BBL FINAL LESSON 12-22 QUESTIONS
AND VERIFIED ANSWERS|100%
CORRECT|GRADE A+
Of the 22 amino acids, which of the following pair is NOT used in catabolic reactions as bioenergetic
fuel?
A. Selenocysteine and pyrrolysine
B. Leucine and valine
C. Serine and threonine
D. Methionine and tryptophan - ANSWER A. Selenocysteine and pyrrolysine
Which of these is a necessary precursor enzyme for the incorporation of nitrogen into urea?
A. glutamate dehydrogenase
B. phenylalanine hydroxylase
C. oxidative decarboxylase
D. peptidyl transferase - ANSWER A. glutamate dehydrogenase
In a reaction of the Urea Cycle, aspartate condenses with citrulline to form argininosuccinate. Which of
the following is incorrect?
A. Fumarate is also produced in this reaction
B. One of the products of this reaction is arginine
C. This reaction takes place in the mitochondrial matrix
D. This condensation reaction requires ATP - ANSWER C. This reaction takes place in the mitochondrial
matrix
Which two amino acids are deaminated by oxidative deamination only?
A. Serine and threonine
B. Glutamate and glutamine
C. Aspartate and asparagine
D. Tyrosine and serine - ANSWER B. Glutamate and glutamine
,Glucogenic amino acids are utilized as substrate for
A. Anaerobic respiration
B. Fatty acid synthesis
C. Gluconeogenesis
D. None of the above - ANSWER C. Gluconeogenesis
Alanine functions as a transport form of pyruvate between skeletal muscles, where it is formed from
pyruvate, to the liver where it is converted back to pyruvate.
A. True
B. False - ANSWER A. True
The synthesis of glutamine from glutamate requires
A. ATP
B. Pyridoxal phosphate
C. ATP & NH3+
D. NADH & ATP - ANSWER C. ATP & NH3+
In the transaminase reaction between glutamate/pyruvate, the amino acid produced is
A. Aspartate
B. Alanine
C. Alpha ketoglutarate
D. Serine - ANSWER B. Alanine
The metabolism of serine to pyruvate is an example of
A. Oxidative deamination
B. Transamination
C. Anaerobic metabolism
D. Substitution reaction - ANSWER A. Oxidative deamination
,Glucogenic amino acids are utilized in the gluconeogenic pathway of the liver.
A. True
B. False - ANSWER A. True
Glutamate is aminated to glutamine by the enzyme
A. Glutamate dehydrogenase
B. Glutaminase
C. Glutamine synthetase
D. Glutamine oxidase - ANSWER C. Glutamine synthetase
N-acetyl-glutamate regulates the following pathway
A. TCA Cycle
B. ETS/ OX-Phos
C. Glycolysis
D. Urea Cycle - ANSWER D. Urea Cycle
How is glutamate dehydrogenase allosterically controlled?
A. Activated by ADP and GDP
B. Inhibited by ADP and GTP
C. Activated by ATP and GTP
D. Activated by UTP and CTP - ANSWER C. Activated by ATP and GTP
Which two amino acids are NOT substrate for aminotransferases?
A. Alanine and aspartate
B. Serine and threonine
C. Oxaloacetate and malate
D. Leucine and isoleucine - ANSWER B. Serine and threonine
, The cofactor found in the active site of ALL transaminase enzymes is
A. Cobalamin phosphate
B. Pyridoxal phosphate
C. Ferrodoxin
D. Biotin - ANSWER B. Pyridoxal phosphate
Alanine is transported from the skeletal muscle to liver to be back converted to pyruvate. The pyruvate
in the liver is then used for
A. Glycolysis
B. Homolactic Fermentation
C. Gluconeogensis
D. Fatty Acid synthesis - ANSWER C. Gluconeogensis
Glutamate is back converted to alpha ketoglutarate in liver mitochondria by
A. Glutaminase
B. Glutamate synthase
C. Glutamate dehydrogenase
D. All of the above - ANSWER C. Glutamate dehydrogenase
In the mechanism of all transaminases, the pyridoxal phosphate
A. becomes reduced and the amino acid is oxidized
B. receives the amine group through a Schiff's base reaction
C. becomes carboxylated
D. All of the above - ANSWER B. receives the amine group through a Schiff's base reaction
The biological location of the Urea Cycle is
A. Kidney tubule cells
B. Pancreatic exocrine cells
C. Skeletal muscle cells
AND VERIFIED ANSWERS|100%
CORRECT|GRADE A+
Of the 22 amino acids, which of the following pair is NOT used in catabolic reactions as bioenergetic
fuel?
A. Selenocysteine and pyrrolysine
B. Leucine and valine
C. Serine and threonine
D. Methionine and tryptophan - ANSWER A. Selenocysteine and pyrrolysine
Which of these is a necessary precursor enzyme for the incorporation of nitrogen into urea?
A. glutamate dehydrogenase
B. phenylalanine hydroxylase
C. oxidative decarboxylase
D. peptidyl transferase - ANSWER A. glutamate dehydrogenase
In a reaction of the Urea Cycle, aspartate condenses with citrulline to form argininosuccinate. Which of
the following is incorrect?
A. Fumarate is also produced in this reaction
B. One of the products of this reaction is arginine
C. This reaction takes place in the mitochondrial matrix
D. This condensation reaction requires ATP - ANSWER C. This reaction takes place in the mitochondrial
matrix
Which two amino acids are deaminated by oxidative deamination only?
A. Serine and threonine
B. Glutamate and glutamine
C. Aspartate and asparagine
D. Tyrosine and serine - ANSWER B. Glutamate and glutamine
,Glucogenic amino acids are utilized as substrate for
A. Anaerobic respiration
B. Fatty acid synthesis
C. Gluconeogenesis
D. None of the above - ANSWER C. Gluconeogenesis
Alanine functions as a transport form of pyruvate between skeletal muscles, where it is formed from
pyruvate, to the liver where it is converted back to pyruvate.
A. True
B. False - ANSWER A. True
The synthesis of glutamine from glutamate requires
A. ATP
B. Pyridoxal phosphate
C. ATP & NH3+
D. NADH & ATP - ANSWER C. ATP & NH3+
In the transaminase reaction between glutamate/pyruvate, the amino acid produced is
A. Aspartate
B. Alanine
C. Alpha ketoglutarate
D. Serine - ANSWER B. Alanine
The metabolism of serine to pyruvate is an example of
A. Oxidative deamination
B. Transamination
C. Anaerobic metabolism
D. Substitution reaction - ANSWER A. Oxidative deamination
,Glucogenic amino acids are utilized in the gluconeogenic pathway of the liver.
A. True
B. False - ANSWER A. True
Glutamate is aminated to glutamine by the enzyme
A. Glutamate dehydrogenase
B. Glutaminase
C. Glutamine synthetase
D. Glutamine oxidase - ANSWER C. Glutamine synthetase
N-acetyl-glutamate regulates the following pathway
A. TCA Cycle
B. ETS/ OX-Phos
C. Glycolysis
D. Urea Cycle - ANSWER D. Urea Cycle
How is glutamate dehydrogenase allosterically controlled?
A. Activated by ADP and GDP
B. Inhibited by ADP and GTP
C. Activated by ATP and GTP
D. Activated by UTP and CTP - ANSWER C. Activated by ATP and GTP
Which two amino acids are NOT substrate for aminotransferases?
A. Alanine and aspartate
B. Serine and threonine
C. Oxaloacetate and malate
D. Leucine and isoleucine - ANSWER B. Serine and threonine
, The cofactor found in the active site of ALL transaminase enzymes is
A. Cobalamin phosphate
B. Pyridoxal phosphate
C. Ferrodoxin
D. Biotin - ANSWER B. Pyridoxal phosphate
Alanine is transported from the skeletal muscle to liver to be back converted to pyruvate. The pyruvate
in the liver is then used for
A. Glycolysis
B. Homolactic Fermentation
C. Gluconeogensis
D. Fatty Acid synthesis - ANSWER C. Gluconeogensis
Glutamate is back converted to alpha ketoglutarate in liver mitochondria by
A. Glutaminase
B. Glutamate synthase
C. Glutamate dehydrogenase
D. All of the above - ANSWER C. Glutamate dehydrogenase
In the mechanism of all transaminases, the pyridoxal phosphate
A. becomes reduced and the amino acid is oxidized
B. receives the amine group through a Schiff's base reaction
C. becomes carboxylated
D. All of the above - ANSWER B. receives the amine group through a Schiff's base reaction
The biological location of the Urea Cycle is
A. Kidney tubule cells
B. Pancreatic exocrine cells
C. Skeletal muscle cells
