UNIVERSITY of SCIENCES and TECHNOLOGIES of HANOI
UNIVERSITE CLAUDE BERNARD LYON I
FACULTE DE PHARMACIE - ISPB
MASTER 1
BIOTECHNOLOGY AND PHARMACOLOGY
BASIC MOLECULAR PHARMACOLOGY
BP12
Annals of past exams
(with corrections)
Dr. Roger BESANÇON
2022-2023
,Contents
Mid-term exam, year 2012/2013............................................................................................................................... 4
Corrected mid-term exam, year 2012/2013 .............................................................................................................. 7
Final term exam, year 2012/2013 ............................................................................................................................ 12
Corrected final term exam, year 2012/2013 ........................................................................................................... 14
Mid-term exam, year 2013/2014............................................................................................................................. 18
Corrected mid-term exam, year 2013/2014 ............................................................................................................ 20
Final term exam, year 2013/2014 ............................................................................................................................ 28
Corrected final term exam, year 2013/2014 ........................................................................................................... 31
Retake exam, year 2013/2014 ................................................................................................................................. 37
Corrected retake exam, year 2013/2014 ................................................................................................................. 41
Mid-term exam, year 2014/2015............................................................................................................................. 47
Corrected mid-term exam, year 2014/2015 ............................................................................................................ 50
Final term exam, year 2014/2015 ............................................................................................................................ 54
Corrected final term exam, year 2014/2015 ........................................................................................................... 57
Retake exam, year 2014/2015 ................................................................................................................................. 65
Corrected retake exam, year 2014/2015 ................................................................................................................. 67
Mid-term exam, year 2015/2016............................................................................................................................. 70
Corrected mid-term exam, year 2015/2016 ............................................................................................................ 71
Final-term exam, year 2015/2016 ........................................................................................................................... 77
Corrected final-term exam, year 2015/2016 ........................................................................................................... 81
Mid-term exam, year 2016/2017............................................................................................................................. 86
Corrected mid-term exam, year 2016/2017 ............................................................................................................ 89
Final-term exam, year 2016/2017 ........................................................................................................................... 94
Corrected final-term exam, year 2016/2017 ........................................................................................................... 96
Mid-term exam, year 2017/2018........................................................................................................................... 101
,Corrected mid-term exam, year 2017/2018 .......................................................................................................... 104
Final-term exam, year 2017/2018 ......................................................................................................................... 108
Corrected final-term exam, year 2017/2018 ......................................................................................................... 111
Mid-term exam, year 2018/2019........................................................................................................................... 117
Corrected mid-term exam, year 2018/2019 .......................................................................................................... 119
Final-term exam, year 2018/2019 ......................................................................................................................... 124
Corrected final-term exam, year 2018/2019 ......................................................................................................... 129
Mid-term exam, year 2019/2020........................................................................................................................... 135
Corrected mid-term exam, year 2019/2020 .......................................................................................................... 138
Final-term exam, year 2021/2022 ......................................................................................................................... 143
Corrected final-term exam, year 2021/2022 ......................................................................................................... 145
, Mid-term exam, year 2012/2013
Question 1:
What is a “passive channel” in the context of pharmacology?
Question 2
What are the different classes of passive channels?
Question 3
In order to know the affinity of a radioligand: 3H-San54 for the D1 dopamine receptor (D1-R), we used membranes
of CHO cells transfected with D1-R. A saturation study was realized with increasing concentrations of 3H-San54
(F from 0.1 nmol/L to 100 nmol/L). The specific binding 3H-San54 (B) on D1 receptor was measured after
filtration. The results are presented in the following figure:
What is the name of this representation of the saturation study?
Measure the value of KD for 3H-San54 :
UNIVERSITE CLAUDE BERNARD LYON I
FACULTE DE PHARMACIE - ISPB
MASTER 1
BIOTECHNOLOGY AND PHARMACOLOGY
BASIC MOLECULAR PHARMACOLOGY
BP12
Annals of past exams
(with corrections)
Dr. Roger BESANÇON
2022-2023
,Contents
Mid-term exam, year 2012/2013............................................................................................................................... 4
Corrected mid-term exam, year 2012/2013 .............................................................................................................. 7
Final term exam, year 2012/2013 ............................................................................................................................ 12
Corrected final term exam, year 2012/2013 ........................................................................................................... 14
Mid-term exam, year 2013/2014............................................................................................................................. 18
Corrected mid-term exam, year 2013/2014 ............................................................................................................ 20
Final term exam, year 2013/2014 ............................................................................................................................ 28
Corrected final term exam, year 2013/2014 ........................................................................................................... 31
Retake exam, year 2013/2014 ................................................................................................................................. 37
Corrected retake exam, year 2013/2014 ................................................................................................................. 41
Mid-term exam, year 2014/2015............................................................................................................................. 47
Corrected mid-term exam, year 2014/2015 ............................................................................................................ 50
Final term exam, year 2014/2015 ............................................................................................................................ 54
Corrected final term exam, year 2014/2015 ........................................................................................................... 57
Retake exam, year 2014/2015 ................................................................................................................................. 65
Corrected retake exam, year 2014/2015 ................................................................................................................. 67
Mid-term exam, year 2015/2016............................................................................................................................. 70
Corrected mid-term exam, year 2015/2016 ............................................................................................................ 71
Final-term exam, year 2015/2016 ........................................................................................................................... 77
Corrected final-term exam, year 2015/2016 ........................................................................................................... 81
Mid-term exam, year 2016/2017............................................................................................................................. 86
Corrected mid-term exam, year 2016/2017 ............................................................................................................ 89
Final-term exam, year 2016/2017 ........................................................................................................................... 94
Corrected final-term exam, year 2016/2017 ........................................................................................................... 96
Mid-term exam, year 2017/2018........................................................................................................................... 101
,Corrected mid-term exam, year 2017/2018 .......................................................................................................... 104
Final-term exam, year 2017/2018 ......................................................................................................................... 108
Corrected final-term exam, year 2017/2018 ......................................................................................................... 111
Mid-term exam, year 2018/2019........................................................................................................................... 117
Corrected mid-term exam, year 2018/2019 .......................................................................................................... 119
Final-term exam, year 2018/2019 ......................................................................................................................... 124
Corrected final-term exam, year 2018/2019 ......................................................................................................... 129
Mid-term exam, year 2019/2020........................................................................................................................... 135
Corrected mid-term exam, year 2019/2020 .......................................................................................................... 138
Final-term exam, year 2021/2022 ......................................................................................................................... 143
Corrected final-term exam, year 2021/2022 ......................................................................................................... 145
, Mid-term exam, year 2012/2013
Question 1:
What is a “passive channel” in the context of pharmacology?
Question 2
What are the different classes of passive channels?
Question 3
In order to know the affinity of a radioligand: 3H-San54 for the D1 dopamine receptor (D1-R), we used membranes
of CHO cells transfected with D1-R. A saturation study was realized with increasing concentrations of 3H-San54
(F from 0.1 nmol/L to 100 nmol/L). The specific binding 3H-San54 (B) on D1 receptor was measured after
filtration. The results are presented in the following figure:
What is the name of this representation of the saturation study?
Measure the value of KD for 3H-San54 :
