BSC
BSCZO- 102
B. Sc. I YEAR
CELL & MOLECULAR BIOLOGY
DEPARTMENT OF ZOOLOGY
SCHOOL OF SCIENCES
UTTARAKHAND OPEN UNIVERSITY
, BSCZO-102
Cell and Molecular Biology
DEPARTMENT OF ZOOLOGY
SCHOOL OF SCIENCES
UTTARAKHAND OPEN UNIVERSITY
Phone No. 05946-261122, 261123
Toll free No. 18001804025
Fax No. 05946-264232, E. mail
htpp://uou.ac.in
, Board of Studies and Programme Coordinator
Board of Studies
Prof. B.D.Joshi Prof. H.C.S.Bisht
Retd.Prof. Department of Zoology
Department of Zoology DSB Campus, Kumaun University,
Gurukul Kangri, University Nainital
Haridwar
Prof. H.C.Tiwari
Dr.N.N.Pandey Retd. Prof. & Principal
Senior Scientist, Department of Zoology,
Directorate of Coldwater Fisheries MB Govt.PG College
(ICAR) Haldwani Nainital.
Bhimtal (Nainital).
Dr. Shyam S.Kunjwal
Department of Zoology
School of Sciences, Uttarakhand Open University
Programme Coordinator
Dr. Shyam S.Kunjwal
Department of Zoology
School of Sciences, Uttarakhand Open University
Haldwani, Nainital
Unit writing and Editing
Editor Writer
Dr.(Ms) Meenu Vats Dr.Mamtesh Kumari,
Professor & Head Associate. Professor
Department of Zoology, Department of Zoology
DAV College,Sector-10 Govt. PG College
Chandigarh-160011 Uttarkashi (Uttarakhand)
Dr.Sunil Bhandari
Asstt. Professor.
Department of Zoology
BGR Campus Pauri,
HNB (Central University) Garhwal.
Course Title and Code : Cell and Molecular Biology (BSCZO 102)
ISBN : 978-93-85740-54-1
Copyright : Uttarakhand Open University
Edition : 2017
Published By : Uttarakhand Open University, Haldwani, Nainital- 263139
, Contents
Course 1: Cell and Molecular Biology
Course code: BSCZO102 Credit: 3
Unit Block and Unit title Page
number Number
Block 1 Cell Biology or Cytology 1-128
1 Cell Type: History and origin. Prokaryotic and Eukaryotic cell. Difference 1-16
between Prokaryotic and Eukaryotic cell.
2 Plasma Membrane: History, Ultra structure, and chemical composition of plasma 17-31
membrane (Lamellar-models, micellar models and fluid mosaic model). Functions
of plasma membrane .
3 Mitochondria: History and structure of mitochondria, biogenesis and functions of 32-44
mitochondria (Respiratory chain complex and Electron transport mechanism).
4 Endoplasmic Recticulum, Ribosome, Golgi Bodies: History, structure, functions 45-65
and importance.
5 Lysosomes, Centrioles, Microtubules: History, structure, functions and 66-79
Importance.
6 Nucleus: History, structure, functions and importance. 80-91
7 Chromosomes: History, types and functions of chromosomes. Giant 92-104
chromosomes, Polytene chromosome and Lampbrush chromosome.
8 Cell Division: Mitosis (cell cycle stages, cytokinesis) Meiosis (reproductive cycle 105-128
stages, synoptonemal complex, recombination nodules). Comparison between
meiosis and mitosis.
BLOCK 2 Molecular Biology: 129-204
9 Structure and Type of DNA: Structure, functions and type of DNA, Watson 129-152
And Crick’s structural model of DNA, chemical composition of DNA, replication
of DNA and recombinant DNA.
10 Structure of RNA: Structure of RNA (primary, secondary and tertiary structure) and 153-172
types of RNA (transfer RNA, messenger RNA, ribosomal RNA). Biosynthesis of m-
RNA, t-RNA. Function and importance of RNA.
11 Protein Synthesis and Regulation: Protein Synthesis, mechanism (initiation, 173-194
elongation and termination) of protein synthesis. Gene regulation (Operon hypothesis:
regulator gene, promoter gene, operator gene, structural gene, repressor gene, co-
repressor gene and inducer gene), regulation at transcription, regulation by gene
arrangement and reversible phosphorylation, types of control mechanisms, regulation of
gene activity in eukaryotes.
12 Genetic Code: Properties of genetic code, codons and anti codon, The Wobble 195-204
Hypothesis, Mutation and the triplet code.
BSCZO- 102
B. Sc. I YEAR
CELL & MOLECULAR BIOLOGY
DEPARTMENT OF ZOOLOGY
SCHOOL OF SCIENCES
UTTARAKHAND OPEN UNIVERSITY
, BSCZO-102
Cell and Molecular Biology
DEPARTMENT OF ZOOLOGY
SCHOOL OF SCIENCES
UTTARAKHAND OPEN UNIVERSITY
Phone No. 05946-261122, 261123
Toll free No. 18001804025
Fax No. 05946-264232, E. mail
htpp://uou.ac.in
, Board of Studies and Programme Coordinator
Board of Studies
Prof. B.D.Joshi Prof. H.C.S.Bisht
Retd.Prof. Department of Zoology
Department of Zoology DSB Campus, Kumaun University,
Gurukul Kangri, University Nainital
Haridwar
Prof. H.C.Tiwari
Dr.N.N.Pandey Retd. Prof. & Principal
Senior Scientist, Department of Zoology,
Directorate of Coldwater Fisheries MB Govt.PG College
(ICAR) Haldwani Nainital.
Bhimtal (Nainital).
Dr. Shyam S.Kunjwal
Department of Zoology
School of Sciences, Uttarakhand Open University
Programme Coordinator
Dr. Shyam S.Kunjwal
Department of Zoology
School of Sciences, Uttarakhand Open University
Haldwani, Nainital
Unit writing and Editing
Editor Writer
Dr.(Ms) Meenu Vats Dr.Mamtesh Kumari,
Professor & Head Associate. Professor
Department of Zoology, Department of Zoology
DAV College,Sector-10 Govt. PG College
Chandigarh-160011 Uttarkashi (Uttarakhand)
Dr.Sunil Bhandari
Asstt. Professor.
Department of Zoology
BGR Campus Pauri,
HNB (Central University) Garhwal.
Course Title and Code : Cell and Molecular Biology (BSCZO 102)
ISBN : 978-93-85740-54-1
Copyright : Uttarakhand Open University
Edition : 2017
Published By : Uttarakhand Open University, Haldwani, Nainital- 263139
, Contents
Course 1: Cell and Molecular Biology
Course code: BSCZO102 Credit: 3
Unit Block and Unit title Page
number Number
Block 1 Cell Biology or Cytology 1-128
1 Cell Type: History and origin. Prokaryotic and Eukaryotic cell. Difference 1-16
between Prokaryotic and Eukaryotic cell.
2 Plasma Membrane: History, Ultra structure, and chemical composition of plasma 17-31
membrane (Lamellar-models, micellar models and fluid mosaic model). Functions
of plasma membrane .
3 Mitochondria: History and structure of mitochondria, biogenesis and functions of 32-44
mitochondria (Respiratory chain complex and Electron transport mechanism).
4 Endoplasmic Recticulum, Ribosome, Golgi Bodies: History, structure, functions 45-65
and importance.
5 Lysosomes, Centrioles, Microtubules: History, structure, functions and 66-79
Importance.
6 Nucleus: History, structure, functions and importance. 80-91
7 Chromosomes: History, types and functions of chromosomes. Giant 92-104
chromosomes, Polytene chromosome and Lampbrush chromosome.
8 Cell Division: Mitosis (cell cycle stages, cytokinesis) Meiosis (reproductive cycle 105-128
stages, synoptonemal complex, recombination nodules). Comparison between
meiosis and mitosis.
BLOCK 2 Molecular Biology: 129-204
9 Structure and Type of DNA: Structure, functions and type of DNA, Watson 129-152
And Crick’s structural model of DNA, chemical composition of DNA, replication
of DNA and recombinant DNA.
10 Structure of RNA: Structure of RNA (primary, secondary and tertiary structure) and 153-172
types of RNA (transfer RNA, messenger RNA, ribosomal RNA). Biosynthesis of m-
RNA, t-RNA. Function and importance of RNA.
11 Protein Synthesis and Regulation: Protein Synthesis, mechanism (initiation, 173-194
elongation and termination) of protein synthesis. Gene regulation (Operon hypothesis:
regulator gene, promoter gene, operator gene, structural gene, repressor gene, co-
repressor gene and inducer gene), regulation at transcription, regulation by gene
arrangement and reversible phosphorylation, types of control mechanisms, regulation of
gene activity in eukaryotes.
12 Genetic Code: Properties of genetic code, codons and anti codon, The Wobble 195-204
Hypothesis, Mutation and the triplet code.
