes the process of taking a piece of human tumor from a patient and placing it
under the skin of a mouse in order to do pre-clinical testing? - Correct Answer Patient-derived
xenograft
In order to do a clinical trial in humans, IRB approval must be obtained. From which regulatory body
must approval be obtained in order to carry out a similar study in rats? - Correct Answer IACUC
Gaining information on which of the following is the primary purpose of a Phase I clinical trial? -
Correct Answer Treatment safety
Answers
Which definition best describes a lead compound? - Correct Answer The first compound discovered
to have the desired activity
Which method of discovering a drug is generally the least expensive? - Correct Answer Molecular
docking
What is the name of the process that involves step-wise alteration of a drug to improve its
properties? - Correct Answer Structure activity relationship
What was the estimated research and development expenses of pharma in 2016? - Correct Answer
60 billion
Which branch of pharmacology studies the effect of the body on drugs? - Correct Answer
Pharmacokinetics
Which branch of pharmacology studies how patients respond differently to drugs? - Correct Answer
Pharmacogenetics
Which branch of pharmacology studies the desired effect of drugs on the body, usually at the
molecular level? - Correct Answer Pharmacodynamics
Which branch of pharmacology studies adverse effects of drugs on the body? - Correct Answer
Toxicology
Which branch of pharmacology does excretion fall under? - Correct Answer Pharmacokinetics
Which is the chemical name for a popular OTC painkiller? - Correct Answer N-acetyl-para-
aminophenol
Which is the proprietary name for a popular OTC painkiller? - Correct Answer Tylenol
Which is the non-proprietary name for a popular OTC painkiller? - Correct Answer Acetaminophen
, Which of the following are OTC drugs in the U.S.? Select all that apply. - Correct Answer
Diphenhydramine, Loperamide, and 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-
dimethylphenol;hydrochloride
Which of the following are prescription drugs in the U.S.? Select all that apply. - Correct Answer
Codeine, levothyroxine, and Tadalafil
Sally receives a year-long prescription from her physician for low-dose codeine that allows for 11
refills. Her pharmacist will refuse to honor the full prescription because this is a schedule ___
controlled substance. - Correct Answer III
Which stage of translational research is the first to utilize a FDA approved drug? - Correct Answer T3
For which of the following parts of translational research is patient involvement critical? Choose all
that apply. - Correct Answer Public Health, Basic Research, Pre-Clinical Research, Clinical Research,
and Clinical Implementation
The transition between which two phases of translational research involves switching from
controlled settings to real-world settings? - Correct Answer T2-T3
Which type of drug is most likely to be given orally? - Correct Answer Small molecule
Overnight contact lenses are considered class ___ medical devices. - Correct Answer Class III
What term describes the process of taking a piece of human tumor from a patient and placing it
under the skin of a mouse in order to do pre-clinical testing? - Correct Answer Patient-derived
xenograft
In order to do a clinical trial in humans, IRB approval must be obtained. From which regulatory body
must approval be obtained in order to carry out a similar study in rats? - Correct Answer IACUC
Gaining information on which of the following is the primary purpose of a Phase I clinical trial? -
Correct Answer Treatment safety
