I Basic Principles General Aspects of Medical 1
Microbiology
Basic Principles of Immunology 2
II Bacteriology General Bacteriology 3
Bacteria as Human Pathogens 4
III Mycology General Mycology 5
Fungi as Human Pathogens 6
IV Virology General Virology 7
Viruses as Human Pathogens 8
V Parasitology Protozoa 9
Helminths 10
Arthropods 11
VI Organ System Etiological and Laboratory 12
Infections Diagnostic Summaries in
Tabular Form
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
,II
At a Glance…
The book is divided into six main sections. The color-coded reference guide
on the first page will help you find what you need.
The aspects of each pathogen are covered systematically, using the following
order wherever practicable:
& Classification & Pathogenesis and Clinical Picture
& Localization & Diagnosis
& Morphology and Culturing & Therapy
& Developmental Cycle & Epidemiology and Prophylaxis
& A summary at the beginning of a chapter or section provides a quick over-
view of what the main text covers. Students can use the summaries to obtain
a quick recapitulation of the main points. &
The Main Sections at a Glance
a The many colored illustrations
serve to clarify complex topics or
provide definitive impressions of
pathogen morphology.
b The header caption above each
illustration gives the reader the es-
sence of what is shown.
c The detailed legends explain the
illustrations independently of the
main text.
Additional information
In-depth expositions and supplementary knowledge are framed in boxes inter-
spersed throughout the main body of text. The headings outline the topic covered,
enabling the reader to decide whether the specific material is needed at the present
time.
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
,Medical Microbiology
Fritz H. Kayser, M.D.
Emeritus Professor of Medical Microbiology
Institute of Medical Microbiology
University of Zurich
Zurich, Switzerland
Kurt A. Bienz, Ph.D.
Emeritus Professor of Virology
Institute of Medical Microbiology
University of Basle
Basle, Switzerland
Johannes Eckert, D.V.M.
Emeritus Professor of Parasitology
Institute of Parasitology
University of Zurich
Zurich, Switzerland
Rolf M. Zinkernagel, M.D.
Professor
Institute of Experimental Immunology
Department of Pathology
Zurich, Switzerland
177 illustrations
97 tables
Thieme
Stuttgart ! New York
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
All rights reserved. Usage subject to terms and conditions of license
, Library of Congress Cataloging-in- Important note: Medicine is an ever-chan-
Publication Data ging science undergoing continual develop-
Medizinische Mikrobiologie. English. ment. Research and clinical experience are
Medical microbiology / Fritz H. Kayser ... continually expanding our knowledge, in
[et al.]. p. ; cm. particular our knowledge of proper treat-
ISBN 3-13-131991-7 (GTV : alk. paper) – ment and drug therapy. Insofar as this
ISBN 1-58890-245-5 (TNY ; alk. paper) book mentions any dosage or application,
1. Medical microbiology. readers may rest assured that the authors,
[DNLM: 1. Microbiology. QW 4 M491 editors, and publishers have made every
2005a] I. Kayser, F. H. (Fritz H.) II. Title. effort to ensure that such references are in
QR46.M48813 2005 accordance with the state of knowledge
616.9’041–dc22 2004021965 at the time of production of the book.
Nevertheless, this does not involve, imply,
1st German edition 1969 or express any guarantee or responsibility on
2nd German edition 1971 the part of the publishers in respect to any
3rd German edition 1974 dosage instructions and forms of applica-
4th German edition 1978 tions stated in the book. Every user is re-
5th German edition 1982 quested to examine carefully the manufac-
6th German edition 1986 turers’ leaflets accompanying each drug and
7th German edition 1989 to check, if necessary in consultation with a
8th German edition 1993 physician or specialist, whether the dosage
9th German edition 1998 schedules mentioned therein or the contra-
1st Greek edition 1995 indications stated by the manufacturers dif-
fer from the statements made in the present
1st Italian edition 1996
book. Such examination is particularly im-
1st Japanese edition 1980 portant with drugs that are either rarely
1st Spanish edition 1974 used or have been newly released on the
2nd Spanish edition 1982 market. Every dosage schedule or every
1st Turkish edition 2001 form of application used is entirely at the
user’s own risk and responsibility. The
This book is an authorized and updated authors and publishers request every user
translation of the 10th German edition to report to the publishers any discrepancies
published and copyrighted 2001 or inaccuracies noticed.
by Georg Thieme Verlag, Stuttgart, Some of the product names, patents, and
Germany. Title of the German edition: registered designs referred to in this book
Medizinische Mikrobiologie are in fact registered trademarks or proprie-
tary names even though specific reference to
ª 2005 Georg Thieme Verlag, this fact is not always made in the text.
Rüdigerstraße 14, 70469 Stuttgart, Therefore, the appearance of a name without
Germany designation as proprietary is not to be con-
http://www. thieme.de strued as a representation by the publisher
Thieme New York, 333 Seventh Avenue, that it is in the public domain.
New York, NY 10001 USA This book, including all parts thereof, is
http://www.thieme.com legally protected by copyright. Any use, ex-
Cover design: Cyclus, Stuttgart ploitation, or commercialization outside the
narrow limits set by copyright legislation,
Typesetting by Mitterweger & Partner
without the publisher’s consent, is illegal
GmbH, 68723 Plankstadt
and liable to prosecution. This applies in par-
Printed in Germany by Appl, Wemding
ticular to photostat reproduction, copying,
ISBN 3-13-131991-7 (GTV) mimeographing, preparation of microfilms,
ISBN 1-58890-245-5 (TNY) 12345 and electronic data processing and storage.
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
All rights reserved. Usage subject to terms and conditions of license
Microbiology
Basic Principles of Immunology 2
II Bacteriology General Bacteriology 3
Bacteria as Human Pathogens 4
III Mycology General Mycology 5
Fungi as Human Pathogens 6
IV Virology General Virology 7
Viruses as Human Pathogens 8
V Parasitology Protozoa 9
Helminths 10
Arthropods 11
VI Organ System Etiological and Laboratory 12
Infections Diagnostic Summaries in
Tabular Form
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
,II
At a Glance…
The book is divided into six main sections. The color-coded reference guide
on the first page will help you find what you need.
The aspects of each pathogen are covered systematically, using the following
order wherever practicable:
& Classification & Pathogenesis and Clinical Picture
& Localization & Diagnosis
& Morphology and Culturing & Therapy
& Developmental Cycle & Epidemiology and Prophylaxis
& A summary at the beginning of a chapter or section provides a quick over-
view of what the main text covers. Students can use the summaries to obtain
a quick recapitulation of the main points. &
The Main Sections at a Glance
a The many colored illustrations
serve to clarify complex topics or
provide definitive impressions of
pathogen morphology.
b The header caption above each
illustration gives the reader the es-
sence of what is shown.
c The detailed legends explain the
illustrations independently of the
main text.
Additional information
In-depth expositions and supplementary knowledge are framed in boxes inter-
spersed throughout the main body of text. The headings outline the topic covered,
enabling the reader to decide whether the specific material is needed at the present
time.
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
,Medical Microbiology
Fritz H. Kayser, M.D.
Emeritus Professor of Medical Microbiology
Institute of Medical Microbiology
University of Zurich
Zurich, Switzerland
Kurt A. Bienz, Ph.D.
Emeritus Professor of Virology
Institute of Medical Microbiology
University of Basle
Basle, Switzerland
Johannes Eckert, D.V.M.
Emeritus Professor of Parasitology
Institute of Parasitology
University of Zurich
Zurich, Switzerland
Rolf M. Zinkernagel, M.D.
Professor
Institute of Experimental Immunology
Department of Pathology
Zurich, Switzerland
177 illustrations
97 tables
Thieme
Stuttgart ! New York
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
All rights reserved. Usage subject to terms and conditions of license
, Library of Congress Cataloging-in- Important note: Medicine is an ever-chan-
Publication Data ging science undergoing continual develop-
Medizinische Mikrobiologie. English. ment. Research and clinical experience are
Medical microbiology / Fritz H. Kayser ... continually expanding our knowledge, in
[et al.]. p. ; cm. particular our knowledge of proper treat-
ISBN 3-13-131991-7 (GTV : alk. paper) – ment and drug therapy. Insofar as this
ISBN 1-58890-245-5 (TNY ; alk. paper) book mentions any dosage or application,
1. Medical microbiology. readers may rest assured that the authors,
[DNLM: 1. Microbiology. QW 4 M491 editors, and publishers have made every
2005a] I. Kayser, F. H. (Fritz H.) II. Title. effort to ensure that such references are in
QR46.M48813 2005 accordance with the state of knowledge
616.9’041–dc22 2004021965 at the time of production of the book.
Nevertheless, this does not involve, imply,
1st German edition 1969 or express any guarantee or responsibility on
2nd German edition 1971 the part of the publishers in respect to any
3rd German edition 1974 dosage instructions and forms of applica-
4th German edition 1978 tions stated in the book. Every user is re-
5th German edition 1982 quested to examine carefully the manufac-
6th German edition 1986 turers’ leaflets accompanying each drug and
7th German edition 1989 to check, if necessary in consultation with a
8th German edition 1993 physician or specialist, whether the dosage
9th German edition 1998 schedules mentioned therein or the contra-
1st Greek edition 1995 indications stated by the manufacturers dif-
fer from the statements made in the present
1st Italian edition 1996
book. Such examination is particularly im-
1st Japanese edition 1980 portant with drugs that are either rarely
1st Spanish edition 1974 used or have been newly released on the
2nd Spanish edition 1982 market. Every dosage schedule or every
1st Turkish edition 2001 form of application used is entirely at the
user’s own risk and responsibility. The
This book is an authorized and updated authors and publishers request every user
translation of the 10th German edition to report to the publishers any discrepancies
published and copyrighted 2001 or inaccuracies noticed.
by Georg Thieme Verlag, Stuttgart, Some of the product names, patents, and
Germany. Title of the German edition: registered designs referred to in this book
Medizinische Mikrobiologie are in fact registered trademarks or proprie-
tary names even though specific reference to
ª 2005 Georg Thieme Verlag, this fact is not always made in the text.
Rüdigerstraße 14, 70469 Stuttgart, Therefore, the appearance of a name without
Germany designation as proprietary is not to be con-
http://www. thieme.de strued as a representation by the publisher
Thieme New York, 333 Seventh Avenue, that it is in the public domain.
New York, NY 10001 USA This book, including all parts thereof, is
http://www.thieme.com legally protected by copyright. Any use, ex-
Cover design: Cyclus, Stuttgart ploitation, or commercialization outside the
narrow limits set by copyright legislation,
Typesetting by Mitterweger & Partner
without the publisher’s consent, is illegal
GmbH, 68723 Plankstadt
and liable to prosecution. This applies in par-
Printed in Germany by Appl, Wemding
ticular to photostat reproduction, copying,
ISBN 3-13-131991-7 (GTV) mimeographing, preparation of microfilms,
ISBN 1-58890-245-5 (TNY) 12345 and electronic data processing and storage.
Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
All rights reserved. Usage subject to terms and conditions of license