Test Bank For Modern Blood Banking & Transfusion Practices
7th Edition By Denise M Harmening 9780803668881 Chapter
1-29 Complete Guide .
How would the hematocrit of a patient with chronic anemia be affected by the transfusion of a unit of
Whole Blood containing 475 mL of blood, vs 2 units of Red Blood Cells each with a total volume of 250
mL?
a. patient's hematocrit would be equally affected by the Whole Blood or the Red Blood cells
b. Red blood cells would provide twice the increment in hematocrit as the whole blood
c. whole blood would provide twice the increment in hematocrit as the red blood cells
d. whole blood would provide a change in hematocrit slightly less than the red blood cells - ANSWER:
b
Each unit of whole blood or rbcs will increase the hematocrit 3%-5%, so 2 units of rbcs will increase
the hematocrit by twice as must as 1 unit of whole blood
After checking the inventory, it was noted that there were no units on the shelf marked "May issue as
Uncrossmatched: For Emergency Only". Which of the following should be placed on this shelf?
a. 1 unit of each of the ABO blood groups
b. units of group O, Rh-positive whole blood
c. units of group O, Rh-negative red blood cells
d. any units that are expiring at midnight - ANSWER: c
For emergency transfusions, group O-rbc units should be used.
The primary indication for granulocyte transfusion is:
a. prophylactic treatment for infection
b. additional supportive therapy in those patients who are responsive to antibiotic therapy
c. clinical situations where bone marrow recovery is not anticipated
d. severe neutropenia with an infection that is nonresponsive to antibiotic therapy - ANSWER: d
Granulocyte transfusions may be indicated for severely neutropenic patients with infection not
controlled by antibiotic therapy, who are expected to recover bone marrow production of white cells.
A 42 yr old male of average body mass has a history of chronic anemia requiring transfusion support.
Two units of red blood cells are transfused. If the pretransfusion hemoglobin was 7.0 g/dl (70g/L), the
expected posttransfusion hemoglobin concentration should be:
a. 8.0 g/dl (80g/L)
b. 9.0 g/dl (90g/L)
c. 10.0 g/dl (100 g/L)
d. 11.0 g/dl (110 g/L) - ANSWER: b
Each unit of rbcs is expected to increase the hemoglobin level by 1-1.5 g/dl (10-15 g/L).
How many units of red blood cells are required to raise the hematocrit of a 70 kg nonbleeding man
from 24% to 30%?
a. 1
b. 2
c. 3
d. 4 - ANSWER: b
, Each unit of rbcs is expected to increase the hematocrit level 3%-5%, so it would take 2 units to raise
the level 6%.
For which of the following transfusion candidates would CMV-seronegative blood be most likely
indicated?
a. renal dialysis patients
b. sickle cell patient
c. bone marrow and hematopoietic cell transplant recipients
d. CMV-seropositive patients - ANSWER: c
CMV-seronegative or leukoreduced blood products should be administered to immunocompromised
patients, including bone marrow and hematopoietic cell transplant recipients.
Although ABO compatibility is preferred, ABO incompatible product may be administered when
transfusing:
a. Single-Donor Plasma
b. Cryoprecipitated AHF
c. FFP
d. Granulocytes - ANSWER: b
Cryoprecipitate contains ABO antibodies so one should consider giving ABO compatible, especially
when infusing large volumes.
Transfusion of plateletpheresis products from HLA-compatible donors is the preferred treatment:
a. recently diagnosed cases of TTP with severe thrombocytopenia
b. acute leukemia in relapse with neutropenia, thrombocytopenia and sepsis
c. immune thrombocytopenic purpura
d. severely thrombocytopenic patients, known to be refractory to random donor platelets - ANSWER:
d
Class I HLA antigens on platelets are a known cause for platelet refractoriness. Leukoreduction of
blood products is used as a mechanism to reduce or prevent patients from developing antibodies.
Washed red blood cells are indicated in which of the following situations?
a. an IgA-deficient patient with a history of transfusion-associated anaphylaxis
b. a pregnant woman with a history of hemolytic disease of the newborn
c. a patient with a positive DAT and red cell autoantibody
d. a newborn with a hematocrit of <30% - ANSWER: a
Patients with IgA deficiency who have had anaphylactic transfusion reactions should receive washed
rbcs. Anaphylactic reactions are typically caused by anti-IgA in the recipient. Washing removes plasma
IgA from the donor unit cells
Which of the following is consistent with standard blood bank procedure governing the infusion of
FFP?
a. only blood group-specific plasma may be administered
b. group O may be administered to recipients of all blood groups
c. group AB may be administered to AB recipients only
d. group A may be administered to both A and O recipients - ANSWER: d
7th Edition By Denise M Harmening 9780803668881 Chapter
1-29 Complete Guide .
How would the hematocrit of a patient with chronic anemia be affected by the transfusion of a unit of
Whole Blood containing 475 mL of blood, vs 2 units of Red Blood Cells each with a total volume of 250
mL?
a. patient's hematocrit would be equally affected by the Whole Blood or the Red Blood cells
b. Red blood cells would provide twice the increment in hematocrit as the whole blood
c. whole blood would provide twice the increment in hematocrit as the red blood cells
d. whole blood would provide a change in hematocrit slightly less than the red blood cells - ANSWER:
b
Each unit of whole blood or rbcs will increase the hematocrit 3%-5%, so 2 units of rbcs will increase
the hematocrit by twice as must as 1 unit of whole blood
After checking the inventory, it was noted that there were no units on the shelf marked "May issue as
Uncrossmatched: For Emergency Only". Which of the following should be placed on this shelf?
a. 1 unit of each of the ABO blood groups
b. units of group O, Rh-positive whole blood
c. units of group O, Rh-negative red blood cells
d. any units that are expiring at midnight - ANSWER: c
For emergency transfusions, group O-rbc units should be used.
The primary indication for granulocyte transfusion is:
a. prophylactic treatment for infection
b. additional supportive therapy in those patients who are responsive to antibiotic therapy
c. clinical situations where bone marrow recovery is not anticipated
d. severe neutropenia with an infection that is nonresponsive to antibiotic therapy - ANSWER: d
Granulocyte transfusions may be indicated for severely neutropenic patients with infection not
controlled by antibiotic therapy, who are expected to recover bone marrow production of white cells.
A 42 yr old male of average body mass has a history of chronic anemia requiring transfusion support.
Two units of red blood cells are transfused. If the pretransfusion hemoglobin was 7.0 g/dl (70g/L), the
expected posttransfusion hemoglobin concentration should be:
a. 8.0 g/dl (80g/L)
b. 9.0 g/dl (90g/L)
c. 10.0 g/dl (100 g/L)
d. 11.0 g/dl (110 g/L) - ANSWER: b
Each unit of rbcs is expected to increase the hemoglobin level by 1-1.5 g/dl (10-15 g/L).
How many units of red blood cells are required to raise the hematocrit of a 70 kg nonbleeding man
from 24% to 30%?
a. 1
b. 2
c. 3
d. 4 - ANSWER: b
, Each unit of rbcs is expected to increase the hematocrit level 3%-5%, so it would take 2 units to raise
the level 6%.
For which of the following transfusion candidates would CMV-seronegative blood be most likely
indicated?
a. renal dialysis patients
b. sickle cell patient
c. bone marrow and hematopoietic cell transplant recipients
d. CMV-seropositive patients - ANSWER: c
CMV-seronegative or leukoreduced blood products should be administered to immunocompromised
patients, including bone marrow and hematopoietic cell transplant recipients.
Although ABO compatibility is preferred, ABO incompatible product may be administered when
transfusing:
a. Single-Donor Plasma
b. Cryoprecipitated AHF
c. FFP
d. Granulocytes - ANSWER: b
Cryoprecipitate contains ABO antibodies so one should consider giving ABO compatible, especially
when infusing large volumes.
Transfusion of plateletpheresis products from HLA-compatible donors is the preferred treatment:
a. recently diagnosed cases of TTP with severe thrombocytopenia
b. acute leukemia in relapse with neutropenia, thrombocytopenia and sepsis
c. immune thrombocytopenic purpura
d. severely thrombocytopenic patients, known to be refractory to random donor platelets - ANSWER:
d
Class I HLA antigens on platelets are a known cause for platelet refractoriness. Leukoreduction of
blood products is used as a mechanism to reduce or prevent patients from developing antibodies.
Washed red blood cells are indicated in which of the following situations?
a. an IgA-deficient patient with a history of transfusion-associated anaphylaxis
b. a pregnant woman with a history of hemolytic disease of the newborn
c. a patient with a positive DAT and red cell autoantibody
d. a newborn with a hematocrit of <30% - ANSWER: a
Patients with IgA deficiency who have had anaphylactic transfusion reactions should receive washed
rbcs. Anaphylactic reactions are typically caused by anti-IgA in the recipient. Washing removes plasma
IgA from the donor unit cells
Which of the following is consistent with standard blood bank procedure governing the infusion of
FFP?
a. only blood group-specific plasma may be administered
b. group O may be administered to recipients of all blood groups
c. group AB may be administered to AB recipients only
d. group A may be administered to both A and O recipients - ANSWER: d
