Maryville University NURS615 Pharmacology Exam 4( 200+ Quiz and
correct answers
Adverse effects of chronic long-term use of PPI? - correct answersosteoporosis
What is the most common cause of PUD? - correct answersH. pylori followed by
NSAIDS and ASA
How to initially treat PUD and H. pylori? - correct answersTriple Therapy; PPI BID,
Amoxil 1 gm BID (metronidazole if allergic), Clarithromycin 500 mg QD 7-14 days
If initial treatment fails what is the next line of therapy for H. pylori? - correct
answersQuadruple therapy; PPI BID 8-12 weeks, metronidazole, tetracycline, bismuth
subsalicylate x 14 days
How is H. pylori transmitted? - correct answersfecal-oral
How is Carafate given and what does it do? - correct answers30 before meals with no
other meds; binds to lesion to protect from stomach acid
1. What is the Step Down Approach with GERD? - correct answers(GOAL to step down
to lower PPI dose or trans to H2Ra) PPI QD x 8 wks, if not working then BID x 4-8
weeks; after 4 wks lower PPI; if no better in 8 weeks at BID then GI referral
What is the Step Up Approach with GERD - correct answers(Use in pts with mild
disease and sx) lifestyle modifications and OTC antacids followed by H2RA blockers
and PPI's
Once treatment for H. pylori is complete how is pt managed? - correct answerscontinue
a long-term PPI
what is recommended for traveler's' diarrhea? - correct answersBismuth salicylate
(Pepto) with each meal and at bedtime as it binds the exotoxins made by e. coli
What are the monitoring parameters for long-term PPI therapy? - correct answersIron
panel, B12, Calcium
If a patient has GERD and takes TUMS with no symptom relief, how do you STEP-UP
their therapy? - correct answers(step up) by starting H2Ra (blocker)
If a patient takes a PPI once daily, how do you STEP-UP their therapy if they have no
symptom relief? - correct answersPPI BID x 4-12 weeks
How does metoclopramide (Reglan) (prokinetic agent) improve GERD symptoms? -
correct answersIncreases the tone of the lower esophageal sphincter (works on both
serotonin & dopamine receptors)
, Maryville University NURS615 Pharmacology Exam 4( 200+ Quiz and
correct answers
What are important counseling points when administering antacids? - correct
answersMUST BE SEPARATED FROM OTHER MEDS BY 1 HOUR; must be
completely chewed and followed with water. Drink 2-4 ounces of water after taking the
liquid antacid; can cause diarrhea (magnisium) or constipation (aluminum)
How does loperamide (Immodium) treat diarrhea? (MOA) - correct answers(Opioid
receptor agonists) Slows gastric motility and reduces fluid and electrolyte loss from
diarrhea
You have a 3 year old patient with a cough and a URI. What is your first line of
treatment? - correct answersfluids and comfort care
Which anti-asthma agent aggravates pulmonary beta receptors and increasing cyclic
AMP? - correct answersShort acting beta agonists (SABA) like Albuterol
What is the Black box warning with LABA - correct answerswhen used as monotherapy
there is an increased risk of asthma-related deaths; must be used in combo with ICS
MOA/ Primary use of Tiotropium (Spiriva)-mucarinic recptor agonist - correct answersTx
for COPD; Acts on M3 muscarinic receptors on smooth muscle cells and submucosal
glands which leads to reduction in smooth muscle contraction & mucus secretion
producing BRONCHODILATORY EFFECTS
Which antiasthma agents activate pulmonary beta receptors and increase a cyclic AMP
(cAMP)? - correct answersSABA
What special populations should not be prescribed pseudoephedrine or phenylepherine
- correct answersDo not use in children 4 years old or younger; elderly; pts with HTN or
CVD
When prescribing singular for asthma, what is an important counseling point - correct
answersCan cause aggression, anxiety, depression, suicide, night terrors
Contraindications to antihistamines are considered in what patient group? - correct
answersElderly, patients with BPH. & High doses can cause hallucinations
What is the MOA of inhaled corticosteroids when treating asthma? - correct
answersProduces anti-inflammatory effects and should be used as preventative therapy
only. block formation of six different inflammatory mediators
When using oral inhaled corticosteroids for asthma or COPD, what is a potential
adverse effect that patients should be aware of? - correct answersOral candidiasis,
thrush, does not help with acute attacks (rinse with water after use).
correct answers
Adverse effects of chronic long-term use of PPI? - correct answersosteoporosis
What is the most common cause of PUD? - correct answersH. pylori followed by
NSAIDS and ASA
How to initially treat PUD and H. pylori? - correct answersTriple Therapy; PPI BID,
Amoxil 1 gm BID (metronidazole if allergic), Clarithromycin 500 mg QD 7-14 days
If initial treatment fails what is the next line of therapy for H. pylori? - correct
answersQuadruple therapy; PPI BID 8-12 weeks, metronidazole, tetracycline, bismuth
subsalicylate x 14 days
How is H. pylori transmitted? - correct answersfecal-oral
How is Carafate given and what does it do? - correct answers30 before meals with no
other meds; binds to lesion to protect from stomach acid
1. What is the Step Down Approach with GERD? - correct answers(GOAL to step down
to lower PPI dose or trans to H2Ra) PPI QD x 8 wks, if not working then BID x 4-8
weeks; after 4 wks lower PPI; if no better in 8 weeks at BID then GI referral
What is the Step Up Approach with GERD - correct answers(Use in pts with mild
disease and sx) lifestyle modifications and OTC antacids followed by H2RA blockers
and PPI's
Once treatment for H. pylori is complete how is pt managed? - correct answerscontinue
a long-term PPI
what is recommended for traveler's' diarrhea? - correct answersBismuth salicylate
(Pepto) with each meal and at bedtime as it binds the exotoxins made by e. coli
What are the monitoring parameters for long-term PPI therapy? - correct answersIron
panel, B12, Calcium
If a patient has GERD and takes TUMS with no symptom relief, how do you STEP-UP
their therapy? - correct answers(step up) by starting H2Ra (blocker)
If a patient takes a PPI once daily, how do you STEP-UP their therapy if they have no
symptom relief? - correct answersPPI BID x 4-12 weeks
How does metoclopramide (Reglan) (prokinetic agent) improve GERD symptoms? -
correct answersIncreases the tone of the lower esophageal sphincter (works on both
serotonin & dopamine receptors)
, Maryville University NURS615 Pharmacology Exam 4( 200+ Quiz and
correct answers
What are important counseling points when administering antacids? - correct
answersMUST BE SEPARATED FROM OTHER MEDS BY 1 HOUR; must be
completely chewed and followed with water. Drink 2-4 ounces of water after taking the
liquid antacid; can cause diarrhea (magnisium) or constipation (aluminum)
How does loperamide (Immodium) treat diarrhea? (MOA) - correct answers(Opioid
receptor agonists) Slows gastric motility and reduces fluid and electrolyte loss from
diarrhea
You have a 3 year old patient with a cough and a URI. What is your first line of
treatment? - correct answersfluids and comfort care
Which anti-asthma agent aggravates pulmonary beta receptors and increasing cyclic
AMP? - correct answersShort acting beta agonists (SABA) like Albuterol
What is the Black box warning with LABA - correct answerswhen used as monotherapy
there is an increased risk of asthma-related deaths; must be used in combo with ICS
MOA/ Primary use of Tiotropium (Spiriva)-mucarinic recptor agonist - correct answersTx
for COPD; Acts on M3 muscarinic receptors on smooth muscle cells and submucosal
glands which leads to reduction in smooth muscle contraction & mucus secretion
producing BRONCHODILATORY EFFECTS
Which antiasthma agents activate pulmonary beta receptors and increase a cyclic AMP
(cAMP)? - correct answersSABA
What special populations should not be prescribed pseudoephedrine or phenylepherine
- correct answersDo not use in children 4 years old or younger; elderly; pts with HTN or
CVD
When prescribing singular for asthma, what is an important counseling point - correct
answersCan cause aggression, anxiety, depression, suicide, night terrors
Contraindications to antihistamines are considered in what patient group? - correct
answersElderly, patients with BPH. & High doses can cause hallucinations
What is the MOA of inhaled corticosteroids when treating asthma? - correct
answersProduces anti-inflammatory effects and should be used as preventative therapy
only. block formation of six different inflammatory mediators
When using oral inhaled corticosteroids for asthma or COPD, what is a potential
adverse effect that patients should be aware of? - correct answersOral candidiasis,
thrush, does not help with acute attacks (rinse with water after use).
