NBME CBSE Form 5 Latest Version/ NBME CBSE Form 5 Actual
Exams and Study Guides/ NBME CBSE Form 4 (2 Versions)
( Questions and Answers)/ NBME CBSE EXAM
Native American women comes to EMD + Her husband died 6 weeks ago + She says
he visits her every night and gives her guidance + Denies suicidal ideation + Neuro and
CT scan of the head show no abnormalities; What is the appropriate next step for the
physician? -------- Correct Answer ---------- Ask her relatives if speaking to deceased
loved ones is common to their culture
The mitogenic signal provided by the PDGF cytokine to smooth muscle cells at sites of
vascular injury is most likely to be INHIBITED by what? -------- Correct Answer ----------
Phosphatase
23 y/o women seeks genetic counseling because her brother has DMDS + Although she
does not have DMA, her risk for carrying the DMD gene is greater than that of the
general population; Why? -------- Correct Answer ---------- Maternal germline mosaicism
Drug X is 500 mg: administerd 3x daily, Causes pain relief but may develop nausea,
vomiting, diarrhea;
Drug Y is 20 mg: Admin 2x daily, Causes pain relief, No nausea, vomiting;
How would you describe the efficacy of these drugs? -------- Correct Answer ----------
Equal
Sequence specific cleavage of proteins plays a role in what process? -------- Correct
Answer ---------- Initiation of coagulation
1 month old boy w/ hydrocephalus has Toxoplasma gondii; What is the route of infection
most likely for this patient? -------- Correct Answer ---------- Transplacental transmission
What molecules must interact to induce immune cell activation by superantigen toxic
shock syndrome toxin-1 -------- Correct Answer ---------- Class MHC II & T cell receptor
Splicing of primary gene transcripts in eukaryotic cells is most likely to have what effect?
-------- Correct Answer ---------- Increased repertoire of gene products
A person has megaloblastic anemia; What lab finding has the earliest response to
treatment? -------- Correct Answer ---------- Reticulocyte count
The 45srRNA is cleaved into 18S, 5.8S, 28S RNAs in what part of the cell? --------
Correct Answer ---------- Nucleolus
, What reaction is critical in protecting erythrocyte from injury by oxidation products --------
Correct Answer ---------- G6PD catalyzed generation of NADPH
What cellular junction blocks the backflow of glucose from the basal side of the
intestinal epithelium into the lumen of the gut? -------- Correct Answer ---------- Tight
junctions
Pregnant women wants an Amniocentesis but has no abnormality indicating this
procedure; What ethical principles should the physician consider when deciding this
patients request? -------- Correct Answer ---------- Autonomy versus maleficence
Cosackievirus -------- Correct Answer ---------- Picornavirus
ssRNA;
No envelope
1 y/o boy is at the 30th percentile for height and weight + Vocab is 10 words + Recently
began walking; What is the best description of the development of boy? -------- Correct
Answer ---------- Motor - Normal;
Language - Normal
Examination of bronchial mucosa shows ciliated pseudostratified glandular epithelium
w/ interspersed foci of normally maturing stratified squamous overlying an intact
basement membrane; What process explains these findings? -------- Correct Answer
---------- Squamous Metaplasia
Abciximab, Eptifibatide, Tirofiban -------- Correct Answer ---------- Monoclonal antibody
that blocks GpIIb/IIIA receptor function
Itraconazole, Ketoconazole, Fluconazole -------- Correct Answer ---------- Inhibit fungal
ergosterol synthesis by inhibiting C14 lanosterol demethylase (converts lanosterol to
ergosterol);
AE: Gynecomastia, Inhibits CYP450
What is the explanation for the emergence of HIV variants resistant to antiviral drugs?
-------- Correct Answer ---------- HIV reverse transcriptase is error prone
1 month old is immunized with an antigen that produces an IgM response during the
next 2 months; What antigen was most likely given? -------- Correct Answer ----------
Bacterial polysaccharide
Patient presents w/ a Pneumothorax; What is the next appropriate step in
management? -------- Correct Answer ---------- Needle aspiration
After orthorpedic surgery, a 48 y/o woman does not begin breathing spontaneously +
Stimulation of the ulnar nerve shows continued neuromuscular blockade; To speed
Exams and Study Guides/ NBME CBSE Form 4 (2 Versions)
( Questions and Answers)/ NBME CBSE EXAM
Native American women comes to EMD + Her husband died 6 weeks ago + She says
he visits her every night and gives her guidance + Denies suicidal ideation + Neuro and
CT scan of the head show no abnormalities; What is the appropriate next step for the
physician? -------- Correct Answer ---------- Ask her relatives if speaking to deceased
loved ones is common to their culture
The mitogenic signal provided by the PDGF cytokine to smooth muscle cells at sites of
vascular injury is most likely to be INHIBITED by what? -------- Correct Answer ----------
Phosphatase
23 y/o women seeks genetic counseling because her brother has DMDS + Although she
does not have DMA, her risk for carrying the DMD gene is greater than that of the
general population; Why? -------- Correct Answer ---------- Maternal germline mosaicism
Drug X is 500 mg: administerd 3x daily, Causes pain relief but may develop nausea,
vomiting, diarrhea;
Drug Y is 20 mg: Admin 2x daily, Causes pain relief, No nausea, vomiting;
How would you describe the efficacy of these drugs? -------- Correct Answer ----------
Equal
Sequence specific cleavage of proteins plays a role in what process? -------- Correct
Answer ---------- Initiation of coagulation
1 month old boy w/ hydrocephalus has Toxoplasma gondii; What is the route of infection
most likely for this patient? -------- Correct Answer ---------- Transplacental transmission
What molecules must interact to induce immune cell activation by superantigen toxic
shock syndrome toxin-1 -------- Correct Answer ---------- Class MHC II & T cell receptor
Splicing of primary gene transcripts in eukaryotic cells is most likely to have what effect?
-------- Correct Answer ---------- Increased repertoire of gene products
A person has megaloblastic anemia; What lab finding has the earliest response to
treatment? -------- Correct Answer ---------- Reticulocyte count
The 45srRNA is cleaved into 18S, 5.8S, 28S RNAs in what part of the cell? --------
Correct Answer ---------- Nucleolus
, What reaction is critical in protecting erythrocyte from injury by oxidation products --------
Correct Answer ---------- G6PD catalyzed generation of NADPH
What cellular junction blocks the backflow of glucose from the basal side of the
intestinal epithelium into the lumen of the gut? -------- Correct Answer ---------- Tight
junctions
Pregnant women wants an Amniocentesis but has no abnormality indicating this
procedure; What ethical principles should the physician consider when deciding this
patients request? -------- Correct Answer ---------- Autonomy versus maleficence
Cosackievirus -------- Correct Answer ---------- Picornavirus
ssRNA;
No envelope
1 y/o boy is at the 30th percentile for height and weight + Vocab is 10 words + Recently
began walking; What is the best description of the development of boy? -------- Correct
Answer ---------- Motor - Normal;
Language - Normal
Examination of bronchial mucosa shows ciliated pseudostratified glandular epithelium
w/ interspersed foci of normally maturing stratified squamous overlying an intact
basement membrane; What process explains these findings? -------- Correct Answer
---------- Squamous Metaplasia
Abciximab, Eptifibatide, Tirofiban -------- Correct Answer ---------- Monoclonal antibody
that blocks GpIIb/IIIA receptor function
Itraconazole, Ketoconazole, Fluconazole -------- Correct Answer ---------- Inhibit fungal
ergosterol synthesis by inhibiting C14 lanosterol demethylase (converts lanosterol to
ergosterol);
AE: Gynecomastia, Inhibits CYP450
What is the explanation for the emergence of HIV variants resistant to antiviral drugs?
-------- Correct Answer ---------- HIV reverse transcriptase is error prone
1 month old is immunized with an antigen that produces an IgM response during the
next 2 months; What antigen was most likely given? -------- Correct Answer ----------
Bacterial polysaccharide
Patient presents w/ a Pneumothorax; What is the next appropriate step in
management? -------- Correct Answer ---------- Needle aspiration
After orthorpedic surgery, a 48 y/o woman does not begin breathing spontaneously +
Stimulation of the ulnar nerve shows continued neuromuscular blockade; To speed
