HEMATOLOGY EXAM 2 WEEK 3 WITH COMPLETE QUESTIONS AND 100% CORRECT ANSWERS { GRADED A+}

HEMATOLOGY EXAM 2 WEEK 3 WITH

COMPLETE QUESTIONS AND 100%

CORRECT ANSWERS { GRADED A+}




What is macrocytic anemia? - ✔✔Bone marrow produces abnormally large

RBCs, which lack nutrients needed to function normally


Macrocytic anemia is [...] - ✔✔Macrocytic anemia is not a serious illness, but can

cause issues if left untreated


How is macrocytic anemia classified? - ✔✔Classified based on presence of

megaloblasts -> important to determine whether folate of vit B12 deficiency to

provide proper tx


2 causes of megaloblastic macrocytic anemia? - ✔✔1. Folate deficiency


2. Vit B12 (cobalamin) deficiency


4 causes of nonmegaloblastic macrocytic anemia? - ✔✔1. Liver disease

, 2. Alcoholism


3. Reticulocytosis


4. Drugs


Vitamin B12 deficiency - What does B12 do? - ✔✔Serves as cofactor in two

important rxns req for erythropoeisis and CNS functioning:


1. Conversion of homoCys to Met


2. Conversion of MeMalonyl-CoA to succinyl-CoA


Vitamin B12 deficiency - What are the two main dietary sources of B12? -

✔✔Dark meat and fish


Vitamin B12 deficiency - What is the most common causes for deficiency? (5) -

✔✔Commonly from impaired absorption:


1. Pernicious anemia


2. Gastrectomy


3. Inadequate dietary intake


4. Crohns or resection of term ileum


5. Other micro-orgs competing