Advanced Pharmacology
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Advanced Pharmacology test-bank. Latest 2024-
2025
1. A patient has been prescribed an oral drug that is known to have a high first-pass
effect. Which of the following measures has the potential to increase the amount
of the free drug that is available to body cells?
A) Giving the drug with food in order to delay absorption
B) Administering the drug in small, frequent doses
C) Limiting the patient's protein intake and encouraging fluids
D) Administering the drug intravenously rather than orally: D) Administering the
drug intravenously rather than orally
2. A nurse is developing a care plan for a patient who has multiple sclerosis. An
expected outcome for the patient who is receiving glatiramer would be a decrease in
A) chest pain.
B) fatigue.
C) breathing difficulties.
D) heart palpitations: B) fatigue.
3. An elderly postsurgical patient has developed postoperative pneumonia in the
days following abdominal surgery and is being treated with a number of
medications. Which of the following medications that the nurse will administer has
the slowest absorption?
A) A sublingual benzodiazepine that has been prescribed to help the patient sleep
B) An intravenous (IV) antibiotic that is being administered by IV piggyback at
150 mL/hour
C) An oral antidepressant that the patient has been taking daily for several years
D) An intramuscular (IM) injection of an opioid analgesic: C) An oral
antidepressant that the patient has been taking daily for several years
4. A female patient diagnosed with chronic atrial flutter has been prescribed
verapamil in conjunction with digoxin to control ventricular rate. To enhance the
therapeutic effect of the drug, the nurse will instruct the patient to__
A) take the medication with meals.
, Advanced Pharmacology
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B) avoid grapefruit and grapefruit juice.
C) take an aspirin every day.
D) avoid fresh fruit: B) Avoid grapefruit and grapefruit juice.
However, grapefruit juice or the grapefruit itself interacts with antiarrhythmic drugs like
verapamil and digoxin. The nurse should then instruct the client to avoid taking any
grapefruit products as they may cause problems [2]. Grapefruits and grapefruit juice
decrease the absorption rate of certain drugs or letting the drug stay longer in the blood. If
the patient's prescribed drugs are taken with any grapefruit product, the medications
would stay longer in the bloodstream, increasing the client's risk for liver and muscle
damage which could later lead to kidney failure [2].
5. A 28-year-old patient asks his nurse how phenelzine therapy would help him. An
appropriate response by the nurse would be__
A) "This therapy will help reduce the severity of your bipolar episodes."
B) "The drug will enable you to gain the appropriate weight."
C) "The drug will help increase your attention level."
D) "This therapy will improve your overall mood and increase your social activity:
D) "This therapy will improve your overall mood and increase your social activity
6. A nurse is creating a plan of care for a 68-year-old woman with a recent diagnosis
of unstable angina and new prescription for nitroglycerin. Which of the following
nursing diagnoses should the nurse prioritize in the planning of this patient's care?
A) Incontinence, Functional, related to adverse effects of drug therapy
B) Risk for Fluid Volume Deficit related to adverse effects of drug therapy
C) Confusion, Acute, related to adverse effects of drug therapy
D) Acute Pain, Headache, related to adverse effects of drug therapy: D) Acute
Pain, Headache, related to adverse effects of drug therapy
7. A nurse is caring for a 38-year-old female patient who just started taking lithium
for bipolar disorder. Which of the following outcomes would be most appropriate
for this patient?
A) The patient will reestablish and maintain a normal pattern of bowel func-
tioning.
B) The patient will identify appropriate interventions to promote sleep.
C) The patient will identify satisfying and acceptable sexual practices and some
alternative ways of dealing with sexual expression.
, Advanced Pharmacology
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D) The patient will adopt strategies to maintain proper fluid balance: D) The patient
will adopt strategies to maintain proper fluid balance
8. A nurse is caring for a patient who is taking sodium polystyrene sulfonate
(Kayexalate) therapy. The nurse will monitor for which of the following?
A) Cardiac arrhythmias
B) Ventricular arrhythmias
C) Hypokalemia
D) Cardiotoxicity: C) Hypokalemia
9. A nurse is the cardiac care unit is preparing to hang an intravenous dose of
dofetilide (Tikosyn) for a patient who has just been admitted. What is the most
likely goal of this intervention?
A) To treat sinus bradycardia accompanied by hypotension
B) To resolve the patient's uncompensated heart failure
C) To treat the patient's ventricular tachycardia
D) To convert the patient's atrial fibrillation to normal sinus rhythm: D) To convert
the patient's atrial fibrillation to normal sinus rhythm
10. A nurse is working in a women's hospital where she is caring for a new mother
who is experiencing postpartum urinary retention. Bethanechol (Urecholine) has
been ordered. The nurse will observe for which of the following?
A) Bradycardia
B) Hypertension
C) Hypotension
D) Decreased salivation: B) Hypertension
Hypertension is defined as the condition of high blood pressure in the body of an
individual. This can occur as a result of retention of enormous amount of urine in the
body. As such, the person is likely to display symptoms such as leg swellings and
damaging of the kidney affecting its efficiency. Urinary retention is because of some kind
of blockage in the urinary tract. Thus this condition can medically be dealt with by the
application of Bethanechol which aids in easing the urination process which is affected
by the processes of birth, surgery and other medical processes and prescriptions.
11. A 12-year-old child who has been taking sertraline for the past 2 weeks has
returned to the clinic to be seen. It will be critical for the nurse to assess for
A) onset of suicidal ideation.
, Advanced Pharmacology
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B) weight loss.
C) feelings of grandiosity.
D) decreased sleep: A) onset of suicidal ideation.
Sertraline is an antidepressant medication commonly used to treat depression, anxiety
disorders, and other mental health conditions. While it is generally safe and effective, it
can increase the risk of suicidal thoughts and behavior, especially in children and
adolescents. Therefore, the nurse should monitor the child for any signs of suicidal
ideation, such as talking about death or self-harm, withdrawing from social activities, or
showing sudden changes in mood or behavior.
12. A 30-year-old woman is taking phenelzine (Nardil) 30mg PO tid. The nurse
knows that at that dosage, the patient will need to be carefully monitored for
A) dizziness.
B) diarrhea.
C) increased secretions.
D) facial flushing.: A) dizziness.
13. A patient has been admitted to the intensive care unit following a myocardial
infarction. His nurse is preparing to administer his ordered medications when she
notices that one drug ordered is used for treating seizure disorders. The nurse does
not find a history of seizures in the patient's record. The most appropriate action for
the nurse is to__
A) ask the charge nurse if she knows why the drug has been ordered.
B) look up the drug to see if there are other conditions that the drug could be
prescribed for.
C) question the physician about the prescribed medication.
D) call the pharmacist and inquire about therapeutic uses of the drug.: C) question
the physician about the prescribed medication.
14. A nurse is aware of the high incidence and prevalence of major depression in the
population. Which of the following individuals possesses the clearest risk factors for
depression?
A) A man who has a history of intravenous drug use and multiple hospital
admissions for subsequent infections
B) A woman whose father had a long history of depression before he commit-ted
suicide
C) A man who is experiencing significant lifestyle changes after losing his job
Study online at https://quizlet.com/_dfscpq
Advanced Pharmacology test-bank. Latest 2024-
2025
1. A patient has been prescribed an oral drug that is known to have a high first-pass
effect. Which of the following measures has the potential to increase the amount
of the free drug that is available to body cells?
A) Giving the drug with food in order to delay absorption
B) Administering the drug in small, frequent doses
C) Limiting the patient's protein intake and encouraging fluids
D) Administering the drug intravenously rather than orally: D) Administering the
drug intravenously rather than orally
2. A nurse is developing a care plan for a patient who has multiple sclerosis. An
expected outcome for the patient who is receiving glatiramer would be a decrease in
A) chest pain.
B) fatigue.
C) breathing difficulties.
D) heart palpitations: B) fatigue.
3. An elderly postsurgical patient has developed postoperative pneumonia in the
days following abdominal surgery and is being treated with a number of
medications. Which of the following medications that the nurse will administer has
the slowest absorption?
A) A sublingual benzodiazepine that has been prescribed to help the patient sleep
B) An intravenous (IV) antibiotic that is being administered by IV piggyback at
150 mL/hour
C) An oral antidepressant that the patient has been taking daily for several years
D) An intramuscular (IM) injection of an opioid analgesic: C) An oral
antidepressant that the patient has been taking daily for several years
4. A female patient diagnosed with chronic atrial flutter has been prescribed
verapamil in conjunction with digoxin to control ventricular rate. To enhance the
therapeutic effect of the drug, the nurse will instruct the patient to__
A) take the medication with meals.
, Advanced Pharmacology
Study online at https://quizlet.com/_dfscpq
B) avoid grapefruit and grapefruit juice.
C) take an aspirin every day.
D) avoid fresh fruit: B) Avoid grapefruit and grapefruit juice.
However, grapefruit juice or the grapefruit itself interacts with antiarrhythmic drugs like
verapamil and digoxin. The nurse should then instruct the client to avoid taking any
grapefruit products as they may cause problems [2]. Grapefruits and grapefruit juice
decrease the absorption rate of certain drugs or letting the drug stay longer in the blood. If
the patient's prescribed drugs are taken with any grapefruit product, the medications
would stay longer in the bloodstream, increasing the client's risk for liver and muscle
damage which could later lead to kidney failure [2].
5. A 28-year-old patient asks his nurse how phenelzine therapy would help him. An
appropriate response by the nurse would be__
A) "This therapy will help reduce the severity of your bipolar episodes."
B) "The drug will enable you to gain the appropriate weight."
C) "The drug will help increase your attention level."
D) "This therapy will improve your overall mood and increase your social activity:
D) "This therapy will improve your overall mood and increase your social activity
6. A nurse is creating a plan of care for a 68-year-old woman with a recent diagnosis
of unstable angina and new prescription for nitroglycerin. Which of the following
nursing diagnoses should the nurse prioritize in the planning of this patient's care?
A) Incontinence, Functional, related to adverse effects of drug therapy
B) Risk for Fluid Volume Deficit related to adverse effects of drug therapy
C) Confusion, Acute, related to adverse effects of drug therapy
D) Acute Pain, Headache, related to adverse effects of drug therapy: D) Acute
Pain, Headache, related to adverse effects of drug therapy
7. A nurse is caring for a 38-year-old female patient who just started taking lithium
for bipolar disorder. Which of the following outcomes would be most appropriate
for this patient?
A) The patient will reestablish and maintain a normal pattern of bowel func-
tioning.
B) The patient will identify appropriate interventions to promote sleep.
C) The patient will identify satisfying and acceptable sexual practices and some
alternative ways of dealing with sexual expression.
, Advanced Pharmacology
Study online at https://quizlet.com/_dfscpq
D) The patient will adopt strategies to maintain proper fluid balance: D) The patient
will adopt strategies to maintain proper fluid balance
8. A nurse is caring for a patient who is taking sodium polystyrene sulfonate
(Kayexalate) therapy. The nurse will monitor for which of the following?
A) Cardiac arrhythmias
B) Ventricular arrhythmias
C) Hypokalemia
D) Cardiotoxicity: C) Hypokalemia
9. A nurse is the cardiac care unit is preparing to hang an intravenous dose of
dofetilide (Tikosyn) for a patient who has just been admitted. What is the most
likely goal of this intervention?
A) To treat sinus bradycardia accompanied by hypotension
B) To resolve the patient's uncompensated heart failure
C) To treat the patient's ventricular tachycardia
D) To convert the patient's atrial fibrillation to normal sinus rhythm: D) To convert
the patient's atrial fibrillation to normal sinus rhythm
10. A nurse is working in a women's hospital where she is caring for a new mother
who is experiencing postpartum urinary retention. Bethanechol (Urecholine) has
been ordered. The nurse will observe for which of the following?
A) Bradycardia
B) Hypertension
C) Hypotension
D) Decreased salivation: B) Hypertension
Hypertension is defined as the condition of high blood pressure in the body of an
individual. This can occur as a result of retention of enormous amount of urine in the
body. As such, the person is likely to display symptoms such as leg swellings and
damaging of the kidney affecting its efficiency. Urinary retention is because of some kind
of blockage in the urinary tract. Thus this condition can medically be dealt with by the
application of Bethanechol which aids in easing the urination process which is affected
by the processes of birth, surgery and other medical processes and prescriptions.
11. A 12-year-old child who has been taking sertraline for the past 2 weeks has
returned to the clinic to be seen. It will be critical for the nurse to assess for
A) onset of suicidal ideation.
, Advanced Pharmacology
Study online at https://quizlet.com/_dfscpq
B) weight loss.
C) feelings of grandiosity.
D) decreased sleep: A) onset of suicidal ideation.
Sertraline is an antidepressant medication commonly used to treat depression, anxiety
disorders, and other mental health conditions. While it is generally safe and effective, it
can increase the risk of suicidal thoughts and behavior, especially in children and
adolescents. Therefore, the nurse should monitor the child for any signs of suicidal
ideation, such as talking about death or self-harm, withdrawing from social activities, or
showing sudden changes in mood or behavior.
12. A 30-year-old woman is taking phenelzine (Nardil) 30mg PO tid. The nurse
knows that at that dosage, the patient will need to be carefully monitored for
A) dizziness.
B) diarrhea.
C) increased secretions.
D) facial flushing.: A) dizziness.
13. A patient has been admitted to the intensive care unit following a myocardial
infarction. His nurse is preparing to administer his ordered medications when she
notices that one drug ordered is used for treating seizure disorders. The nurse does
not find a history of seizures in the patient's record. The most appropriate action for
the nurse is to__
A) ask the charge nurse if she knows why the drug has been ordered.
B) look up the drug to see if there are other conditions that the drug could be
prescribed for.
C) question the physician about the prescribed medication.
D) call the pharmacist and inquire about therapeutic uses of the drug.: C) question
the physician about the prescribed medication.
14. A nurse is aware of the high incidence and prevalence of major depression in the
population. Which of the following individuals possesses the clearest risk factors for
depression?
A) A man who has a history of intravenous drug use and multiple hospital
admissions for subsequent infections
B) A woman whose father had a long history of depression before he commit-ted
suicide
C) A man who is experiencing significant lifestyle changes after losing his job
