Nurs 5315 Adv Patho Exam 2 Set 1 COMPLETE QUESTIONS AND ANSWERS.

Nurs 5315: Adv Patho Exam 2 Set 1
COMPLETE QUESTIONS AND ANSWERS



First //,5 //,steps //,in //,the //,inflammatory //,process //,- //,(correct //,answer) //,-
1. //,mast //,cell //,degranulation

2. //,activation //,of //,coagulation //,cascade

3. //,activation //,of //,kinin //,cascade

4. //,release //,of //,chemotactic //,factors

5.Activation //,of //,the //,complement //,cascade

Role/function //,in //,the //,inflammatory //,process: //,Complement //,- //,(correct //,answer) //,-
Form //,the //,membrane //,attack //,complex //,

bacterial //,lysis

vasodilation

Increased //,vascular //,permeability

triggers //,mast //,cell //,degranulation

chemotaxis

opsonization //,- //,opsonins //,tag //,foreign //,pathogens //,for //,elimination //,by //,phagocytes

Role/function //,in //,the //,inflammatory //,process: //,kinin //,- //,(correct //,answer) //,-
turned //,into //,bradykinin //,which //,is //,responsible //,for //,pain, //,chemotaxis //,and //,Increased //,vascul
ar //,permeability //,and //,vasodilation

Role/function //,in //,the //,inflammatory //,process: //,Coagulation //,cascade //,- //,(correct //,answer) //,-
plays //,role //,in //,activating //,the //,kinin //,system

Factor //,XII //,
(Hagemon //,factor) //,activates //,kinin //,and //,forms //,a //,fibrin //,mesh //,to //,stop //,bleeding //,and //,trap
//,microorganisms

,Role/function //,in //,the //,inflammatory //,process: //,chemotactic //,factors //,- //,(correct //,answer) //,-once
//,released //,attract //,neutrophils, //,eosinophils //,and //,monocytes //,for //,phagocytosis


Role/function //,in //,the //,inflammatory //,process: //,Neutrophils //,- //,(correct //,answer) //,-show //,up //,at
//,the //,site //,of //,injury //,in //,6-8 //,hours


Neutrophils //,express //,and //,release //,cytokines, //,which //,in //,turn //,amplify //,inflammatory //,reaction
s //,by //,several //,other //,cell //,types. //,In //,addition //,to //,recruiting //,and //,activating //,other //,cells //,of
//,the //,immune //,system, //,neutrophils //,play //,a //,key //,role //,in //,the //,front-
line //,defense //,against //,invading //,pathogens.

Role/function //,in //,the //,inflammatory //,process: //,monocytes //,- //,(correct //,answer) //,-
Show //,up //,in //,1-7 //,days

become //,macrophages

present //,antigens //,to //,the //,CD4 //,cell //,which //,leads //,to //,Tcell //,immunity //,which //,leads //,to //,B //
,cell //,immunity


Releases //,IL1, //,IL6, //,TNF //,and //,growth //,factors

Role/function //,in //,the //,inflammatory //,process: //,Mast //,cell //,degranulation //,- //,
(correct //,answer) //,-triggers //,the //,activation //,of //,the //,acute //,phase //,reactants

This //,leads //,to //,the //,release //,of //,histamine, //,cytokines, //,leukotrienes, //,platelet //,activation //,fact
or //,and //,prostaglandins

Role/function //,in //,the //,inflammatory //,process: //,Histamine //,1 //,(H1) //,- //,(correct //,answer) //,-
promotes //,inflammation

smooth //,muscles, //,i.e. //,bronchi //,- //,asthma //,causes //,bronchoconstriction

Role/function //,in //,the //,inflammatory //,process: //,Histamine //,2 //,(H2) //,- //,(correct //,answer) //,-anti-
inflammatory //,properties

gastric //,mucosa

Role/function //,in //,the //,inflammatory //,process: //,cytokines //,- //,(correct //,answer) //,-
IL4 //,early //,in //,the //,inflammation

IL //,13 //,later //,in //,inflammation

TNF

Role/function //,in //,the //,inflammatory //,process: //,leukotrienes //,- //,(correct //,answer) //,-
released //,when //,mast //,cell //,degranulates //,cause //,vasodilation

attract //,neutrophils, //,monocytes //,eosinophils

, Singular //,impacts //,leukotrienes

Role/function //,in //,the //,inflammatory //,process: //,prostaglandins //,- //,(correct //,answer) //,-
released //,when //,the //,mast //,cell //,degranulates

produced //,by //,the //,arachidonic //,pathway

cause //,vasodilation, //,platelet //,aggregation, //,pain //,and //,fever

Role/function //,in //,the //,inflammatory //,process: //,platelet-activating //,factor //,- //,(correct //,answer) //,-
derived //,from //,fatty //,acids //,in //,the //,plasma //,membrane

produced //,by //,neutrophils, //,monocytes, //,endothelial //,and //,platelets

cause //,endothelial //,cell //,retraction, //,increases //,vascular //,permeability, //,activates //,platelets, //,enh
ances //,leukocyte //,adhesion //,to //,endothelial //,cell

Steps //,in //,the //,arachidonic //,acid //,pathway //,- //,(correct //,answer) //,-
Linoleic //,acid //,plus //,phospholipase //,A2 //,make //,arachidonic //,acid //,(AA)

AA //,plus //,COX1 //,or //,COX //,2 //,make //,Prostaglandins

Prostaglandins //,from //,COX1 //,maintain //,homeostasis

gastric //,mucosa

platelet //,aggregation

fluid/electrolyte //,imbalance

Prostaglandins //,from //,COX2 //,assist //,in //,the //,inflammatory //,process //,via //,pain, //,fever

help //,with //,homeostasis //,via //,renal //,function

tissue //,repair

reproduction //,development

Function //,of //,arachidonic //,acid //,pathway //,- //,(correct //,answer) //,-
The //,arachidonic //,pathway //,is //,the //,biochemical //,process //,responsible //,for //,the //,synthesis //,of //,
prostaglandins //,(See //,concept //,map).

It //,is //,made //,from //,linoleic //,acid //,which //,is //,part //,of //,the //,phospholipid //,cell //,membrane.

COX2 //,note //,of //,caution //,- //,(correct //,answer) //,-
While //,COX2 //,inhibitors //,block //,the //,inflammatory //,function //,of //,prostaglandins, //,they //,can //,als
o //,impair //,renal //,function.

NSAIDS //,- //,(correct //,answer) //,-inhibit //,both //,COX1 //,and //,COX2 //,prostaglandin //,synthesis