Biochem Exam Questions
O-linked oligosaccharides are commonly attached to the oxygen of... - ANSWER:
threonine
Bacterial cell walls are constructed of - ANSWER: peptidoglycans
Unlike proteins and oligonucleotides, polysaccharides... - ANSWER: often have
branched structures
The process by which nutrients are degraded in order to salvage their components
and/or to generate energy is most specifically called: - ANSWER: catabolism
Glucose can be synthesized from noncarbohydrate precursors by - ANSWER:
gluconeogenesis
In glycogen synthesis, the intermediate between glucose-1-phosphate and glycogen is -
ANSWER: UDP-glucose (or uridine diphosphate glucose)
In skeletal muscle cells, the NADH that is produced by glycolysis under anaerobic
conditions (vigorous exercise) is regenerated to NAD+ by the conversion of: -
ANSWER: pyruvate -- lactate
Which of the following terms describes the citric acid cycle is referred to as being both
catabolic and anabolic? - ANSWER: amphibolic
Which of the following coenzymes is NOT used by the pyruvate dehydrogenase
complex? - ANSWER: pyridoxal phosphate
How many NADH are produced when one acetyl group is oxidized in the citric acid
cycle? - ANSWER: 3
The ubiquitous chemistry of acetyl-CoA is centered on its high-energy ________ bond. -
ANSWER: thioester
Electrons from the cytosol are transferred to the matrix via ___________ systems. -
ANSWER: shuttle
Complexes I and II each transfer electrons to - ANSWER: Coenzyme Q
Which of the following statements are true about oxidative phosphorylation? -
ANSWER: A and B...
A) Electron transport provides energy to pump protons into the inter membrane space
, B) An electrochemical gradient is formed across the inner mitochondrial membrane
How many stereoisomers are possible for a ketohexose? - ANSWER: 8
Which of the following is at a higher level of oxidation than CH3CHO? - ANSWER:
CH3CO2H
The steps in glycolysis that are different than those in gluconeogenesis are catalyzed by
the enzymes: - ANSWER: pyruvate kinase, phosphofructokinase, hexokinase
Which of the following enzymes forms a Schiff base as an intermediate in the
mechanism of its reaction? - ANSWER: A) aldolase
Regulation of which of the following enzymes is important in glycolysis? - ANSWER: A,
B, and C
A) Hexokinase
B) PFK-1
C) Pyruvate Kinase
Patients with von Gierke's disease have a deficiency of glucose-6-phosphatase. One of
the most prominent symptoms of the disease is a protruding abdomen due to an
enlarged liver. What is accumulating in the liver to produce this effect? - ANSWER:
glycogen
Which steps of glycolysis are different from gluconeogenesis? - ANSWER: Steps 1,3,10
__________ is the first compound that is oxidized in the citric acid cycle. - ANSWER:
isocitrate
The regulated enzymes of the citric acid cycle include... - ANSWER: alpha-
Ketoglutarate dehydrogenase
The stoichiometric relationship of ATP synthesis to _________ is referred to as the P/O
ratio. - ANSWER: respiration
The functional core of complex III includes: - ANSWER: cytochrome c1, cytochrome b,
iron-sulfur protein (Rieske protein)
Which statement concerning Complex II of electron transport chain is FALSE? -
ANSWER: This complex includes a cytochrome heme
Which of the following best describes the function of cytochrome c oxidase? -
ANSWER: Cytochrome c oxidase oxidizes four consecutive cytochrome c molecules,
via one-electron transfers, while simultaneously reducing one O2 to two H2O.
O-linked oligosaccharides are commonly attached to the oxygen of... - ANSWER:
threonine
Bacterial cell walls are constructed of - ANSWER: peptidoglycans
Unlike proteins and oligonucleotides, polysaccharides... - ANSWER: often have
branched structures
The process by which nutrients are degraded in order to salvage their components
and/or to generate energy is most specifically called: - ANSWER: catabolism
Glucose can be synthesized from noncarbohydrate precursors by - ANSWER:
gluconeogenesis
In glycogen synthesis, the intermediate between glucose-1-phosphate and glycogen is -
ANSWER: UDP-glucose (or uridine diphosphate glucose)
In skeletal muscle cells, the NADH that is produced by glycolysis under anaerobic
conditions (vigorous exercise) is regenerated to NAD+ by the conversion of: -
ANSWER: pyruvate -- lactate
Which of the following terms describes the citric acid cycle is referred to as being both
catabolic and anabolic? - ANSWER: amphibolic
Which of the following coenzymes is NOT used by the pyruvate dehydrogenase
complex? - ANSWER: pyridoxal phosphate
How many NADH are produced when one acetyl group is oxidized in the citric acid
cycle? - ANSWER: 3
The ubiquitous chemistry of acetyl-CoA is centered on its high-energy ________ bond. -
ANSWER: thioester
Electrons from the cytosol are transferred to the matrix via ___________ systems. -
ANSWER: shuttle
Complexes I and II each transfer electrons to - ANSWER: Coenzyme Q
Which of the following statements are true about oxidative phosphorylation? -
ANSWER: A and B...
A) Electron transport provides energy to pump protons into the inter membrane space
, B) An electrochemical gradient is formed across the inner mitochondrial membrane
How many stereoisomers are possible for a ketohexose? - ANSWER: 8
Which of the following is at a higher level of oxidation than CH3CHO? - ANSWER:
CH3CO2H
The steps in glycolysis that are different than those in gluconeogenesis are catalyzed by
the enzymes: - ANSWER: pyruvate kinase, phosphofructokinase, hexokinase
Which of the following enzymes forms a Schiff base as an intermediate in the
mechanism of its reaction? - ANSWER: A) aldolase
Regulation of which of the following enzymes is important in glycolysis? - ANSWER: A,
B, and C
A) Hexokinase
B) PFK-1
C) Pyruvate Kinase
Patients with von Gierke's disease have a deficiency of glucose-6-phosphatase. One of
the most prominent symptoms of the disease is a protruding abdomen due to an
enlarged liver. What is accumulating in the liver to produce this effect? - ANSWER:
glycogen
Which steps of glycolysis are different from gluconeogenesis? - ANSWER: Steps 1,3,10
__________ is the first compound that is oxidized in the citric acid cycle. - ANSWER:
isocitrate
The regulated enzymes of the citric acid cycle include... - ANSWER: alpha-
Ketoglutarate dehydrogenase
The stoichiometric relationship of ATP synthesis to _________ is referred to as the P/O
ratio. - ANSWER: respiration
The functional core of complex III includes: - ANSWER: cytochrome c1, cytochrome b,
iron-sulfur protein (Rieske protein)
Which statement concerning Complex II of electron transport chain is FALSE? -
ANSWER: This complex includes a cytochrome heme
Which of the following best describes the function of cytochrome c oxidase? -
ANSWER: Cytochrome c oxidase oxidizes four consecutive cytochrome c molecules,
via one-electron transfers, while simultaneously reducing one O2 to two H2O.
