Test Bank for Pharmacology and the Nursing Process 10th
Edition By Linda Lilley, Shelly Collins, Julie Snyder Chapter 1-58
| 9780323827973 | All Chapters with Answers and Rationals
Ch 2
A nurse is administering a drug to clients who have the disease for which a drug is designed to treat.
The nurse is most likely participating in which of the following?
a) Phase III study
b) Phase I study
c) Phase II study
d) Preclinical trial - ANSWER: C
Number the following drug forms in order of speed
of dissolution and absorption, with (1) being the fastest
and (5) being the slowest:
_____ a. Capsules
_____ b. Enteric-coated tablets
_____ c. Elixirs
_____ d. Powders
_____ e. Orally disintegrating tablets - ANSWER: E, C, D, A, B
What are the elements of the pharmacokinetic phase of drug activity? Select all that apply.
a) Biotransformation
b) First-pass effect
c) Alterations in cellular environment
d) Half-life
e) Active transport - ANSWER: A, B, D, E
• First-pass effect
• Active transport
• Half-life
• Biotransformation
The nurse is administering Tylenol to a patient with a fever. The patient says that she usually takes
acetaminophen for fever and pain. What should the nurse explain to the patient about the name of
the drug?
a) "The name 'Tylenol' is the trade name for acetaminophen."
b) "Tylenol and acetaminophen are not the same medication."
c) "The name 'Tylenol' is a generic name and is the same as acetaminophen."
d) "The name 'Tylenol' is the chemical name for acetaminophen." - ANSWER: A
The patient is complaining of a headache and asks the nurse which over-the-counter medication form
would work the fastest to help reduce the pain. Which medication form will the nurse suggest?
a. A capsule
b. A tablet
c. An enteric-coated tablet
d. A powder - ANSWER: D
A patient has just received a prescription for an entericcoated stool softener. When teaching the
patient, the nurse
, should include which statement?
a "Take the tablet with 2 to 3 ounces of orange juice."
b "Avoid taking all other medications with any entericcoated
tablet."
c "Crush the tablet before swallowing if you have problems
with swallowing."
d "Be sure to swallow the tablet whole without chewing it." - ANSWER: D
If a drug binds with an enzyme and thereby prevents
the enzyme from binding to its normal target cell, it
will produce which effect?
a. Receptor interaction
b. Enzyme affinity
c. Enzyme interaction
d. Nonspecific interaction - ANSWER: C
Which drugs would be affected by the first-pass effect? (Select all that apply.)
a. Morphine given by IV push injection
b. Sublingual nitroglycerin tablets
c. Diphenhydramine (Benadryl) elixir
d. Levothyroxine (Synthroid) tablets
e. Transdermal nicotine patches
f. Esomeprazole (Nexium) capsules
g. Penicillin given by IV piggyback infusion - ANSWER: C, D, F
When reviewing the mechanism of action of a specific drug, the nurse reads that the drug works by
selective enzyme interaction. This process occurs when the drug
a. alters cell membrane permeability.
b. enhances its effectiveness within the cell walls of the target tissue.
c. is attracted to a receptor on the cell wall, preventing an enzyme from binding to that receptor.
d. binds to an enzyme molecule and inhibits or enhances the enzyme's action with the normal target
cell. - ANSWER: D
When reviewing pharmacology terms for a group of newly graduated nurses, the nurse explains that a
drug's half-life is the time it takes for
a. the drug to cause half of its therapeutic response.
b. one half of the original amount of a drug to reach the target cells.
c. one half of the original amount of a drug to be removed from the body.
d. one half of the original amount of a drug to be absorbed into the circulation. - ANSWER: C
When given an intravenous medication, the patient says to the nurse, "I usually take pills. Why does
this medication have to be given in the arm?" What is the nurse's best answer?
a. "The medication will cause fewer adverse effects when given intravenously."
b. "The intravenous medication will have delayed absorption into the body's tissues."
c. "The action of the medication will begin sooner when given intravenously."
d. "There is a lower chance of allergic reactions when drugs are given intravenously." - ANSWER: C
The nurse recognizes that drugs given by which
route will be altered by the first-pass effect? (Select
all that apply.)
a. Oral
b. Sublingual
c. Subcutaneous
d. Intravenous
e. Rectal - ANSWER: A, E
A drug has a half-life of 4 hours. If at 0800 the drug
Edition By Linda Lilley, Shelly Collins, Julie Snyder Chapter 1-58
| 9780323827973 | All Chapters with Answers and Rationals
Ch 2
A nurse is administering a drug to clients who have the disease for which a drug is designed to treat.
The nurse is most likely participating in which of the following?
a) Phase III study
b) Phase I study
c) Phase II study
d) Preclinical trial - ANSWER: C
Number the following drug forms in order of speed
of dissolution and absorption, with (1) being the fastest
and (5) being the slowest:
_____ a. Capsules
_____ b. Enteric-coated tablets
_____ c. Elixirs
_____ d. Powders
_____ e. Orally disintegrating tablets - ANSWER: E, C, D, A, B
What are the elements of the pharmacokinetic phase of drug activity? Select all that apply.
a) Biotransformation
b) First-pass effect
c) Alterations in cellular environment
d) Half-life
e) Active transport - ANSWER: A, B, D, E
• First-pass effect
• Active transport
• Half-life
• Biotransformation
The nurse is administering Tylenol to a patient with a fever. The patient says that she usually takes
acetaminophen for fever and pain. What should the nurse explain to the patient about the name of
the drug?
a) "The name 'Tylenol' is the trade name for acetaminophen."
b) "Tylenol and acetaminophen are not the same medication."
c) "The name 'Tylenol' is a generic name and is the same as acetaminophen."
d) "The name 'Tylenol' is the chemical name for acetaminophen." - ANSWER: A
The patient is complaining of a headache and asks the nurse which over-the-counter medication form
would work the fastest to help reduce the pain. Which medication form will the nurse suggest?
a. A capsule
b. A tablet
c. An enteric-coated tablet
d. A powder - ANSWER: D
A patient has just received a prescription for an entericcoated stool softener. When teaching the
patient, the nurse
, should include which statement?
a "Take the tablet with 2 to 3 ounces of orange juice."
b "Avoid taking all other medications with any entericcoated
tablet."
c "Crush the tablet before swallowing if you have problems
with swallowing."
d "Be sure to swallow the tablet whole without chewing it." - ANSWER: D
If a drug binds with an enzyme and thereby prevents
the enzyme from binding to its normal target cell, it
will produce which effect?
a. Receptor interaction
b. Enzyme affinity
c. Enzyme interaction
d. Nonspecific interaction - ANSWER: C
Which drugs would be affected by the first-pass effect? (Select all that apply.)
a. Morphine given by IV push injection
b. Sublingual nitroglycerin tablets
c. Diphenhydramine (Benadryl) elixir
d. Levothyroxine (Synthroid) tablets
e. Transdermal nicotine patches
f. Esomeprazole (Nexium) capsules
g. Penicillin given by IV piggyback infusion - ANSWER: C, D, F
When reviewing the mechanism of action of a specific drug, the nurse reads that the drug works by
selective enzyme interaction. This process occurs when the drug
a. alters cell membrane permeability.
b. enhances its effectiveness within the cell walls of the target tissue.
c. is attracted to a receptor on the cell wall, preventing an enzyme from binding to that receptor.
d. binds to an enzyme molecule and inhibits or enhances the enzyme's action with the normal target
cell. - ANSWER: D
When reviewing pharmacology terms for a group of newly graduated nurses, the nurse explains that a
drug's half-life is the time it takes for
a. the drug to cause half of its therapeutic response.
b. one half of the original amount of a drug to reach the target cells.
c. one half of the original amount of a drug to be removed from the body.
d. one half of the original amount of a drug to be absorbed into the circulation. - ANSWER: C
When given an intravenous medication, the patient says to the nurse, "I usually take pills. Why does
this medication have to be given in the arm?" What is the nurse's best answer?
a. "The medication will cause fewer adverse effects when given intravenously."
b. "The intravenous medication will have delayed absorption into the body's tissues."
c. "The action of the medication will begin sooner when given intravenously."
d. "There is a lower chance of allergic reactions when drugs are given intravenously." - ANSWER: C
The nurse recognizes that drugs given by which
route will be altered by the first-pass effect? (Select
all that apply.)
a. Oral
b. Sublingual
c. Subcutaneous
d. Intravenous
e. Rectal - ANSWER: A, E
A drug has a half-life of 4 hours. If at 0800 the drug
