Cambridge International
A2 Level
Chapter 29: Analytical
Chemistry
CIE A2 Chemistry
, 22.0 Analytical Chemistry
AS Level: 22.2 Infra-red spectroscopy
A Level
22.1 Chromatography
22.3 Mass Spectrometry
22.4 Carbon-13 NMR spectroscopy
22.5 Proton (1H) NMR spectroscopy
CIE A2 Chemistry
, 22.3 Mass Spectrometry
detect the existence of isotopes, their masses and
relative abundances
Identify molecular formula of elements and (organic)
compounds
A substance can be identified by matching its spectrum
against the spectra of known substances in a database –
„fingerprinting‟
CIE A2 Chemistry
, 22.3 Mass Spectrometry of Atoms
Sample struck by high-energy electrons
and breaking molecules apart
X(g) + e- → X•+ (g) + 2e-
The fragments are detected and recorded
as a „stick diagram‟ (mass spectrum)
y axis: relative abundance
x axis: Mr of ion (mass to charge, m/z ratio)
CIE A2 Chemistry
A2 Level
Chapter 29: Analytical
Chemistry
CIE A2 Chemistry
, 22.0 Analytical Chemistry
AS Level: 22.2 Infra-red spectroscopy
A Level
22.1 Chromatography
22.3 Mass Spectrometry
22.4 Carbon-13 NMR spectroscopy
22.5 Proton (1H) NMR spectroscopy
CIE A2 Chemistry
, 22.3 Mass Spectrometry
detect the existence of isotopes, their masses and
relative abundances
Identify molecular formula of elements and (organic)
compounds
A substance can be identified by matching its spectrum
against the spectra of known substances in a database –
„fingerprinting‟
CIE A2 Chemistry
, 22.3 Mass Spectrometry of Atoms
Sample struck by high-energy electrons
and breaking molecules apart
X(g) + e- → X•+ (g) + 2e-
The fragments are detected and recorded
as a „stick diagram‟ (mass spectrum)
y axis: relative abundance
x axis: Mr of ion (mass to charge, m/z ratio)
CIE A2 Chemistry
