Test Bank for Pharmacology and the Nursing Process 10th
Edition By Linda Lilley, Shelly Collins, Julie Snyder Chapter 1-58
| 9780323827973 | All Chapters with Answers and Rationals
When considering the various routes of drug elimination, the nurse is aware the elimination occurs
mainly by which routes ? - ANSWER: Bowel and renal tubes
The nurse is aware that the extensive drug dosage, impaired metabolism, or inadequate excretion
may result in which drug effect? - ANSWER: Cumulative effect
Drug Half-Life is defined as the amount of time required for 50% of a drug to? - ANSWER: Be removed
from the body.
The nurse recognizes that drugs given by which route will be altered by the first pass effect? Choose
all that apply - ANSWER: Oral
Rectal
If a drug binds with an enzyme and thereby prevents the enzyme from binding to its normal Target
cell, it will produce which effect? - ANSWER: Enzyme interaction
The nurse is reviewing a list of patients medications and notes that one of the drugs is known to have
low therapeutic index. Which statement accurately explains this concept? - ANSWER: The difference
between a therapeutic dose and the toxic dose is small.
The nurse prepares to obtain a patient's blood sample from a central line for a drug level that is to be
drawn just before the medicines next dose. What is the timing of this blood draw known as? -
ANSWER: Trough level
A drug has a half life of 4 hours if a toe 800 the drug level is measured at 200 mg at what time would
the drug level be 50 mg? - ANSWER: 1600
When a drug functions as an enzyme inhibitor of another drug the nurse would anticipate what
results in drug B? - ANSWER: levels of drug B could rise to toxicity
When administering a new medication to a patient the nurse notes the drug is highly protein-bound.
The patient's albumin level is normal. When bound, the nurse would expect the protein-bound drug
to? - ANSWER: Have a longer duration of action
The nurse administers warfarin to a patient who is currently taking a second drug that is highly
protein-bound. The nurse knows a drug drug interaction could occur. Which would result in? -
ANSWER: The second drug increasing the action and toxicity of the first drug.
An elderly woman took a prescription medicine to help her to sleep semicolon however, she feels
Restless all night and did not sleep at all. The nurse recognizes that this woman has experienced
which type of reaction or affect? - ANSWER: Idiosyncratic reaction
Well caring for a patient with cirrhosis or hepatitis, the nurse knows that the abnormalities in which
phase of pharmacokinetics may occur? - ANSWER: Metabolism
A patient who had a thyroidectomy is now taking Levothyroxine, I thought I read Hermann, daily.
Which term best describes this type of therapy? - ANSWER: Maintenance therapy
The nurse is giving medications to a patient in heart failure. The intravenous route is chosen instead
of the intramuscular route. What patient function does the nurse recognize as the most influential
,when deciding to use the intravenous route of Drug Administration? - ANSWER: Diminished
circulation
A patient has just received a prescription for an enteric-coated stool softener. When teaching the
patient, the nurse should include which statement? - ANSWER: Be sure to swallow the tablet hole
without chewing it.
the nurse is reviewing the various forms of topical medications. Which of these are considered topical
medications? - ANSWER: Rectal ointment for hemorrhoids
Eye drops for inflammation
Inhaled medication for asthma
What is the study of physiochemical properties of drugs and how they influence the body called? -
ANSWER: Pharmacodynamics
What is another term for biotransformation of a drug? - ANSWER: Metabolism
A drug given by which route is altered by the first-pass effect? - ANSWER: oral
Drug half-life is defined as the amount of time required for 50% of a drug to? - ANSWER: Be
eliminated by the body.
Which nursing action will increase the absorption of a medication administered intramuscularly? -
ANSWER: Massage the site after injection.
When administering two medications that are highly protein bound, the nurse understands to
monitor the patient carefully for which effect? - ANSWER: Increase in the risk of drug-drug
To achieve the most rapid onset of action, the health care provider will prescribe the medication to be
administered by which route? - ANSWER: IV
Patients with renal failure would MOST likely have problems with which pharmacokinetic process? -
ANSWER: Excretion
What is the ratio between a drug's therapeutic effects and toxic effects called? - ANSWER:
Therapeutic index
A patient asks the nurse why a lower dose of IV pain medication is being given than the previous oral
dose. What is the nurse's best response to the patient? - ANSWER: Medications given intravenously
are not affected by the first-pass effect."
The nurse understands that drugs exert their actions on the body by what process? (Select all that
apply.) - ANSWER: Inhibiting the action of a specific enzyme
Altering metabolic chemical processes
Interacting with receptors
Which statement best describes pharmacokinetics? - ANSWER: What the body does to the drug after
it is administered
The nurse knows that which factors will affect the absorption of orally administered medications?
(Select all that apply.) - ANSWER: Presence of food in the stomach
Time of day
, PH of the stomach
Form of drug preparation
additive effects - ANSWER: Drug interactions in which the effect of a combination of two or more
drugs with similar actions is equivalent to the sum of the individual effects of the same drugs given
alone.
adverse drug event - ANSWER: any undesirable occurrence related to administering or failing to
administer a prescribed medication
adverse drug reaction - ANSWER: any unexpected, unintended, undesired, or excessive response to a
medication given at therapeutic dosages (as opposed to overdose)
adverse effects - ANSWER: Any undesirable effects that are a direct response to one or more drugs.
antagonist - ANSWER: a drug that binds to and inhibits the activity of receptors in the body
biotransformation - ANSWER: metabolism
cytochromes - ANSWER: enzymes that play a significant role in drug metabolism and interactions
disillusion - ANSWER: solid forms of drugs disintegrate in the gastrointestinal tract and become solid
will you Bowl before being absorbed into the circulation
drug effects - ANSWER: The physiologic reactions of the body to a drug.
drug-induced teratogenesis - ANSWER: the development of defects in the developing fetus caused by
Toxic effect of drugs
Half-life (t1/2) - ANSWER: the time required for half of an administer dose of drug to be eliminated by
the body or the time it takes for the blood level of a drug to be reduced by 50%
intrathecal - ANSWER: injection into the meningeal space surrounding the brain and spinal cord
medication error - ANSWER: Any preventable adverse drug event involving inappropriate medication
use by a patient or health care professional;
it may or may not cause the patient harm.
The onset of action - ANSWER: The time required for a drug to elicit a therapeutic response
p-glycoprotein - ANSWER: a transporter protein that moves drugs out of cells and into the gut, urine,
or bile
parent drug - ANSWER: The chemical form of a drug that is administered before it is metabolized
Peak effect - ANSWER: the time required for a drug to reach its maximum therapeutic response
pharmacuetics - ANSWER: the science of preparing and dispensing drugs
pharmacodynamics - ANSWER: the study of interactions of drugs at their site of activity
pharmacognosy - ANSWER: The study of drugs that are obtained from natural plant and animal
sources.
Edition By Linda Lilley, Shelly Collins, Julie Snyder Chapter 1-58
| 9780323827973 | All Chapters with Answers and Rationals
When considering the various routes of drug elimination, the nurse is aware the elimination occurs
mainly by which routes ? - ANSWER: Bowel and renal tubes
The nurse is aware that the extensive drug dosage, impaired metabolism, or inadequate excretion
may result in which drug effect? - ANSWER: Cumulative effect
Drug Half-Life is defined as the amount of time required for 50% of a drug to? - ANSWER: Be removed
from the body.
The nurse recognizes that drugs given by which route will be altered by the first pass effect? Choose
all that apply - ANSWER: Oral
Rectal
If a drug binds with an enzyme and thereby prevents the enzyme from binding to its normal Target
cell, it will produce which effect? - ANSWER: Enzyme interaction
The nurse is reviewing a list of patients medications and notes that one of the drugs is known to have
low therapeutic index. Which statement accurately explains this concept? - ANSWER: The difference
between a therapeutic dose and the toxic dose is small.
The nurse prepares to obtain a patient's blood sample from a central line for a drug level that is to be
drawn just before the medicines next dose. What is the timing of this blood draw known as? -
ANSWER: Trough level
A drug has a half life of 4 hours if a toe 800 the drug level is measured at 200 mg at what time would
the drug level be 50 mg? - ANSWER: 1600
When a drug functions as an enzyme inhibitor of another drug the nurse would anticipate what
results in drug B? - ANSWER: levels of drug B could rise to toxicity
When administering a new medication to a patient the nurse notes the drug is highly protein-bound.
The patient's albumin level is normal. When bound, the nurse would expect the protein-bound drug
to? - ANSWER: Have a longer duration of action
The nurse administers warfarin to a patient who is currently taking a second drug that is highly
protein-bound. The nurse knows a drug drug interaction could occur. Which would result in? -
ANSWER: The second drug increasing the action and toxicity of the first drug.
An elderly woman took a prescription medicine to help her to sleep semicolon however, she feels
Restless all night and did not sleep at all. The nurse recognizes that this woman has experienced
which type of reaction or affect? - ANSWER: Idiosyncratic reaction
Well caring for a patient with cirrhosis or hepatitis, the nurse knows that the abnormalities in which
phase of pharmacokinetics may occur? - ANSWER: Metabolism
A patient who had a thyroidectomy is now taking Levothyroxine, I thought I read Hermann, daily.
Which term best describes this type of therapy? - ANSWER: Maintenance therapy
The nurse is giving medications to a patient in heart failure. The intravenous route is chosen instead
of the intramuscular route. What patient function does the nurse recognize as the most influential
,when deciding to use the intravenous route of Drug Administration? - ANSWER: Diminished
circulation
A patient has just received a prescription for an enteric-coated stool softener. When teaching the
patient, the nurse should include which statement? - ANSWER: Be sure to swallow the tablet hole
without chewing it.
the nurse is reviewing the various forms of topical medications. Which of these are considered topical
medications? - ANSWER: Rectal ointment for hemorrhoids
Eye drops for inflammation
Inhaled medication for asthma
What is the study of physiochemical properties of drugs and how they influence the body called? -
ANSWER: Pharmacodynamics
What is another term for biotransformation of a drug? - ANSWER: Metabolism
A drug given by which route is altered by the first-pass effect? - ANSWER: oral
Drug half-life is defined as the amount of time required for 50% of a drug to? - ANSWER: Be
eliminated by the body.
Which nursing action will increase the absorption of a medication administered intramuscularly? -
ANSWER: Massage the site after injection.
When administering two medications that are highly protein bound, the nurse understands to
monitor the patient carefully for which effect? - ANSWER: Increase in the risk of drug-drug
To achieve the most rapid onset of action, the health care provider will prescribe the medication to be
administered by which route? - ANSWER: IV
Patients with renal failure would MOST likely have problems with which pharmacokinetic process? -
ANSWER: Excretion
What is the ratio between a drug's therapeutic effects and toxic effects called? - ANSWER:
Therapeutic index
A patient asks the nurse why a lower dose of IV pain medication is being given than the previous oral
dose. What is the nurse's best response to the patient? - ANSWER: Medications given intravenously
are not affected by the first-pass effect."
The nurse understands that drugs exert their actions on the body by what process? (Select all that
apply.) - ANSWER: Inhibiting the action of a specific enzyme
Altering metabolic chemical processes
Interacting with receptors
Which statement best describes pharmacokinetics? - ANSWER: What the body does to the drug after
it is administered
The nurse knows that which factors will affect the absorption of orally administered medications?
(Select all that apply.) - ANSWER: Presence of food in the stomach
Time of day
, PH of the stomach
Form of drug preparation
additive effects - ANSWER: Drug interactions in which the effect of a combination of two or more
drugs with similar actions is equivalent to the sum of the individual effects of the same drugs given
alone.
adverse drug event - ANSWER: any undesirable occurrence related to administering or failing to
administer a prescribed medication
adverse drug reaction - ANSWER: any unexpected, unintended, undesired, or excessive response to a
medication given at therapeutic dosages (as opposed to overdose)
adverse effects - ANSWER: Any undesirable effects that are a direct response to one or more drugs.
antagonist - ANSWER: a drug that binds to and inhibits the activity of receptors in the body
biotransformation - ANSWER: metabolism
cytochromes - ANSWER: enzymes that play a significant role in drug metabolism and interactions
disillusion - ANSWER: solid forms of drugs disintegrate in the gastrointestinal tract and become solid
will you Bowl before being absorbed into the circulation
drug effects - ANSWER: The physiologic reactions of the body to a drug.
drug-induced teratogenesis - ANSWER: the development of defects in the developing fetus caused by
Toxic effect of drugs
Half-life (t1/2) - ANSWER: the time required for half of an administer dose of drug to be eliminated by
the body or the time it takes for the blood level of a drug to be reduced by 50%
intrathecal - ANSWER: injection into the meningeal space surrounding the brain and spinal cord
medication error - ANSWER: Any preventable adverse drug event involving inappropriate medication
use by a patient or health care professional;
it may or may not cause the patient harm.
The onset of action - ANSWER: The time required for a drug to elicit a therapeutic response
p-glycoprotein - ANSWER: a transporter protein that moves drugs out of cells and into the gut, urine,
or bile
parent drug - ANSWER: The chemical form of a drug that is administered before it is metabolized
Peak effect - ANSWER: the time required for a drug to reach its maximum therapeutic response
pharmacuetics - ANSWER: the science of preparing and dispensing drugs
pharmacodynamics - ANSWER: the study of interactions of drugs at their site of activity
pharmacognosy - ANSWER: The study of drugs that are obtained from natural plant and animal
sources.
