Practice 3rd Edition By Lilley ALL Chapters .
A patient is experiencing a severe anaphylactic reaction, what medication would be given? - ANSWER:
Epinephrine
Adrenergics are drugs with effects that are similar to or mimic the effects of the - ANSWER:
sympathetic nervous system
What receptors are being stimulated that cause bronchi to dilate? - ANSWER: Beta2-adrenergic
receptors
Adrenergic agonist is used to increase - ANSWER: Vasoconstriction
Heart contractility
Blood pressure
Which adrenergic drug is for the prevention of bronchospasms? - ANSWER: Salmeterol
atenolol - ANSWER: Cardioselective Beta-Blocker
What is atenolol used for? - ANSWER: -Prevent future myocardial infractions in patients who have
previously had one
-Treatment of:
Hypertension
Angina
Management of thyrotoxicosis; blocks the symptoms of excessive thyroid activity
atenolol is thought to contribute to the development of which condition and why? - ANSWER:
Hyperglycemia, by impairing the release of insulin from the pancreatic beta-cell
What are the effects of carvedilol? - ANSWER: Acting as a:
-nonselective beta-blocker
-An Alpha1-blocker
-A calcium channel blocker (at high doses)
-possibly an antioxidant
What is the strength of carvedilol stimulation on beta receptors compared to alpha1 receptors? -
ANSWER: its action on beta receptors is 10 times stronger than that on alpha1 receptors
carvedilol is used for the treatment of - ANSWER: Heart failure
Hypertension
Angina
Cardioselective beta-blockers such as carvedilol, have a more favourable effect on - ANSWER: glucose
and cholesterol control
esmolol - ANSWER: Strong, short-acting beta1 blocker.
Esmolol is used for? - ANSWER: to provide rapid temporary control of the ventricular rate with
supraventricular tachydysrhythmias
How is esmolol administered? - ANSWER: IV, is titrated to achieve the serum levels that control the
patient's symptoms
, Solifenacin Contraindications - ANSWER: Hypersensitivity to solifenacin, gastric retention,
uncontrolled glaucoma, urinary retention
Tolterodine (Detrol) is used to treat - ANSWER: overactive bladder
What is the advantage of using Detrol? - ANSWER: Tolterodine
-They have a much lower incident of dry mouth, in part because of their pharmacological specificity
for the bladder rather than salivary glands
What are the 2 types of cholinergic receptors? - ANSWER: nicotinic and muscarinic
nicotinic receptors respond to stimulation by - ANSWER: nicotine
Where are nicotinic receptors located? - ANSWER: Located on the pre-ganglionic fiber of the
parasympathetic and sympathetic nervous systems
At recommended dosages, cholinergic drugs primarily affect the - ANSWER: muscarinic receptors
At high dosages, cholinergic drugs affect the - ANSWER: nicotinic receptors
The desired effect of cholinergic drugs comes from the stimulation of - ANSWER: muscarinic receptors
many of the undesirable adverse effects of cholinergic drugs are due to the stimulation of - ANSWER:
nicotinic receptors
Cholinergic drug effects: Muscarinic Pulmonary - ANSWER: Bronchi - Increased secretion, constriction
Cholinergic drug effects: Muscarinic Cardiovascular - ANSWER: Blood vessels - Dilation
Heart rate - Slowed
Blood Pressure - Decreased
Cholinergic drug effects: Muscarinic Ocular - ANSWER: Eye - Miosis (pupil constriction), decreased
accommodation
Cholinergic drug effects: Muscarinic GI - ANSWER: GI tone - Increased
GI motility - Increased
GI sphincter - Relaxed
Cholinergic drug effects: Muscarinic GU - ANSWER: GU tone - Increased
GU motility - Increased
GU sphincter - Relaxed
Cholinergic drug effects: Muscarinic Glandular Secretions - ANSWER: Increased intestinal, lacrimal,
salivary, and sweat gland secretion
Cholinergic drug effects: Muscarinic Skeletal Muscle - ANSWER: No response
Cholinergic drug effects: Nicotinic Pulmonary - ANSWER: Bronchi - none
Cholinergic drug effects: Nicotinic Cardiovascular - ANSWER: Blood vessels - Constriction
Heart rate - Increased
Blood pressure - Increased
Cholinergic drug effects: Nicotinic Ocular - ANSWER: Eye - Miosis (pupil constriction), decreased
accommodation
Cholinergic drug effects: Nicotinic GI - ANSWER: GI tone - Increased