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Rasmussen Pathophysiology Exam 1 . Latest 2025-
2025
1. · Excess of fluid in interstitial compartment; may be localized or generalized;
stages +1, +2, +3, +4: Causes of Edema
2. Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and plasma
viscosity (PV) blood tests are commonly used to detect an increase in protein in
the blood.: Lab tests with inflammation
3. · Maintaining internal conditions in a stable state by keeping things relatively the
same, or balanced.: Homeostasis
4. Overall weight loss and generalized weakness that may have resulted from toxins
released by cancer cells. Loss of appetite, nausea, vomiting. Increased metabolic
rate.: Cachexia
5. Extremely malignant bone forming tumor in adolescent and young adults.
Develop in a metaphysical region of long bones. May cause limb pain,
compromised joint function.: Osteosarcoma
6. DVT, Pulmonary embolism: Complication of bone fracture
7. Muscle loss, infection, nerve damage, amputation, and possible kidney damage.:
Complication of compartment syndrome
8. · Thirst, decreased urine output, hypotension: Signs of dehydration
9. · Fight or flight response. The purpose is to restore balance. It provides a surge of
energy and physical alterations to either evade or confront danger.-
: Alarm phase of Han Seley's General adaptation syndrome
10. · A disorder characterized by widespread musculoskeletal pain accompanied
by fatigue, sleep, memory and mood issues.: Fibromyalgia
11. · Enhanced myocardial contractility, increased heart rate, bronchodilation,
and elevated blood glucose levels.: Flight or fight response signs and symptoms
12. 12. · Elevated uric acid and disturbance in uric acid metabolism.: Causes of
Gout
13. · Vasodilator that reduces BP, causes bronchoconstriction and mucus
production. Treats hives, pruritus and swelling.: Action of Histamine
14. Cortisol and catecholamines.: Stress hormones/hormones secreted during body's
stress response
15. · Redness, pain, swelling, heat, loss of function.: Cardinal signs of inflammation
16. Cancer cells escape their tissue of origin and initiate new colonies of cancer in
distant sites. They escape basement membranes, travel through extracellular space,
and penetrate in the basement membrane.: Metastasis
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17. 17. · progressive loss of muscle tissues. A group of diseases that cause
progressive weakness and loss of muscle mass. Abnormal genes (mutations)
interfere with the production of proteins needed to form healthy muscle.
Person usually gets progressively weaker and will most people eventually need to
use a wheelchair; lifespan is often shortened.: Muscular dystrophy
18. · Most common type of arthritis; occurs when the protective cartilage that
cushions the ends of your bones wears down over time. Can damage any joint,
but most commonly affects joints in your hands, knees, hips and spine.:
Osteoarthritis
19. Most common metabolic bone disease in which reduction in bone mass results
from bone resorption proceeding at a rate faster than that of new bone
formation.: Osteoporosis
20. · Etiology: study of causes. Pathogenesis: Development/evolution of disease.
Clinical manifestations: signs/syndromes/symptoms. Treatment implications.:
Components of Pathophysiology
21. study of causes.: Etiology
22. Development/evolution of disease.: Pathogenesis
23. signs/syndromes/symptoms: Clinical manifestations
24. · An autoimmune inflammatory disease. Systemic autoimmune inflammatory
disease; inflammatory response in rheumatoid joint leads to accumulation of
immune cells and infiltration of the synovium; granulation tissue forms over
articular cartilage; leads to pannus formation; pannus can erode and destroy
articular cartilage, resulting in bone erosion, bone cysts, and fissures.:
Rheumatoid arthritis
25. · Inflammatory arthritis associated with psoriasis, peak age 30-55 years old.:
Psoriatic arthritis
26. May be divided into at least three stages: initiation, promotion, and
progression.: Steps of carcinogenesis
27. · Pain, paralysis, paresthesia, pallor, and pulselessness.: Five p's of compartment
syndrome
28. Pain, burning, numbness, or tingling; sensitivity to touch, red rash that begins a
few days after the pain starts, itching, fluid-filled blisters that break open and
crust over.: Manifestations of Shingles
29. Powerhouse of the cell. Converts energy to forms that can be used to drive
cellular reactions. Also has an important role in programmed cell death, called
apoptosis.: Functions of Mitochondria
30. The ability to successfully adapt to changes, orchestrated by the brain,
maintains and reestablishes homeostasis.: Allostasis
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